Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) phd-doc/HTH_IclR(antitoxin)
Location 1592631..1594363 Replicon chromosome
Accession NZ_CP024996
Organism Herbaspirillum rubrisubalbicans strain DSM 11543

Toxin (Protein)


Gene name doc Uniprot ID -
Locus tag RC54_RS07045 Protein ID WP_061789042.1
Coordinates 1592631..1593509 (+) Length 293 a.a.

Antitoxin (Protein)


Gene name phd Uniprot ID -
Locus tag RC54_RS07050 Protein ID WP_026052222.1
Coordinates 1593530..1594363 (+) Length 278 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
RC54_RS07020 1588501..1589286 + 786 WP_017454058.1 ABC transporter ATP-binding protein -
RC54_RS07025 1589354..1590349 + 996 WP_058894740.1 ABC transporter substrate-binding protein -
RC54_RS07030 1590352..1591215 + 864 WP_058894741.1 ABC transporter permease -
RC54_RS07035 1591257..1592027 + 771 WP_058894742.1 SDR family oxidoreductase -
RC54_RS07040 1592085..1592621 + 537 WP_058894743.1 cupin domain-containing protein -
RC54_RS07045 1592631..1593509 + 879 WP_061789042.1 alpha/beta hydrolase Toxin
RC54_RS07050 1593530..1594363 + 834 WP_026052222.1 IclR family transcriptional regulator Antitoxin
RC54_RS07055 1594365..1595189 + 825 WP_058894745.1 SDR family oxidoreductase -
RC54_RS07060 1595182..1596873 + 1692 WP_058894746.1 thiamine pyrophosphate-binding protein -
RC54_RS07065 1596885..1597685 + 801 WP_017454067.1 aspartate dehydrogenase -
RC54_RS07070 1597711..1599186 + 1476 WP_174526081.1 aldehyde dehydrogenase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Alpha/beta hydrolase fold-1

(50-282)

Antitoxin

Transcription regulator IclR, N-terminal

(20-68)


Sequences

Toxin        


Download         Length: 293 a.a.        Molecular weight: 31222.72 Da        Isoelectric Point: 7.1995

>T89420 WP_061789042.1 NZ_CP024996:1592631-1593509 [Herbaspirillum rubrisubalbicans]
MPAMNPIVSVNDEQLLHAPLALLEGRFAQRSVALPGGQISYRSCGSGPVVVLLHGISSGAASWLRCALELASCARVIAWN
APGYGHSTPLPMSVPKASDYALRLQQMLQALEIEQCVLVGHSLGALMAAAYLACGDGRARSTLLADPALGYGAPGKQQRA
QQVRDERLGALHRLGIPGLAQQPTRLLSDHADAEQHAWVRWNMQWLDAAGYTQAVQLLCGDDIELYLNAAPRRGLSVACG
AEDIVTTPQASEALARQFGLFFHKVHAAGHASYIEQPSQFAALVRAQLTSTY

Download         Length: 879 bp

>T89420 NZ_CP024996:1592631-1593509 [Herbaspirillum rubrisubalbicans]
ATGCCTGCCATGAACCCCATCGTTTCGGTCAACGACGAGCAACTCCTGCACGCGCCGCTGGCGCTGCTCGAAGGCCGCTT
TGCCCAGCGTAGCGTTGCCCTGCCGGGCGGCCAGATCAGCTATCGCAGTTGCGGCAGCGGGCCGGTGGTGGTGCTCTTGC
ATGGCATCAGTTCGGGCGCCGCCTCTTGGCTGCGCTGCGCCTTGGAGCTGGCCTCCTGCGCCCGGGTGATCGCCTGGAAT
GCGCCGGGCTATGGACATTCCACGCCACTGCCCATGAGCGTGCCCAAGGCCAGCGACTATGCACTGCGCTTGCAGCAGAT
GCTGCAAGCCTTGGAGATCGAGCAATGCGTGCTGGTCGGTCATTCGCTGGGGGCCTTGATGGCCGCCGCTTATCTGGCCT
GCGGCGATGGGCGTGCGCGCAGCACCCTGCTGGCCGATCCGGCCCTGGGTTACGGTGCACCCGGCAAGCAACAGCGGGCG
CAGCAGGTACGCGATGAGCGCCTGGGGGCACTGCACCGGCTGGGTATCCCTGGCCTGGCGCAGCAACCTACGCGCCTGCT
GTCGGACCATGCCGACGCCGAGCAGCACGCCTGGGTGCGCTGGAACATGCAATGGCTGGATGCGGCCGGTTACACCCAGG
CCGTGCAATTGTTGTGCGGCGACGATATCGAGCTCTATCTGAACGCAGCGCCACGGCGGGGACTGTCGGTGGCCTGCGGC
GCGGAAGATATCGTCACCACCCCCCAGGCCAGTGAAGCGCTGGCCCGGCAATTTGGACTTTTCTTTCATAAGGTGCACGC
CGCCGGCCATGCCAGCTATATCGAGCAGCCGTCGCAATTTGCCGCGCTGGTGCGCGCGCAACTCACCTCAACCTACTAA

