Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4839037..4839175 Replicon chromosome
Accession NZ_CP024885
Organism Klebsiella aerogenes strain AR_0009

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4839037..4839140 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4839037..4839175 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM336_RS24320 4834254..4836590 + 2337 WP_032716232.1 hypothetical protein -
AM336_RS24325 4836626..4837090 + 465 WP_196796173.1 siphovirus Gp157 family protein -
AM336_RS24330 4837120..4837512 + 393 WP_125961766.1 hypothetical protein -
AM336_RS24335 4837579..4837851 + 273 WP_071609883.1 excisionase -
AM336_RS24340 4837826..4838905 + 1080 WP_032708609.1 phage integrase Arm DNA-binding domain-containing protein -
- 4839037..4839140 - 104 - - Toxin
- 4839037..4839175 + 139 - - Antitoxin
AM336_RS24345 4839297..4839638 - 342 WP_015366010.1 YebY family protein -
AM336_RS24350 4839652..4840521 - 870 WP_032705951.1 copper homeostasis membrane protein CopD -
AM336_RS24355 4840525..4840899 - 375 WP_015366008.1 CopC domain-containing protein YobA -
AM336_RS24360 4841034..4841264 + 231 WP_015366007.1 DNA polymerase III subunit theta -
AM336_RS24365 4841344..4842003 + 660 WP_015366006.1 exodeoxyribonuclease X -
AM336_RS24370 4842006..4844066 - 2061 WP_032705952.1 oligopeptidase B -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 4780856..4844066 63210


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T89086 NZ_CP024885:c4839140-4839037 [Klebsiella aerogenes]
GGCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 139 bp

>AT89086 NZ_CP024885:4839037-4839175 [Klebsiella aerogenes]
AAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCAT
TAATGCAGGCTAAGTCGCCTTGCCTTATAAGAATAGTTGACTGTGACAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References