Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pmenTA/darT(toxin)
Location 4130650..4132373 Replicon chromosome
Accession NZ_CP024930
Organism Aeromonas veronii strain Aeromonas veronii X11

Toxin (Protein)


Gene name pmenT Uniprot ID -
Locus tag CVS41_RS18815 Protein ID WP_100654651.1
Coordinates 4130650..4131300 (+) Length 217 a.a.

Antitoxin (Protein)


Gene name pmenA Uniprot ID -
Locus tag CVS41_RS18820 Protein ID WP_100654652.1
Coordinates 4131300..4132373 (+) Length 358 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CVS41_RS19670 4125895..4127247 + 1353 WP_158651148.1 restriction endonuclease subunit S -
CVS41_RS18805 4127244..4128623 + 1380 WP_100654649.1 DUF262 domain-containing protein -
CVS41_RS18810 4128613..4130631 + 2019 WP_100654650.1 DUF262 domain-containing HNH endonuclease family protein -
CVS41_RS18815 4130650..4131300 + 651 WP_100654651.1 DUF4433 domain-containing protein Toxin
CVS41_RS18820 4131300..4132373 + 1074 WP_100654652.1 macro domain-containing protein Antitoxin
CVS41_RS18825 4132598..4135708 + 3111 WP_100654653.1 HsdR family type I site-specific deoxyribonuclease -
CVS41_RS18830 4135705..4136433 + 729 WP_100654654.1 M48 family metallopeptidase -
CVS41_RS18835 4136550..4137353 - 804 WP_158651149.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 4116674..4139760 23086


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

ssDNA thymidine ADP-ribosyltransferase, DarT

(17-216)

Antitoxin

Macro domain

(18-131)


Sequences

Toxin        


Download         Length: 217 a.a.        Molecular weight: 25162.62 Da        Isoelectric Point: 6.6581

>T89285 WP_100654651.1 NZ_CP024930:4130650-4131300 [Aeromonas veronii]
MPYDYSRSLNPEKALIFRIVHRDNLPWILTHGLWAGNAPEQSDTWVHIGLAELINKRAHHPVPLAPFGVLNDYVPFYFTP
FSPMLSNIHSGRGVRQRRNDEILILVSSLHRIAELELAFLFTDSHAYYQWANFYDDLGELNRIDWPILQRRDFKRDPDDP
AKFERYQAEALVHQHCPVEALVGVVCYNEETKAKVEQTMAQLGVARPVYVRSGWYF

Download         Length: 651 bp

>T89285 NZ_CP024930:4130650-4131300 [Aeromonas veronii]
ATGCCATATGACTACAGTCGCAGTCTCAATCCAGAGAAGGCGCTGATCTTTCGTATTGTGCACCGTGACAATCTGCCATG
GATTTTGACCCATGGGCTGTGGGCGGGCAATGCGCCCGAGCAGAGTGATACCTGGGTACATATAGGCTTGGCCGAGTTGA
TCAACAAGCGCGCCCATCATCCGGTGCCACTGGCGCCATTTGGGGTGCTTAACGACTATGTGCCCTTCTACTTCACCCCT
TTCTCCCCAATGCTCAGCAATATCCACTCAGGGAGAGGTGTGCGGCAGCGCCGTAATGACGAGATCCTGATCCTGGTATC
CAGCCTGCATCGCATTGCTGAGCTGGAGCTGGCGTTTTTGTTTACCGACAGCCATGCCTATTATCAATGGGCCAATTTCT
ACGATGACCTGGGTGAACTGAACCGCATCGACTGGCCTATTTTGCAGCGTCGAGACTTCAAGCGTGACCCGGATGACCCT
GCCAAGTTTGAGCGGTATCAGGCAGAGGCGTTGGTTCATCAACACTGCCCCGTTGAGGCATTAGTCGGCGTGGTGTGTTA
CAACGAAGAGACAAAGGCTAAGGTTGAGCAAACGATGGCCCAATTGGGTGTCGCCCGACCGGTTTATGTTCGTTCTGGAT
GGTATTTCTGA

Antitoxin


Download         Length: 358 a.a.        Molecular weight: 40362.52 Da        Isoelectric Point: 7.8908

>AT89285 WP_100654652.1 NZ_CP024930:4131300-4132373 [Aeromonas veronii]
MIRYTTGNLLDAPVEALVNTVNTVGVMGKGIALMFKERFPDNMARYAAACKSGQVTTGKMFITETGELLGPRWIINFPTK
QHWRSPSQMAWIQEGLQDLRHWLVQNHVKSIAIPPLGAGNGGLPWPEVKQAIEEALGDLDIEILLFEPSNQYQNVAKRTG
VEHLTPARALIAELVRRYWFLGMECSLLEIQKLAWFLERFIRQTAPQDPLQLHFTAHHYGPYANNLAHLLNAMDGSYLKS
DKRIPDSKPFDVIWFNDDKKQQLATYLHTEARAYLPALEQAAALIDGFESPYGMELLATVDWLVNQEGCKPTVEALRAGL
IRWPKGGKWAQRKAKLFDDKSLGIALTRLQQSFPAYH

Download         Length: 1074 bp

>AT89285 NZ_CP024930:4131300-4132373 [Aeromonas veronii]
ATGATTCGATACACCACTGGCAACCTGCTAGATGCCCCTGTAGAGGCATTGGTGAATACAGTGAACACCGTTGGTGTCAT
GGGTAAAGGCATTGCGCTGATGTTTAAAGAGCGCTTCCCCGACAACATGGCTCGCTATGCGGCTGCCTGTAAGTCAGGGC
AAGTGACCACTGGCAAGATGTTCATCACCGAAACTGGTGAGCTACTCGGCCCCCGCTGGATCATCAACTTTCCCACCAAG
CAACATTGGCGATCTCCATCCCAGATGGCATGGATTCAGGAAGGCTTACAAGATCTGCGACATTGGCTTGTGCAAAATCA
CGTCAAATCTATCGCCATCCCCCCGCTAGGAGCAGGCAATGGTGGCCTACCATGGCCTGAAGTAAAACAGGCCATTGAAG
AGGCTCTCGGTGATCTGGATATTGAAATCCTGTTGTTTGAACCCAGCAACCAGTACCAAAATGTTGCCAAACGTACTGGC
GTCGAACATCTCACACCAGCCCGCGCCTTGATTGCCGAACTGGTCCGTCGCTACTGGTTTCTTGGCATGGAGTGCAGCCT
GCTGGAAATTCAAAAACTGGCATGGTTTCTGGAGCGCTTTATTCGTCAAACGGCGCCACAAGATCCGCTGCAGTTGCACT
TCACGGCACACCATTACGGGCCTTATGCCAATAATCTAGCCCACTTGCTGAATGCAATGGACGGCAGTTATCTCAAATCA
GATAAGCGGATCCCAGACAGCAAACCCTTTGATGTCATCTGGTTCAATGATGACAAAAAGCAACAACTTGCCACCTATTT
GCATACCGAGGCGCGAGCTTACTTACCCGCGCTGGAGCAAGCTGCTGCGCTTATCGACGGATTTGAGTCCCCCTATGGAA
TGGAGCTGCTAGCAACCGTTGACTGGCTGGTAAACCAAGAAGGATGCAAACCAACCGTAGAGGCGCTGCGGGCAGGACTT
ATCCGTTGGCCCAAAGGTGGCAAATGGGCACAACGTAAGGCCAAGCTGTTCGATGACAAGAGCTTGGGCATTGCCCTGAC
CCGCTTGCAGCAGAGCTTCCCTGCATATCACTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References