Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 2040992..2041511 Replicon chromosome
Accession NZ_CP024944
Organism Burkholderia lata strain A05

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CVS37_RS28665 Protein ID WP_122948245.1
Coordinates 2040992..2041225 (-) Length 78 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CVS37_RS28670 Protein ID WP_122948246.1
Coordinates 2041263..2041511 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CVS37_RS28645 2036647..2037345 - 699 WP_122948241.1 MgtC/SapB family protein -
CVS37_RS28650 2037460..2038569 + 1110 WP_122948242.1 AGE family epimerase/isomerase -
CVS37_RS28655 2038542..2040161 - 1620 WP_122948243.1 Tar ligand binding domain-containing protein -
CVS37_RS28660 2040431..2040874 + 444 WP_122948244.1 PaaI family thioesterase -
CVS37_RS28665 2040992..2041225 - 234 WP_122948245.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CVS37_RS28670 2041263..2041511 - 249 WP_122948246.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CVS37_RS28675 2041653..2042705 - 1053 WP_122949649.1 CoA transferase -
CVS37_RS28680 2042792..2043559 - 768 WP_122948247.1 helix-turn-helix domain-containing protein -
CVS37_RS28685 2043694..2044476 + 783 WP_122948248.1 crotonase/enoyl-CoA hydratase family protein -
CVS37_RS28690 2044541..2045761 + 1221 WP_122949650.1 CoA transferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(7-68)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 78 a.a.        Molecular weight: 9100.68 Da        Isoelectric Point: 10.8950

>T89315 WP_122948245.1 NZ_CP024944:c2041225-2040992 [Burkholderia lata]
MLDRTVRDQFKCRLAERLENPRILSAKLRGHPDRYNIKLRSVGYRLVYEVRDSEVLVLVVAVGRRERDAVYLAAMKR

Download         Length: 234 bp

>T89315 NZ_CP024944:c2041225-2040992 [Burkholderia lata]
ATGCTCGATCGCACCGTTCGCGACCAGTTCAAATGCCGGCTCGCCGAGCGGCTCGAGAATCCTCGGATACTGTCTGCAAA
GCTGCGGGGTCATCCGGACCGCTACAACATCAAGCTGCGCAGCGTCGGTTACCGGCTTGTATACGAAGTGCGCGATTCGG
AAGTGCTCGTACTGGTCGTGGCGGTCGGTCGACGTGAGCGCGATGCGGTCTATCTTGCCGCGATGAAGCGTTAG

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 8979.45 Da        Isoelectric Point: 6.9772

>AT89315 WP_122948246.1 NZ_CP024944:c2041511-2041263 [Burkholderia lata]
MPHTILANVIASVSELKRNPMGTVAAGEGFPVAILNRNEPAFYCVPVTTWESMVERLEDIGDNALVDKRTKGKVVKVKLN
DL

Download         Length: 249 bp

>AT89315 NZ_CP024944:c2041511-2041263 [Burkholderia lata]
ATGCCTCATACCATTCTGGCCAACGTTATCGCGAGCGTTTCGGAACTGAAGCGGAACCCGATGGGCACGGTCGCGGCGGG
AGAAGGTTTCCCGGTTGCAATTCTGAATCGCAACGAGCCCGCGTTCTATTGCGTCCCGGTGACGACATGGGAGTCGATGG
TCGAACGTCTGGAGGATATCGGAGACAACGCGCTGGTCGACAAGCGCACCAAGGGGAAAGTCGTCAAAGTCAAGCTGAAC
GACCTTTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References