Detailed information of TA system TA089348

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): /RES-TIGR02293
• Location: 1987284..1988194
• Replicon: chromosome
• Accession: NZ_CP024956
• Organism: Pectobacterium atrosepticum strain 36A

Toxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: CVS35_RS08885
• Protein ID: WP_039291191.1
• Coordinates: 1987724..1988194 (+)
• Length: 157 a.a.

Antitoxin (Protein)

• Gene name: -
• Uniprot ID: -
• Locus tag: CVS35_RS08880
• Protein ID: WP_039291190.1
• Coordinates: 1987284..1987727 (+)
• Length: 148 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CVS35_RS08855	1982461..1983450	+	990	WP_039291185.1	iron ABC transporter permease	-
CVS35_RS08860	1983443..1984474	+	1032	WP_039291186.1	iron ABC transporter permease	-
CVS35_RS08865	1984502..1985341	+	840	WP_199559463.1	ABC transporter ATP-binding protein	-
CVS35_RS08870	1985619..1987070	+	1452	WP_039291188.1	ATP-dependent RNA helicase RhlE	-
CVS35_RS08875	1987111..1987224	-	114	Protein_1685	EamA family transporter	-
CVS35_RS08880	1987284..1987727	+	444	WP_039291190.1	DUF2384 domain-containing protein	Antitoxin
CVS35_RS08885	1987724..1988194	+	471	WP_039291191.1	RES family NAD+ phosphorylase	Toxin
CVS35_RS08890	1988251..1989480	-	1230	WP_039291193.1	peptidase T	-
CVS35_RS08895	1989621..1991216	+	1596	WP_039291195.1	ABC transporter substrate-binding protein	-
CVS35_RS08900	1991263..1991934	-	672	WP_039291197.1	epoxyqueuosine reductase QueH	-
CVS35_RS08905	1992178..1993110	+	933	WP_039291199.1	tRNA dihydrouridine(16) synthase DusC	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• RES domain (3-145)

Antitoxin

• Antitoxin Xre (16-147)

Sequences

Toxin

Protein

• Length: 157 a.a.
• Molecular weight: 17637.08 Da
• Isoelectric Point: 4.4093

>T89348 WP_039291191.1 NZ_CP024956:1987724-1988194 [Pectobacterium atrosepticum]
MILYRLTKTKYLSTAWTGYGAKEAGGRWNSIGTSMVYVSETASLAMLETLVHLHAAQILDYYTLMRIDVPEDQIQSADMD
ELPDNWAAEEAPPDLAVYGDAWIFTKGSIALRVPSALSPVEYNYLLNPEHPDFYGIIQMAEIIPFQFDSRLKPDRK

Nucleotide

• Length: 471 bp

>T89348 NZ_CP024956:1987724-1988194 [Pectobacterium atrosepticum]
TTGATTCTCTATCGGCTTACAAAGACAAAGTATCTTTCTACAGCCTGGACGGGATACGGAGCAAAAGAGGCTGGAGGCCG
CTGGAATAGTATTGGCACCTCGATGGTTTATGTATCAGAAACCGCATCGCTTGCCATGCTGGAGACGCTGGTACATCTGC
ATGCAGCGCAGATCCTGGATTATTACACGCTAATGCGTATCGATGTGCCTGAGGATCAGATTCAGAGTGCCGATATGGAC
GAATTGCCAGACAACTGGGCTGCTGAAGAAGCGCCGCCAGATCTGGCTGTATACGGTGATGCATGGATCTTTACCAAAGG
TTCGATAGCGTTGCGAGTCCCCAGCGCCCTATCGCCTGTAGAGTATAACTACCTGTTAAACCCTGAACACCCAGATTTCT
ACGGGATCATTCAGATGGCAGAGATTATACCGTTCCAGTTTGATAGCCGGCTAAAGCCCGATCGTAAATAA

Antitoxin

Protein

• Length: 148 a.a.
• Molecular weight: 16345.69 Da
• Isoelectric Point: 9.5903

>AT89348 WP_039291190.1 NZ_CP024956:1987284-1987727 [Pectobacterium atrosepticum]
MKTFSLSTTQTRPPRLWQVAGLNNSDGVALLGQINEGLEGKVANLIADWAKITQNDLRKMSGIPSTTFSRSVKARFSADQ
SERLVRIIRVIDRAVELFEGDKDEAQKWLNEPNRALGGKVPAELMVSETGAYEVMKLLTRLEHGVYS

Nucleotide

• Length: 444 bp

>AT89348 NZ_CP024956:1987284-1987727 [Pectobacterium atrosepticum]
ATGAAAACATTTAGCTTATCCACGACTCAGACCAGGCCGCCCCGTTTATGGCAGGTGGCCGGATTAAACAATTCTGATGG
TGTGGCGCTTCTGGGACAGATTAACGAAGGCCTTGAGGGCAAGGTTGCTAACCTTATCGCTGACTGGGCGAAGATAACGC
AAAACGACCTGCGTAAAATGTCCGGCATTCCGTCAACGACGTTTAGCCGCAGCGTCAAAGCGCGATTTAGCGCCGATCAA
AGTGAACGGCTGGTGCGTATCATCCGTGTCATTGATCGGGCGGTAGAACTGTTCGAAGGTGATAAGGACGAGGCTCAAAA
ATGGTTGAATGAGCCAAACCGAGCGCTTGGCGGGAAAGTGCCAGCAGAACTGATGGTATCCGAAACCGGGGCTTACGAAG
TCATGAAATTGCTCACGCGCCTGGAACATGGTGTGTACTCTTGA