Detailed information of TA system TA089442

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /BrnT(toxin)
• Location: 567708..568209
• Replicon: chromosome
• Accession: NZ_CP025000
• Organism: Idiomarina sp. X4

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: CWC33_RS02785
• Protein ID: WP_100690689.1
• Coordinates: 567943..568209 (-)
• Length: 89 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: CWC33_RS02780
• Protein ID: WP_100690688.1
• Coordinates: 567708..567956 (-)
• Length: 83 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CWC33_RS02760	563341..563865	-	525	WP_100690684.1	hypothetical protein	-
CWC33_RS02765	564033..565610	-	1578	WP_100690685.1	glutamine-hydrolyzing GMP synthase	-
CWC33_RS02770	565622..567091	-	1470	WP_100690686.1	IMP dehydrogenase	-
CWC33_RS02775	567322..567687	-	366	WP_100690687.1	hypothetical protein	-
CWC33_RS02780	567708..567956	-	249	WP_100690688.1	CopG family transcriptional regulator	Antitoxin
CWC33_RS02785	567943..568209	-	267	WP_100690689.1	BrnT family toxin	Toxin
CWC33_RS02790	568358..569575	-	1218	WP_100690690.1	hypothetical protein	-
CWC33_RS02795	569765..571519	+	1755	WP_100690691.1	hypothetical protein	-
CWC33_RS02800	571659..572840	-	1182	WP_100690692.1	BCCT family transporter	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (6-81)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 89 a.a.
• Molecular weight: 10475.06 Da
• Isoelectric Point: 10.0690

>T89442 WP_100690689.1 NZ_CP025000:c568209-567943 [Idiomarina sp. X4]
MLKFEFDSGKSLSNLQKHGIDFYSAQHLWNDSELLEIPAKTKDEKRYLIIAKYKGKHWSAVVTYRREVIRIISVRRSRIS
EVKLYESE

Nucleotide

• Length: 267 bp

>T89442 NZ_CP025000:c568209-567943 [Idiomarina sp. X4]
ATGTTGAAGTTTGAATTTGATAGCGGCAAGAGTTTATCAAACCTCCAAAAGCATGGGATTGATTTTTATTCAGCTCAACA
TCTATGGAATGACTCTGAGCTGCTTGAAATTCCAGCTAAAACAAAAGATGAGAAGCGTTATTTAATAATAGCCAAGTACA
AGGGAAAGCACTGGTCAGCAGTAGTCACTTATCGGCGTGAGGTTATTAGAATAATATCTGTGCGGCGCTCAAGGATTAGT
GAGGTGAAGCTTTATGAAAGCGAGTGA

Antitoxin

Protein

• Length: 83 a.a.
• Molecular weight: 9778.11 Da
• Isoelectric Point: 4.6475

>AT89442 WP_100690688.1 NZ_CP025000:c567956-567708 [Idiomarina sp. X4]
MKASEFDEKFDSDEDVIDELEFEKAKRPMRKQKRVNVDFPEWMLESLDEEAARIGVTRQSIIKVWLAERLEQIEKHNIGK
QV

Nucleotide

• Length: 249 bp

>AT89442 NZ_CP025000:c567956-567708 [Idiomarina sp. X4]
ATGAAAGCGAGTGAATTTGACGAAAAGTTTGACTCTGACGAAGACGTTATAGATGAACTTGAGTTTGAAAAGGCTAAAAG
ACCTATGCGTAAACAAAAGCGCGTGAATGTTGATTTTCCTGAATGGATGCTTGAGTCTTTGGATGAGGAAGCAGCGCGTA
TTGGGGTGACTCGCCAGTCAATTATTAAAGTTTGGCTGGCAGAGCGATTAGAGCAAATCGAAAAGCATAATATTGGGAAA
CAAGTGTAA