Detailed information of TA system TA089173

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/Txe-RelB
• Location: 2645241..2645647
• Replicon: chromosome
• Accession: NZ_CP024900
• Organism: Photorhabdus laumondii subsp. laumondii strain DJC

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: PluDJC_RS12140
• Protein ID: WP_071824109.1
• Coordinates: 2645241..2645333 (-)
• Length: 31 a.a.

Antitoxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: PluDJC_RS12145
• Protein ID: WP_011146529.1
• Coordinates: 2645393..2645647 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
PluDJC_RS12115	2641511..2642830	+	1320	WP_011146524.1	xylose isomerase	-
PluDJC_RS12120	2643250..2643822	+	573	WP_011146525.1	hypothetical protein	-
PluDJC_RS12125	2644114..2644488	+	375	WP_041380079.1	VOC family protein	-
PluDJC_RS12130	2644576..2644815	+	240	WP_011146527.1	type II toxin-antitoxin system CcdA family antitoxin	-
PluDJC_RS12135	2644817..2645122	+	306	WP_011146528.1	CcdB family protein	-
PluDJC_RS12140	2645241..2645333	-	93	WP_071824109.1	type II toxin-antitoxin system YoeB family toxin	Toxin
PluDJC_RS12145	2645393..2645647	-	255	WP_011146529.1	type II toxin-antitoxin system prevent-host-death family antitoxin	Antitoxin
PluDJC_RS12150	2645703..2646116	-	414	WP_113049478.1	Exc2 family lipoprotein	-
PluDJC_RS12155	2646168..2646368	-	201	WP_011146531.1	DUF1778 domain-containing protein	-
PluDJC_RS12160	2646513..2650124	-	3612	WP_109791561.1	transporter substrate-binding domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin YoeB (1-28)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (1-74)

Sequences

Toxin

Protein

• Length: 31 a.a.
• Molecular weight: 3720.27 Da
• Isoelectric Point: 9.7449

>T89173 WP_071824109.1 NZ_CP024900:c2645333-2645241 [Photorhabdus laumondii subsp. laumondii]
MSGYWSRRINREHRLVYKVTDDAIIIVQHY

Nucleotide

• Length: 93 bp

>T89173 NZ_CP024900:c2645333-2645241 [Photorhabdus laumondii subsp. laumondii]
TTGTCGGGTTATTGGTCTAGACGTATTAATCGAGAGCATCGTCTGGTTTACAAGGTAACAGATGATGCAATCATTATCGT
GCAGCACTATTAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9422.72 Da
• Isoelectric Point: 6.4794

>AT89173 WP_011146529.1 NZ_CP024900:c2645647-2645393 [Photorhabdus laumondii subsp. laumondii]
MDTINYSAFRTHFASPLDKVNDNHKPILITHQNGKPAIALRLEDFQAYEETAYLMASPKNAAHLNQAIAEVEAGRMIEKG
LLKE

Nucleotide

• Length: 255 bp

>AT89173 NZ_CP024900:c2645647-2645393 [Photorhabdus laumondii subsp. laumondii]
ATGGACACAATAAACTATTCAGCATTTAGAACTCACTTCGCCAGCCCCTTAGATAAAGTGAACGACAATCACAAGCCAAT
TCTGATTACTCATCAGAATGGCAAGCCAGCGATCGCCCTACGTTTGGAAGATTTTCAAGCCTACGAAGAAACAGCCTATT
TAATGGCTAGCCCGAAAAACGCGGCACATTTAAATCAGGCAATTGCTGAAGTGGAAGCAGGGAGAATGATTGAAAAAGGG
CTATTGAAAGAATGA