Detailed information of TA system TA089155

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/RelE-Phd
• Location: 153391..153944
• Replicon: plasmid pYYL1.1
• Accession: NZ_CP024892
• Organism: Rhodococcus ruber strain YYL

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: CSW53_RS27095
• Protein ID: WP_102032124.1
• Coordinates: 153391..153672 (-)
• Length: 94 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: A0A8D4G1J8
• Locus tag: CSW53_RS27100
• Protein ID: WP_017682293.1
• Coordinates: 153669..153944 (-)
• Length: 92 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CSW53_RS27080	149577..149768	+	192	WP_102032123.1	hypothetical protein	-
CSW53_RS27085	149805..150429	+	625	Protein_126	Fic family protein	-
CSW53_RS27090	151117..152688	+	1572	WP_029547282.1	IS1634 family transposase	-
CSW53_RS27095	153391..153672	-	282	WP_102032124.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CSW53_RS27100	153669..153944	-	276	WP_017682293.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
CSW53_RS27105	154284..154490	-	207	WP_102032125.1	hypothetical protein	-
CSW53_RS27110	156162..156353	+	192	WP_102032186.1	hypothetical protein	-
CSW53_RS27115	156435..157994	+	1560	WP_102032126.1	serine hydrolase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Non-Mobilizable plasmid	-	-	1..236354	236354

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (37-91)

Antitoxin

• Type II toxin-antitoxin system, antitoxin Phd/YefM (3-73)

Sequences

Toxin

Protein

• Length: 94 a.a.
• Molecular weight: 10604.15 Da
• Isoelectric Point: 10.0198

>T89155 WP_102032124.1 NZ_CP024892:c153672-153391 [Rhodococcus ruber]
MTDEAPEPYDVAIASPARRALSRLPGRIVHAVVEFISGPLAENPHRLSKPLRNDLAGLRSARRGDYRILLRIYDDHRTIL
IVDIDHRAHIYRS

Nucleotide

• Length: 282 bp

>T89155 NZ_CP024892:c153672-153391 [Rhodococcus ruber]
ATGACCGACGAGGCGCCGGAACCCTACGACGTCGCGATCGCCTCACCGGCCCGCCGGGCCCTGTCCCGATTACCGGGACG
GATCGTGCATGCGGTCGTCGAGTTCATCTCCGGCCCACTGGCGGAGAATCCGCACCGGCTGAGCAAACCGCTGCGCAACG
ATCTCGCAGGCCTGCGCAGTGCCCGCCGCGGCGACTACCGCATCCTGCTCCGGATTTACGACGACCACCGCACCATCCTC
ATCGTCGACATCGACCACCGCGCCCACATCTACCGATCCTGA

Antitoxin

Protein

• Length: 92 a.a.
• Molecular weight: 9733.89 Da
• Isoelectric Point: 4.8210

>AT89155 WP_017682293.1 NZ_CP024892:c153944-153669 [Rhodococcus ruber]
VTTVPLGEAKDKLSALVDSAEATHDIITITRHGKPAAVLMSADDLESLHETIYWLSRPGTAESVAVADREYAAGRTASLD
ELRAEHGLPPR

Nucleotide

• Length: 276 bp

>AT89155 NZ_CP024892:c153944-153669 [Rhodococcus ruber]
GTGACGACGGTACCGCTCGGCGAAGCCAAGGACAAGCTCTCGGCGCTGGTGGACAGTGCCGAAGCCACGCACGACATCAT
CACCATCACCCGGCACGGCAAACCGGCCGCGGTCCTGATGTCGGCCGACGATCTGGAATCACTGCACGAGACGATCTACT
GGCTGTCTCGGCCCGGCACCGCCGAGTCGGTCGCGGTCGCCGACCGCGAGTACGCCGCCGGCCGAACCGCCTCGCTCGAC
GAGCTGCGCGCCGAGCACGGCCTGCCGCCCCGATGA