Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 5019667..5020110 Replicon chromosome
Accession NZ_CP024901
Organism Photorhabdus laumondii subsp. laumondii strain TT01

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag PluTT01m_RS22020 Protein ID WP_011148391.1
Coordinates 5019886..5020110 (+) Length 75 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID Q7MZJ1
Locus tag PluTT01m_RS22015 Protein ID WP_011148390.1
Coordinates 5019667..5019885 (+) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-54)

Antitoxin

Post-segregation antitoxin CcdA

(2-72)


Sequences

Toxin        


Download         Length: 75 a.a.        Molecular weight: 8681.12 Da        Isoelectric Point: 8.2844

>T89222 WP_011148391.1 NZ_CP024901:5019886-5020110 [Photorhabdus laumondii subsp. laumondii]
MQFVVYQYKRSESKYSMFVDVQRDIIETPERRMAIPLVEAHHFSSKVSRHLFPTSGSQFSSFVPLCCVCMNIFL

Download         Length: 225 bp

>T89222 NZ_CP024901:5019886-5020110 [Photorhabdus laumondii subsp. laumondii]
ATGCAATTTGTTGTTTATCAATACAAACGGAGCGAAAGCAAATACAGTATGTTTGTTGATGTACAACGTGACATCATTGA
AACACCAGAAAGGCGTATGGCTATTCCTTTAGTTGAAGCGCATCATTTTTCAAGCAAGGTGAGTCGTCATCTATTTCCCA
CGTCTGGCTCTCAGTTTTCTTCATTTGTGCCGCTCTGCTGCGTCTGTATGAATATTTTTCTGTAA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8379.39 Da        Isoelectric Point: 8.5552

>AT89222 WP_011148390.1 NZ_CP024901:5019667-5019885 [Photorhabdus laumondii subsp. laumondii]
MKHRVNVTFDKENYLILNSAGVNISGFVNKAMTREAQRIKAESWKADNRKGLEEIAQFIEQYGSFADENRNW

Download         Length: 219 bp

>AT89222 NZ_CP024901:5019667-5019885 [Photorhabdus laumondii subsp. laumondii]
ATGAAACATAGAGTTAACGTAACTTTTGATAAAGAAAATTATCTGATCCTGAATTCAGCCGGTGTAAATATTTCAGGTTT
TGTTAATAAAGCCATGACCAGAGAAGCTCAACGAATCAAAGCTGAAAGTTGGAAAGCAGATAATCGCAAAGGATTGGAAG
AAATTGCTCAATTTATTGAACAATATGGCTCATTTGCTGATGAAAACAGGAACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure
AlphaFold DB A0A6L9JTU9

References