Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) ykfI-yfjZ/CbtA-CbeA
Location 152796..153484 Replicon chromosome
Accession NZ_CP024900
Organism Photorhabdus laumondii subsp. laumondii strain DJC

Toxin (Protein)


Gene name ykfI Uniprot ID -
Locus tag PluDJC_RS00755 Protein ID WP_011144541.1
Coordinates 153197..153484 (+) Length 96 a.a.

Antitoxin (Protein)


Gene name yfjZ Uniprot ID -
Locus tag PluDJC_RS00750 Protein ID WP_109791246.1
Coordinates 152796..153122 (+) Length 109 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
PluDJC_RS00720 148554..148948 - 395 Protein_136 VOC family protein -
PluDJC_RS00725 149143..149310 + 168 WP_082302939.1 DNA alkylation repair protein -
PluDJC_RS00730 149354..149950 - 597 WP_011144536.1 hypothetical protein -
PluDJC_RS00735 150230..151360 + 1131 WP_113049752.1 ISAs1 family transposase -
PluDJC_RS00740 151669..152142 + 474 WP_041379856.1 hypothetical protein -
PluDJC_RS00745 152280..152747 + 468 WP_109791245.1 DNA repair protein RadC -
PluDJC_RS00750 152796..153122 + 327 WP_109791246.1 type IV toxin-antitoxin system YeeU family antitoxin Antitoxin
PluDJC_RS00755 153197..153484 + 288 WP_011144541.1 TA system toxin CbtA family protein Toxin
PluDJC_RS00760 153598..154431 + 834 WP_011144542.1 DUF4942 domain-containing protein -
PluDJC_RS00765 154519..155556 + 1038 WP_011144543.1 virulence RhuM family protein -
PluDJC_RS00770 155686..155820 + 135 Protein_146 virulence RhuM family protein -
PluDJC_RS26190 156072..156242 + 171 WP_157852154.1 hypothetical protein -
PluDJC_RS00775 156221..156991 - 771 WP_011144544.1 IclR family transcriptional regulator -
PluDJC_RS00780 157136..157636 + 501 WP_011144545.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

CbtA toxin of type IV toxin-antitoxin system

(1-90)

Antitoxin

Antitoxin CbeA

(7-107)


Sequences

Toxin        


Download         Length: 96 a.a.        Molecular weight: 11027.57 Da        Isoelectric Point: 6.8689

>T89159 WP_011144541.1 NZ_CP024900:153197-153484 [Photorhabdus laumondii subsp. laumondii]
VLVWQTLLTRLLEQHYGLTLNDTPFSDETVIQEHINAGITLADAVNFLVEKYELVRIDLRRFNCQEQSPYLRAVDILRAR
QATGLLRQSHHPSTR

Download         Length: 288 bp

>T89159 NZ_CP024900:153197-153484 [Photorhabdus laumondii subsp. laumondii]
GTGCTTGTCTGGCAAACTCTACTTACACGTCTGCTGGAGCAACATTATGGCCTCACCCTGAATGACACGCCGTTCAGCGA
TGAAACTGTTATTCAGGAACATATCAACGCTGGTATTACATTGGCTGATGCCGTTAACTTTTTGGTAGAAAAGTACGAAC
TGGTTCGTATCGACCTCAGGAGGTTTAACTGTCAGGAGCAATCACCTTATCTTCGGGCTGTAGATATTTTACGGGCAAGG
CAAGCAACCGGCCTTTTGCGGCAAAGCCATCATCCTTCAACTCGCTGA

Antitoxin


Download         Length: 109 a.a.        Molecular weight: 12532.16 Da        Isoelectric Point: 5.5236

>AT89159 WP_109791246.1 NZ_CP024900:152796-153122 [Photorhabdus laumondii subsp. laumondii]
MEKNDNPEWGLRYDLMPRFTARLVQEGNRLHYLADRAGITGTFNEEECHQLNAAFPHFIKQMELMLLSGELNPRDAHRVT
LYHNELTCEADTLGSCGYVYIAIYPTQR

Download         Length: 327 bp

>AT89159 NZ_CP024900:152796-153122 [Photorhabdus laumondii subsp. laumondii]
ATGGAAAAAAACGATAACCCTGAATGGGGGCTTCGGTACGATTTAATGCCTCGCTTTACCGCAAGGTTAGTACAGGAAGG
CAATCGACTACATTATTTAGCTGACCGCGCCGGGATAACTGGCACTTTCAATGAGGAAGAGTGCCACCAACTGAATGCCG
CATTTCCACACTTTATTAAACAGATGGAGCTGATGCTGCTCTCTGGTGAGCTTAACCCCCGCGATGCACACCGTGTAACG
CTGTACCACAACGAACTGACCTGTGAAGCGGATACGCTCGGTAGCTGTGGCTACGTTTACATCGCTATCTATCCCACTCA
ACGTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References