Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mazEF/MazF-MazE
Location 1252283..1252845 Replicon chromosome
Accession NZ_CP024935
Organism Paraburkholderia graminis strain PHS1

Toxin (Protein)


Gene name mazE Uniprot ID -
Locus tag CUJ91_RS23790 Protein ID WP_107709712.1
Coordinates 1252283..1252603 (-) Length 107 a.a.

Antitoxin (Protein)


Gene name mazF Uniprot ID -
Locus tag CUJ91_RS23795 Protein ID WP_107709710.1
Coordinates 1252597..1252845 (-) Length 83 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CUJ91_RS23775 1248948..1249571 + 624 WP_044020130.1 SCO family protein -
CUJ91_RS23780 1249648..1251552 + 1905 WP_167450669.1 RICIN domain-containing protein -
CUJ91_RS23785 1251600..1251992 + 393 WP_035570405.1 hypothetical protein -
CUJ91_RS23790 1252283..1252603 - 321 WP_107709712.1 type II toxin-antitoxin system PemK/MazF family toxin Toxin
CUJ91_RS23795 1252597..1252845 - 249 WP_107709710.1 AbrB/MazE/SpoVT family DNA-binding domain-containing protein Antitoxin
CUJ91_RS23800 1253219..1253410 + 192 WP_153067645.1 hypothetical protein -
CUJ91_RS23810 1254461..1255168 - 708 WP_006052125.1 transcriptional regulator NanR -
CUJ91_RS23815 1255317..1256729 - 1413 WP_114157308.1 four-carbon acid sugar kinase family protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

mRNA interferase PemK-like

(1-103)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 107 a.a.        Molecular weight: 11884.09 Da        Isoelectric Point: 10.3854

>T89289 WP_107709712.1 NZ_CP024935:c1252603-1252283 [Paraburkholderia graminis]
MVVRGEVWLVALDPTLGSEIQKTRPCVVVSPPEMHDHLRTVIVAPMTSKGRPAPFRIPVTFKRKQGLILLDQIRAVDKVR
LVKKEGAIADNTMLDTLRTLQEVFAE

Download         Length: 321 bp

>T89289 NZ_CP024935:c1252603-1252283 [Paraburkholderia graminis]
ATGGTAGTGCGCGGCGAAGTCTGGCTCGTTGCGCTCGATCCGACGCTAGGTAGCGAGATTCAAAAAACGCGGCCCTGTGT
AGTGGTATCGCCGCCTGAGATGCACGACCATCTGCGAACGGTCATCGTTGCACCGATGACTTCGAAAGGGCGCCCTGCGC
CGTTTCGCATACCTGTGACGTTCAAACGGAAACAGGGGTTGATTTTGCTGGATCAGATTCGCGCGGTAGACAAGGTACGA
CTGGTAAAGAAGGAAGGCGCGATTGCCGATAACACAATGTTGGACACCCTGCGTACCTTGCAGGAAGTGTTCGCGGAATA
G

Antitoxin


Download         Length: 83 a.a.        Molecular weight: 9004.20 Da        Isoelectric Point: 4.4929

>AT89289 WP_107709710.1 NZ_CP024935:c1252845-1252597 [Paraburkholderia graminis]
MKTTIRRMGNSQGVLIPKPVLAQLGLENEVEMEVENDAIVLRRPRHKAREGWAEASKALAESGDDALVMGEFGNADDAEL
AW

Download         Length: 249 bp

>AT89289 NZ_CP024935:c1252845-1252597 [Paraburkholderia graminis]
ATGAAAACGACGATTCGCAGGATGGGTAATTCGCAGGGCGTGCTGATTCCAAAGCCCGTCCTTGCGCAGTTGGGATTGGA
GAACGAAGTGGAAATGGAAGTCGAAAACGACGCGATCGTGCTGCGTCGCCCCCGCCATAAGGCTCGCGAAGGCTGGGCTG
AGGCGAGCAAGGCGCTTGCTGAGAGCGGTGACGACGCGCTGGTGATGGGTGAGTTTGGCAACGCCGACGATGCGGAGCTT
GCATGGTAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References