Antitoxin


Download         Length: 278 a.a.        Molecular weight: 30797.35 Da        Isoelectric Point: 6.5033

>AT89420 WP_026052222.1 NZ_CP024996:1593530-1594363 [Herbaspirillum rubrisubalbicans]
MSKPVMPEEESQDKYSVPGLERGLRLLCEFSRQDKTLSAPELARRLDIPRSTVFRLLATLERMGFVERADGGRDYRLGMS
VLRLGFEYLASLELTEIGRPLLDRLRDEIGYSCNLVVRDGRSIVYVAKSVTQTAFTSHVNVGTRLPAHATVLGRVLLEDL
SLPQLRALYPEQHLEVFSSNTPKTVVELFDMVQADKERGFVLQEGFFETSISTVAAPVRDHSGLVVAALGATIPSPHIDA
SQLDVIVARVRETAAELSRLLDHAPERGAKVVNMWRG

Download         Length: 834 bp

>AT89420 NZ_CP024996:1593530-1594363 [Herbaspirillum rubrisubalbicans]
ATGAGCAAACCTGTGATGCCAGAAGAAGAATCGCAAGACAAGTATTCCGTCCCCGGCCTGGAACGTGGCCTGCGCCTGCT
GTGCGAATTCAGCCGTCAGGACAAGACGCTGTCGGCCCCTGAACTGGCGCGTCGCCTGGATATCCCGCGCTCCACCGTGT
TTCGCCTGCTGGCCACGCTGGAACGCATGGGCTTCGTCGAGCGTGCCGATGGCGGACGTGACTACCGCCTGGGCATGTCG
GTGTTGCGCCTGGGCTTCGAATACCTGGCTTCGCTGGAATTGACCGAGATCGGCCGTCCGCTGCTGGACCGCCTGCGCGA
TGAGATCGGCTATTCCTGCAATCTGGTGGTACGCGATGGCCGCTCCATCGTCTATGTCGCCAAGTCGGTCACCCAGACCG
CCTTCACCAGCCACGTCAACGTCGGCACCCGCCTGCCGGCGCACGCCACCGTGCTGGGCCGCGTGCTGCTGGAAGACCTG
AGCCTGCCGCAACTGCGCGCGCTGTATCCCGAACAGCACCTGGAAGTCTTCTCCAGCAATACCCCCAAGACCGTGGTCGA
ACTGTTCGACATGGTGCAGGCCGACAAGGAGCGCGGCTTCGTGTTGCAGGAAGGTTTCTTCGAAACCAGCATCTCCACCG
TGGCCGCGCCGGTGCGCGATCACTCCGGCCTGGTGGTGGCTGCGCTGGGGGCGACGATCCCTTCGCCGCACATCGATGCC
AGCCAGCTCGACGTGATCGTGGCGCGTGTGCGCGAGACCGCGGCCGAACTGTCCCGCCTGCTGGACCACGCCCCCGAACG
TGGCGCCAAGGTGGTCAACATGTGGCGGGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References