Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 281420..281954 Replicon chromosome
Accession NZ_CP024900
Organism Photorhabdus laumondii subsp. laumondii strain DJC

Toxin (Protein)


Gene name relE Uniprot ID Q7N9Q9
Locus tag PluDJC_RS01365 Protein ID WP_011144654.1
Coordinates 281664..281954 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID Q7N9R0
Locus tag PluDJC_RS01360 Protein ID WP_011144653.1
Coordinates 281420..281674 (+) Length 85 a.a.

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PluDJC_RS01335 276764..276955 + 192 Protein_254 hypothetical protein -
PluDJC_RS01340 277632..278375 + 744 WP_011144649.1 class I SAM-dependent methyltransferase -
PluDJC_RS01345 278651..279058 - 408 WP_011144650.1 type II toxin-antitoxin system RelE/ParE family toxin -
PluDJC_RS01350 279061..279330 - 270 WP_011144651.1 type II toxin-antitoxin system Phd/YefM family antitoxin -
PluDJC_RS01355 280246..281013 + 768 WP_011144652.1 Fic family protein -
PluDJC_RS01360 281420..281674 + 255 WP_011144653.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
PluDJC_RS01365 281664..281954 + 291 WP_011144654.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
PluDJC_RS01375 282943..283203 - 261 WP_011144656.1 hypothetical protein -
PluDJC_RS01380 283297..283575 - 279 WP_011144657.1 hypothetical protein -
PluDJC_RS01385 284231..286312 - 2082 WP_113049662.1 ATP-dependent DNA helicase RecG -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.



Sequences


Toxin        


Download         Length: 97 a.a.        Molecular weight: 11349.32 Da        Isoelectric Point: 9.9557

>T89161 WP_011144654.1 NZ_CP024900:281664-281954 [Photorhabdus laumondii subsp. laumondii]
MIFNIDFDERALKEWYKLDQSIRDQFKKKLRKLQNNPYIDSARLHGNLAGCFKIKLRSSGFRLVYQVIEEEIVILVIAVG
KREDAKTYEIACKRIV

Download         Length: 291 bp

>T89161 NZ_CP024900:281664-281954 [Photorhabdus laumondii subsp. laumondii]
ATGATATTTAATATCGATTTCGACGAACGAGCCCTGAAAGAGTGGTACAAACTGGATCAGAGCATACGCGACCAATTTAA
AAAGAAGCTACGGAAGTTACAGAACAATCCCTATATTGATTCAGCCAGATTACACGGTAATCTGGCTGGCTGCTTTAAAA
TTAAACTCCGTTCTTCAGGCTTTCGTCTGGTTTACCAAGTGATAGAAGAAGAGATCGTAATATTGGTGATCGCTGTTGGT
AAACGGGAAGATGCGAAAACTTATGAAATAGCTTGTAAACGAATTGTATAA

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9774.19 Da        Isoelectric Point: 4.8485

>AT89161 WP_011144653.1 NZ_CP024900:281420-281674 [Photorhabdus laumondii subsp. laumondii]
MSTIQIRVDEELKKSAYQTFEKLNLSPSDALRLFLRYVVENEKLPFTEVSVMVADHDEDADILAVVRDRLKNPARRIRVN
LDDI

Download         Length: 255 bp

>AT89161 NZ_CP024900:281420-281674 [Photorhabdus laumondii subsp. laumondii]
ATGAGTACTATTCAGATCAGAGTTGATGAAGAACTTAAAAAAAGTGCGTATCAGACATTTGAGAAACTGAACTTATCGCC
ATCTGATGCGCTACGTCTCTTTCTGCGATATGTTGTGGAGAATGAAAAGCTGCCGTTCACTGAAGTTTCCGTTATGGTGG
CAGATCATGATGAAGATGCAGACATCTTAGCAGTGGTACGTGACCGTCTTAAAAATCCCGCTAGACGTATCAGGGTAAAC
CTTGATGATATTTAA

Similar Proteins


Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures


Toxin

Source ID Structure
AlphaFold DB A0A6L9JHV9


Antitoxin

Source ID Structure
AlphaFold DB A0A6L9JHC8

References