Detailed information of TA system TA089303

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): shpA-AbkA/BrnT_toxin-BrnA
• Location: 3802651..3803263
• Replicon: chromosome
• Accession: NZ_CP024941
• Organism: Paraburkholderia terricola strain mHS1

Toxin (Protein)

• Gene name: shpA
• Uniprot ID: -
• Locus tag: CUJ90_RS17195
• Protein ID: WP_208645226.1
• Coordinates: 3802958..3803263 (-)
• Length: 102 a.a.

Antitoxin (Protein)

• Gene name: AbkA
• Uniprot ID: -
• Locus tag: CUJ90_RS17190
• Protein ID: WP_073427915.1
• Coordinates: 3802651..3802911 (-)
• Length: 87 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CUJ90_RS17170	3797773..3798525	+	753	WP_073427724.1	5-oxoprolinase subunit PxpA	-
CUJ90_RS17175	3798831..3799577	+	747	WP_073427725.1	DUF969 domain-containing protein	-
CUJ90_RS17180	3799574..3800530	+	957	WP_073427726.1	DUF979 domain-containing protein	-
CUJ90_RS17185	3800756..3802558	+	1803	WP_114163588.1	tetratricopeptide repeat protein	-
CUJ90_RS17190	3802651..3802911	-	261	WP_073427915.1	BrnA antitoxin family protein	Antitoxin
CUJ90_RS17195	3802958..3803263	-	306	WP_208645226.1	BrnT family toxin	Toxin
CUJ90_RS17200	3803450..3804601	-	1152	WP_114163269.1	TraB/GumN family protein	-
CUJ90_RS17205	3804594..3805613	-	1020	WP_073427729.1	ABC transporter ATP-binding protein	-
CUJ90_RS17210	3805610..3806614	-	1005	WP_073427730.1	ABC transporter ATP-binding protein	-
CUJ90_RS17215	3806616..3807533	-	918	WP_073427917.1	ABC transporter permease subunit	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Prophage	-	-	3783366..3805613	22247

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Ribonuclease toxin, BrnT, of type II toxin-antitoxin system (14-91)

Antitoxin

• BrnA antitoxin of type II toxin-antitoxin system (23-77)

Sequences

Toxin

Protein

• Length: 102 a.a.
• Molecular weight: 12070.83 Da
• Isoelectric Point: 10.0219

>T89303 WP_208645226.1 NZ_CP024941:c3803263-3802958 [Paraburkholderia terricola]
MYKRQYGCRVRVEWDEAKNQINIRKHGIDFRDAINVFNHPVLTALDQRNDYGEDRWIAPGWMAAIVGVVVYVERDMDVVR
IISARKATRHEVTRYKRSIWH

Nucleotide

• Length: 306 bp

>T89303 NZ_CP024941:c3803263-3802958 [Paraburkholderia terricola]
ATGTACAAACGTCAATACGGGTGCCGCGTGCGTGTCGAGTGGGATGAAGCCAAGAATCAGATCAACATTCGCAAGCATGG
CATCGACTTCAGAGACGCCATCAACGTGTTCAATCATCCGGTGCTCACCGCATTGGATCAGCGCAACGACTACGGTGAGG
ACCGCTGGATCGCACCCGGTTGGATGGCGGCTATCGTAGGTGTGGTGGTGTACGTCGAGCGCGATATGGACGTGGTCCGC
ATCATCTCGGCGCGCAAGGCCACGAGACACGAAGTCACGCGTTACAAGCGCAGCATCTGGCATTGA

Antitoxin

Protein

• Length: 87 a.a.
• Molecular weight: 9854.22 Da
• Isoelectric Point: 7.3177

>AT89303 WP_073427915.1 NZ_CP024941:c3802911-3802651 [Paraburkholderia terricola]
MSKPTGTDWKRLAKADDAHIDTSDVPELGDDFFEQAELHLPPKQAVTMRLDADVLSWFKEQGAGYQTRINKLLRAYMLAH
QRRALK

Nucleotide

• Length: 261 bp

>AT89303 NZ_CP024941:c3802911-3802651 [Paraburkholderia terricola]
ATGAGCAAACCAACAGGAACAGACTGGAAGCGACTCGCGAAGGCAGACGACGCACATATCGACACAAGCGACGTGCCCGA
GTTGGGTGACGATTTTTTCGAGCAGGCGGAACTGCATCTGCCGCCGAAGCAGGCCGTCACCATGCGCCTCGATGCGGACG
TACTGAGCTGGTTCAAGGAGCAGGGTGCGGGCTATCAGACGCGCATCAACAAGCTGTTGCGCGCCTATATGCTGGCGCAT
CAGCGGCGCGCCCTCAAGTAG