Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/ParE-RelB |
Location | 281420..281954 | Replicon | chromosome |
Accession | NZ_CP024900 | ||
Organism | Photorhabdus laumondii subsp. laumondii strain DJC |
Toxin (Protein)
Gene name | relE | Uniprot ID | Q7N9Q9 |
Locus tag | PluDJC_RS01365 | Protein ID | WP_011144654.1 |
Coordinates | 281664..281954 (+) | Length | 97 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | Q7N9R0 |
Locus tag | PluDJC_RS01360 | Protein ID | WP_011144653.1 |
Coordinates | 281420..281674 (+) | Length | 85 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
PluDJC_RS01335 | 276764..276955 | + | 192 | Protein_254 | hypothetical protein | - |
PluDJC_RS01340 | 277632..278375 | + | 744 | WP_011144649.1 | class I SAM-dependent methyltransferase | - |
PluDJC_RS01345 | 278651..279058 | - | 408 | WP_011144650.1 | type II toxin-antitoxin system RelE/ParE family toxin | - |
PluDJC_RS01350 | 279061..279330 | - | 270 | WP_011144651.1 | type II toxin-antitoxin system Phd/YefM family antitoxin | - |
PluDJC_RS01355 | 280246..281013 | + | 768 | WP_011144652.1 | Fic family protein | - |
PluDJC_RS01360 | 281420..281674 | + | 255 | WP_011144653.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
PluDJC_RS01365 | 281664..281954 | + | 291 | WP_011144654.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
PluDJC_RS01375 | 282943..283203 | - | 261 | WP_011144656.1 | hypothetical protein | - |
PluDJC_RS01380 | 283297..283575 | - | 279 | WP_011144657.1 | hypothetical protein | - |
PluDJC_RS01385 | 284231..286312 | - | 2082 | WP_113049662.1 | ATP-dependent DNA helicase RecG | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 11349.32 Da Isoelectric Point: 9.9557
>T89161 WP_011144654.1 NZ_CP024900:281664-281954 [Photorhabdus laumondii subsp. laumondii]
MIFNIDFDERALKEWYKLDQSIRDQFKKKLRKLQNNPYIDSARLHGNLAGCFKIKLRSSGFRLVYQVIEEEIVILVIAVG
KREDAKTYEIACKRIV
MIFNIDFDERALKEWYKLDQSIRDQFKKKLRKLQNNPYIDSARLHGNLAGCFKIKLRSSGFRLVYQVIEEEIVILVIAVG
KREDAKTYEIACKRIV
Download Length: 291 bp
>T89161 NZ_CP024900:281664-281954 [Photorhabdus laumondii subsp. laumondii]
ATGATATTTAATATCGATTTCGACGAACGAGCCCTGAAAGAGTGGTACAAACTGGATCAGAGCATACGCGACCAATTTAA
AAAGAAGCTACGGAAGTTACAGAACAATCCCTATATTGATTCAGCCAGATTACACGGTAATCTGGCTGGCTGCTTTAAAA
TTAAACTCCGTTCTTCAGGCTTTCGTCTGGTTTACCAAGTGATAGAAGAAGAGATCGTAATATTGGTGATCGCTGTTGGT
AAACGGGAAGATGCGAAAACTTATGAAATAGCTTGTAAACGAATTGTATAA
ATGATATTTAATATCGATTTCGACGAACGAGCCCTGAAAGAGTGGTACAAACTGGATCAGAGCATACGCGACCAATTTAA
AAAGAAGCTACGGAAGTTACAGAACAATCCCTATATTGATTCAGCCAGATTACACGGTAATCTGGCTGGCTGCTTTAAAA
TTAAACTCCGTTCTTCAGGCTTTCGTCTGGTTTACCAAGTGATAGAAGAAGAGATCGTAATATTGGTGATCGCTGTTGGT
AAACGGGAAGATGCGAAAACTTATGAAATAGCTTGTAAACGAATTGTATAA
Antitoxin
Download Length: 85 a.a. Molecular weight: 9774.19 Da Isoelectric Point: 4.8485
>AT89161 WP_011144653.1 NZ_CP024900:281420-281674 [Photorhabdus laumondii subsp. laumondii]
MSTIQIRVDEELKKSAYQTFEKLNLSPSDALRLFLRYVVENEKLPFTEVSVMVADHDEDADILAVVRDRLKNPARRIRVN
LDDI
MSTIQIRVDEELKKSAYQTFEKLNLSPSDALRLFLRYVVENEKLPFTEVSVMVADHDEDADILAVVRDRLKNPARRIRVN
LDDI
Download Length: 255 bp
>AT89161 NZ_CP024900:281420-281674 [Photorhabdus laumondii subsp. laumondii]
ATGAGTACTATTCAGATCAGAGTTGATGAAGAACTTAAAAAAAGTGCGTATCAGACATTTGAGAAACTGAACTTATCGCC
ATCTGATGCGCTACGTCTCTTTCTGCGATATGTTGTGGAGAATGAAAAGCTGCCGTTCACTGAAGTTTCCGTTATGGTGG
CAGATCATGATGAAGATGCAGACATCTTAGCAGTGGTACGTGACCGTCTTAAAAATCCCGCTAGACGTATCAGGGTAAAC
CTTGATGATATTTAA
ATGAGTACTATTCAGATCAGAGTTGATGAAGAACTTAAAAAAAGTGCGTATCAGACATTTGAGAAACTGAACTTATCGCC
ATCTGATGCGCTACGTCTCTTTCTGCGATATGTTGTGGAGAATGAAAAGCTGCCGTTCACTGAAGTTTCCGTTATGGTGG
CAGATCATGATGAAGATGCAGACATCTTAGCAGTGGTACGTGACCGTCTTAAAAATCCCGCTAGACGTATCAGGGTAAAC
CTTGATGATATTTAA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A6L9JHV9 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A6L9JHC8 |