89283

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) pasABC/RelE-HTH
Location 3008404..3008872 Replicon chromosome
Accession NZ_CP024923
Organism Sphingomonas sp. Cra20

Toxin (Protein)


Gene name pasB Uniprot ID -
Locus tag CVN68_RS13555 Protein ID WP_100282675.1
Coordinates 3008404..3008670 (-) Length 89 a.a.

Antitoxin (Protein)


Gene name pasA Uniprot ID -
Locus tag CVN68_RS13560 Protein ID WP_100284404.1
Coordinates 3008654..3008872 (-) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CVN68_RS13535 3003548..3004129 + 582 WP_158298882.1 DUF2059 domain-containing protein -
CVN68_RS13540 3004253..3004420 + 168 WP_025560997.1 50S ribosomal protein L33 -
CVN68_RS13545 3004524..3004811 + 288 WP_100282673.1 hypothetical protein -
CVN68_RS13550 3005080..3006975 + 1896 WP_100282674.1 phosphomethylpyrimidine synthase ThiC -
CVN68_RS23235 3007056..3008309 + 1254 WP_158298883.1 hypothetical protein -
CVN68_RS13555 3008404..3008670 - 267 WP_100282675.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CVN68_RS13560 3008654..3008872 - 219 WP_100284404.1 TraY domain-containing protein Antitoxin
CVN68_RS13565 3008985..3009200 + 216 WP_100284405.1 DUF4160 domain-containing protein -
CVN68_RS13570 3009184..3009444 + 261 WP_100282676.1 DUF2442 domain-containing protein -
CVN68_RS13575 3009538..3010479 + 942 WP_100282677.1 hypothetical protein -
CVN68_RS13580 3010538..3011056 + 519 WP_100282678.1 2'-5' RNA ligase family protein -
CVN68_RS13585 3011023..3011460 + 438 WP_100282679.1 VOC family protein -
CVN68_RS13590 3011532..3012008 + 477 WP_100282680.1 DUF1579 domain-containing protein -
CVN68_RS13595 3012420..3012821 + 402 WP_100282681.1 NAD(+)--rifampin ADP-ribosyltransferase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

Relaxosome protein TraY

(4-47)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10206.00 Da        Isoelectric Point: 11.1190

>T89283 WP_100282675.1 NZ_CP024923:c3008670-3008404 [Sphingomonas sp. Cra20]
MAWKIEFLPEAAKELKKLDRTAAARIIRTLAQRIAVLDDPRALGSALVGDHAGYWRWRIGEYRVVARIEDARVLILVVRV
AHRREVYR

Download         Length: 267 bp

>T89283 NZ_CP024923:c3008670-3008404 [Sphingomonas sp. Cra20]
TTGGCCTGGAAGATTGAGTTCCTGCCCGAGGCGGCGAAGGAACTGAAGAAGCTCGACCGGACGGCGGCGGCGCGGATCAT
CAGGACGCTGGCGCAACGGATCGCAGTGCTGGACGACCCCCGCGCGCTGGGCTCAGCGCTGGTGGGGGATCATGCGGGCT
ATTGGCGCTGGCGGATCGGAGAGTATCGCGTGGTGGCGCGGATCGAGGATGCGCGGGTGCTGATCCTGGTGGTGCGCGTG
GCGCATCGACGGGAGGTTTATCGGTGA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8155.10 Da        Isoelectric Point: 4.2075

>AT89283 WP_100284404.1 NZ_CP024923:c3008872-3008654 [Sphingomonas sp. Cra20]
MLAVRLDTETEARLDALAARTGRTKTFYAREAIAAHLDDLEDFYLAEERLRDFRDGDAIPLADLKTELGLED

Download         Length: 219 bp

>AT89283 NZ_CP024923:c3008872-3008654 [Sphingomonas sp. Cra20]
ATGTTGGCAGTACGTCTGGATACCGAGACCGAAGCCCGGCTCGACGCGCTGGCGGCGCGGACGGGGCGTACCAAGACCTT
CTATGCGCGCGAGGCGATTGCGGCGCATCTCGATGATCTCGAGGATTTCTACCTCGCCGAGGAGCGGCTGCGCGATTTCC
GCGACGGCGACGCGATCCCGCTTGCCGATCTGAAGACCGAGCTTGGCCTGGAAGATTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References