Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 1935816..1936540 Replicon chromosome
Accession NZ_CP024956
Organism Pectobacterium atrosepticum strain 36A

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag CVS35_RS08640 Protein ID WP_039291161.1
Coordinates 1936220..1936540 (+) Length 107 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag CVS35_RS08635 Protein ID WP_039291159.1
Coordinates 1935816..1936151 (+) Length 112 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CVS35_RS08610 1931542..1932468 + 927 WP_039291148.1 hypothetical protein -
CVS35_RS08615 1932563..1933450 + 888 WP_039291149.1 50S ribosome-binding GTPase -
CVS35_RS22580 1933634..1933792 + 159 WP_155242703.1 hypothetical protein -
CVS35_RS08620 1933939..1934772 + 834 WP_039291153.1 hypothetical protein -
CVS35_RS08625 1934830..1935180 + 351 WP_039291155.1 hypothetical protein -
CVS35_RS08630 1935303..1935776 + 474 WP_039291157.1 DNA repair protein RadC -
CVS35_RS08635 1935816..1936151 + 336 WP_039291159.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
CVS35_RS08640 1936220..1936540 + 321 WP_039291161.1 TA system toxin CbtA family protein Toxin
CVS35_RS08645 1936658..1937491 + 834 WP_039294889.1 DUF4942 domain-containing protein -
CVS35_RS08650 1937623..1937820 + 198 WP_051122287.1 hypothetical protein -
CVS35_RS08655 1938379..1939407 - 1029 WP_011094382.1 subclass B3 metallo-beta-lactamase CAR-1 -
CVS35_RS08660 1939519..1940466 + 948 WP_039291164.1 LysR family transcriptional regulator -
CVS35_RS08665 1940810..1941028 - 219 WP_011094380.1 KTSC domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-105)

Antitoxin

Antitoxin CbeA

(7-106)


Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 12022.73 Da        Isoelectric Point: 4.7627

>T89347 WP_039291161.1 NZ_CP024956:1936220-1936540 [Pectobacterium atrosepticum]
MQTSPAIPPREDNPCPSPITVWQQLLTYLLEKHYGLTLNDTPFCEENVIQAHIDAGVTLVNAVNFLVEKYELVRIDRDGF
NWQEQSPFLTAVDVLRARRATGLLKA

Download         Length: 321 bp

>T89347 NZ_CP024956:1936220-1936540 [Pectobacterium atrosepticum]
ATGCAAACATCACCTGCAATCCCGCCACGGGAGGATAACCCCTGTCCGTCACCTATAACCGTCTGGCAGCAACTGCTGAC
CTACCTGCTGGAAAAGCACTACGGCCTGACGCTGAACGATACACCATTCTGTGAGGAAAACGTGATTCAAGCGCATATCG
ATGCTGGCGTCACGTTGGTCAATGCCGTGAATTTTCTGGTGGAAAAATACGAACTGGTGCGCATCGATCGCGACGGTTTT
AACTGGCAGGAGCAATCGCCGTTTCTCACTGCCGTTGATGTTCTCCGTGCCAGACGTGCTACCGGCTTGCTCAAAGCATA
A

Antitoxin


Download         Length: 112 a.a.        Molecular weight: 12468.28 Da        Isoelectric Point: 6.6874

>AT89347 WP_039291159.1 NZ_CP024956:1935816-1936151 [Pectobacterium atrosepticum]
MPSSNTPEWGLKCAVTPRFGARLVQEGHRLHYLADRASIVGTFSKTEAQNLERCFPELIKLLEQKLRMGELNPRQQNCVT
LHCNEWICEADTLGSVGYVYIVIYPSSAAAE

Download         Length: 336 bp

>AT89347 NZ_CP024956:1935816-1936151 [Pectobacterium atrosepticum]
ATGCCATCATCGAATACCCCTGAATGGGGACTAAAATGTGCTGTCACGCCGCGATTCGGAGCCAGGCTGGTTCAGGAAGG
TCACCGCCTGCACTATCTGGCAGACCGGGCCAGCATTGTCGGTACGTTTAGCAAAACAGAAGCCCAAAATCTGGAGCGTT
GCTTCCCTGAGCTAATTAAGCTGTTGGAGCAGAAGCTACGCATGGGGGAACTGAATCCCCGTCAGCAGAACTGCGTCACG
CTGCATTGCAACGAATGGATCTGTGAAGCCGATACGCTGGGCAGTGTTGGCTACGTGTATATTGTTATCTATCCCTCTTC
GGCAGCAGCAGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References