89334

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/YafQ(toxin)
Location 609779..610475 Replicon chromosome
Accession NZ_CP024952
Organism Helicobacter pylori strain B125A

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CV724_RS03035 Protein ID WP_145726921.1
Coordinates 610137..610475 (+) Length 113 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CV724_RS03030 Protein ID WP_145726920.1
Coordinates 609779..610156 (+) Length 126 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CV724_RS03010 605463..605729 + 267 WP_145726918.1 hypothetical protein -
CV724_RS03025 606583..608799 + 2217 WP_145726919.1 outer membrane beta-barrel protein -
CV724_RS03030 609779..610156 + 378 WP_145726920.1 hypothetical protein Antitoxin
CV724_RS03035 610137..610475 + 339 WP_145726921.1 type II toxin-antitoxin system YafQ family toxin Toxin
CV724_RS03040 610478..610753 + 276 WP_145726922.1 hypothetical protein -
CV724_RS03045 610734..611019 + 286 Protein_559 endoribonuclease VapD -
CV724_RS03050 611215..611739 - 525 WP_001135637.1 acyl-CoA thioesterase -
CV724_RS03055 611879..612727 + 849 WP_145726923.1 SDR family oxidoreductase -
CV724_RS03060 612720..613700 + 981 WP_000921454.1 iron ABC transporter permease -
CV724_RS03065 613700..614467 + 768 WP_000242349.1 ABC transporter ATP-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-86)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 113 a.a.        Molecular weight: 13225.63 Da        Isoelectric Point: 9.8467

>T89334 WP_145726921.1 NZ_CP024952:610137-610475 [Helicobacter pylori]
VLKLNLKKSFQKDFDKLLLNGFDDSVLNEVILRKKEPLDPRFQDHALKGKWKPFRECHIKADILLVYLVRDDELILLRLG
SHSELFCKSPTQFITLKPNRLCYNELVFLKRG

Download         Length: 339 bp

>T89334 NZ_CP024952:610137-610475 [Helicobacter pylori]
GTGTTAAAACTCAATCTTAAAAAATCTTTTCAAAAAGATTTTGATAAATTACTTTTGAATGGGTTTGATGATAGCGTTTT
GAATGAAGTCATTCTAAGAAAGAAAGAACCGCTAGATCCACGATTTCAAGATCATGCCTTAAAGGGAAAGTGGAAACCTT
TTAGGGAATGCCACATCAAAGCTGATATTTTGCTTGTGTATTTAGTGCGAGATGATGAGCTGATTTTGTTAAGGTTAGGC
AGTCATAGCGAGCTGTTTTGTAAATCACCCACACAATTTATAACGCTTAAACCAAATCGCTTGTGCTATAATGAGCTGGT
ATTTTTAAAAAGGGGATAA

Antitoxin


Download         Length: 126 a.a.        Molecular weight: 14687.65 Da        Isoelectric Point: 7.1368

>AT89334 WP_145726920.1 NZ_CP024952:609779-610156 [Helicobacter pylori]
MPNTTAEKDYTLYSEKQLFNLIHQLERKIKKMQNDRASFKEKMAKELEKRDQNFKDKIDALNELLQKISQAFDDKRDCCL
GHEIPNIQTQQAMRDALNKETDLIVEDFSSYSDERKKALGVKTQS

Download         Length: 378 bp

>AT89334 NZ_CP024952:609779-610156 [Helicobacter pylori]
ATGCCTAACACCACCGCAGAAAAAGACTACACCCTATACAGCGAAAAACAGCTTTTTAATTTAATCCATCAATTAGAGCG
AAAAATCAAAAAGATGCAAAATGATAGAGCTTCTTTTAAAGAAAAAATGGCTAAAGAATTGGAAAAAAGGGATCAAAACT
TTAAGGATAAAATAGACGCATTAAATGAACTCTTGCAAAAAATCAGCCAAGCTTTTGATGATAAAAGAGATTGCTGTTTG
GGGCATGAAATCCCAAACATTCAGACGCAACAAGCCATGAGAGATGCGCTCAACAAAGAGACCGATTTGATTGTTGAGGA
TTTTTCTAGTTACAGCGATGAAAGAAAAAAGGCGTTAGGTGTTAAAACTCAATCTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References