89340

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 79057..79592 Replicon chromosome
Accession NZ_CP024956
Organism Pectobacterium atrosepticum strain 36A

Toxin (Protein)


Gene name relE Uniprot ID Q6DB38
Locus tag CVS35_RS00340 Protein ID WP_011091708.1
Coordinates 79057..79344 (-) Length 96 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q6DB37
Locus tag CVS35_RS00345 Protein ID WP_010281712.1
Coordinates 79341..79592 (-) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CVS35_RS00320 75202..76011 + 810 WP_039296564.1 energy transducer TonB -
CVS35_RS00325 76022..76315 - 294 WP_005968196.1 DUF2623 domain-containing protein -
CVS35_RS00330 76631..77473 + 843 WP_011091706.1 23S rRNA (adenine(2030)-N(6))-methyltransferase RlmJ -
CVS35_RS00335 77602..78954 + 1353 WP_039296560.1 glutathione-disulfide reductase -
CVS35_RS00340 79057..79344 - 288 WP_011091708.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CVS35_RS00345 79341..79592 - 252 WP_010281712.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CVS35_RS00350 79848..80753 + 906 WP_039296557.1 siderophore-interacting protein -
CVS35_RS00355 80788..81543 - 756 WP_039296553.1 thiol:disulfide interchange protein DsbG -
CVS35_RS00360 81764..82387 + 624 WP_039296550.1 LysE family translocator -
CVS35_RS00365 82448..83488 - 1041 WP_039296545.1 HipA domain-containing protein -
CVS35_RS00370 83485..83799 - 315 WP_039296542.1 HipA N-terminal domain-containing protein -
CVS35_RS00375 83784..84110 - 327 WP_039296540.1 helix-turn-helix domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-82)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11056.12 Da        Isoelectric Point: 10.3527

>T89340 WP_011091708.1 NZ_CP024956:c79344-79057 [Pectobacterium atrosepticum]
MSYSVKFREDALKEWLKLDKTIQQQFAKKLKKCCENPHIPSAKLRGIKDCYKIKLRASGFRLVYEVIDDVLIIAVVAVGK
RERSGVYHLASERMR

Download         Length: 288 bp

>T89340 NZ_CP024956:c79344-79057 [Pectobacterium atrosepticum]
ATGAGCTATAGCGTCAAATTCAGGGAAGATGCGCTGAAAGAATGGCTAAAACTCGATAAAACCATCCAACAGCAATTTGC
CAAAAAGCTAAAAAAATGCTGCGAAAACCCTCATATTCCTTCGGCAAAGTTACGGGGGATAAAGGATTGCTACAAAATAA
AGCTCCGGGCGTCAGGCTTTCGCTTAGTGTATGAAGTCATTGACGACGTATTGATTATCGCCGTGGTGGCGGTAGGCAAG
CGTGAACGTAGTGGCGTTTATCATCTGGCAAGTGAGCGAATGAGATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9117.47 Da        Isoelectric Point: 4.0637

>AT89340 WP_010281712.1 NZ_CP024956:c79592-79341 [Pectobacterium atrosepticum]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL

Download         Length: 252 bp

>AT89340 NZ_CP024956:c79592-79341 [Pectobacterium atrosepticum]
ATGCCGAATATTATATTGAGTGATACCAGTGCCAGCGTCAGTGAACTGAAAAAGAACCCGATGGCGACGGTCAACGCTGG
CGATGGCCTACCTGTCGCTATTCTGAACCGCAACCAGCCTGCGTTTTATTGCATTCCTGCGGATCTCTACGAAAAAATGC
TGGATGCGCTGGACGACCAGGAACTGGTTAAATTGATCGGTGAACGAAAAAACCAGCCGCTGGTTGACGTGGATTTGGAT
AGTTTCCTATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB Q6DB38

Antitoxin

Source ID Structure
AlphaFold DB A0A0M2EZP0

References