Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 4011909..4012572 Replicon chromosome
Accession NZ_CP024900
Organism Photorhabdus laumondii subsp. laumondii strain DJC

Toxin (Protein)


Gene name cptA Uniprot ID Q7N1C2
Locus tag PluDJC_RS17595 Protein ID WP_011147734.1
Coordinates 4011909..4012325 (-) Length 139 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID Q7N1C1
Locus tag PluDJC_RS17600 Protein ID WP_011147735.1
Coordinates 4012306..4012572 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PluDJC_RS17575 4007886..4009619 - 1734 WP_011147730.1 single-stranded-DNA-specific exonuclease RecJ -
PluDJC_RS17580 4009619..4010326 - 708 WP_011147731.1 bifunctional protein-disulfide isomerase/oxidoreductase DsbC -
PluDJC_RS17585 4010350..4011261 - 912 WP_011147732.1 site-specific tyrosine recombinase XerD -
PluDJC_RS17590 4011369..4011887 + 519 WP_041380273.1 flavodoxin FldB -
PluDJC_RS17595 4011909..4012325 - 417 WP_011147734.1 protein YgfX Toxin
PluDJC_RS17600 4012306..4012572 - 267 WP_011147735.1 FAD assembly factor SdhE Antitoxin
PluDJC_RS17605 4012750..4013739 + 990 WP_011147736.1 tRNA-modifying protein YgfZ -
PluDJC_RS17610 4013751..4014356 + 606 WP_011147737.1 HD domain-containing protein -
PluDJC_RS17615 4015288..4016592 - 1305 WP_011147738.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(3-135)

Antitoxin

Flavinator of succinate dehydrogenase

(7-79)


Sequences

Toxin        


Download         Length: 139 a.a.        Molecular weight: 16363.34 Da        Isoelectric Point: 10.1464

>T89182 WP_011147734.1 NZ_CP024900:c4012325-4011909 [Photorhabdus laumondii subsp. laumondii]
VVLWKCDLRVSWHTQLISTCVHGAIALIVLFAPWPADDAIFWIFWLPLVLLIIASWGRSQKNIRKSQGLLVLLSDNKLQW
KKHEWQIIRRPWLCRYGVLITAQSFYNQKKIRLWVASDGMPQDEWRNINQLLLQYPDI

Download         Length: 417 bp

>T89182 NZ_CP024900:c4012325-4011909 [Photorhabdus laumondii subsp. laumondii]
GTGGTCCTGTGGAAGTGTGATCTCAGGGTATCTTGGCATACCCAGCTAATTTCTACCTGTGTTCATGGTGCAATAGCGCT
TATCGTACTATTTGCTCCGTGGCCTGCGGATGACGCTATTTTCTGGATTTTCTGGCTTCCTTTGGTACTGTTGATTATTG
CCAGTTGGGGGCGTAGCCAGAAAAATATCCGTAAATCTCAAGGGCTTTTAGTTCTTCTCAGTGATAATAAGTTGCAATGG
AAGAAGCATGAGTGGCAAATTATCCGGCGGCCGTGGTTGTGTCGTTATGGCGTATTAATTACGGCTCAATCTTTTTATAA
CCAGAAAAAAATCCGTTTATGGGTCGCATCCGATGGTATGCCACAGGATGAATGGAGGAATATTAATCAACTGTTGTTGC
AATATCCTGATATCTGA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10645.25 Da        Isoelectric Point: 5.7258

>AT89182 WP_011147735.1 NZ_CP024900:c4012572-4012306 [Photorhabdus laumondii subsp. laumondii]
MDIDNKARIHWACRRGMRELDISIMPFFKYEYDSLSDDDKRLFIRLLACADPDLFNWLMNHGRPEDEELFRMIKLIQNRN
KDRGPVEV

Download         Length: 267 bp

>AT89182 NZ_CP024900:c4012572-4012306 [Photorhabdus laumondii subsp. laumondii]
ATGGATATTGATAATAAAGCGCGTATTCATTGGGCATGTCGGCGTGGAATGCGTGAGCTGGATATTTCAATTATGCCGTT
TTTTAAGTATGAATATGACTCACTCAGTGATGATGATAAACGACTTTTTATTCGCTTACTTGCATGTGCTGATCCTGATC
TATTCAACTGGCTAATGAATCATGGGCGTCCAGAAGATGAAGAGTTATTTCGCATGATTAAACTTATTCAGAATAGAAAT
AAAGATCGTGGTCCTGTGGAAGTGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A6L9JK22

Antitoxin

Source ID Structure
AlphaFold DB A0A6L9JKF1

References