Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 4839416..4839859 Replicon chromosome
Accession NZ_CP024900
Organism Photorhabdus laumondii subsp. laumondii strain DJC

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag PluDJC_RS21330 Protein ID WP_011148391.1
Coordinates 4839635..4839859 (+) Length 75 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag PluDJC_RS21325 Protein ID WP_113049686.1
Coordinates 4839416..4839634 (+) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PluDJC_RS21300 4835174..4836163 - 990 WP_113049684.1 glycosyltransferase -
PluDJC_RS21305 4836543..4837739 + 1197 WP_011148386.1 aspartyl protease family protein -
PluDJC_RS21310 4837909..4838520 - 612 WP_011148387.1 hypothetical protein -
PluDJC_RS21315 4838654..4838890 - 237 WP_113049685.1 helix-turn-helix domain-containing protein -
PluDJC_RS21320 4839040..4839249 + 210 WP_011148389.1 helix-turn-helix domain-containing protein -
PluDJC_RS21325 4839416..4839634 + 219 WP_113049686.1 type II toxin-antitoxin system antitoxin CcdA Antitoxin
PluDJC_RS21330 4839635..4839859 + 225 WP_011148391.1 CcdB family protein Toxin
PluDJC_RS21335 4839805..4840794 - 990 WP_011148392.1 AraC family transcriptional regulator -
PluDJC_RS21340 4840909..4841550 + 642 WP_011148393.1 HD domain-containing protein -
PluDJC_RS21345 4841786..4842022 - 237 WP_011148394.1 helix-turn-helix domain-containing protein -
PluDJC_RS21350 4842374..4843039 - 666 WP_109792001.1 GntR family transcriptional regulator -
PluDJC_RS21355 4843606..4844334 + 729 WP_011148396.1 DUF969 domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-54)

Antitoxin

Post-segregation antitoxin CcdA

(2-72)


Sequences

Toxin        


Download         Length: 75 a.a.        Molecular weight: 8681.12 Da        Isoelectric Point: 8.2844

>T89187 WP_011148391.1 NZ_CP024900:4839635-4839859 [Photorhabdus laumondii subsp. laumondii]
MQFVVYQYKRSESKYSMFVDVQRDIIETPERRMAIPLVEAHHFSSKVSRHLFPTSGSQFSSFVPLCCVCMNIFL

Download         Length: 225 bp

>T89187 NZ_CP024900:4839635-4839859 [Photorhabdus laumondii subsp. laumondii]
ATGCAATTTGTTGTTTATCAATATAAACGGAGCGAAAGCAAATACAGTATGTTTGTTGATGTACAACGTGACATCATTGA
AACACCAGAAAGGCGTATGGCTATTCCTTTAGTTGAAGCGCATCATTTTTCAAGCAAGGTGAGTCGTCATCTATTTCCCA
CGTCTGGCTCTCAGTTTTCTTCATTTGTGCCGCTCTGCTGCGTCTGTATGAATATTTTTCTGTAA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8407.45 Da        Isoelectric Point: 8.5552

>AT89187 WP_113049686.1 NZ_CP024900:4839416-4839634 [Photorhabdus laumondii subsp. laumondii]
MKHRVNVTFDKENYLILNSAGVNISGFVNKVMTREAQRIKAESWKADNRKGLEEIAQFIEQYGSFADENRNW

Download         Length: 219 bp

>AT89187 NZ_CP024900:4839416-4839634 [Photorhabdus laumondii subsp. laumondii]
ATGAAACATAGAGTTAACGTAACTTTTGATAAAGAAAATTATCTGATCCTGAATTCAGCCGGTGTAAATATTTCAGGTTT
TGTTAATAAAGTCATGACCAGAGAAGCTCAACGAATCAAAGCTGAAAGTTGGAAAGCAGATAATCGCAAAGGATTGGAAG
AAATTGCTCAATTTATTGAACAATATGGCTCATTTGCTGATGAAAACAGGAACTGGTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References