Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4707188..4707459 Replicon chromosome
Accession NZ_CP024859
Organism Escherichia coli strain AR_0014

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4707318..4707421 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4707188..4707459 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
AM341_RS23985 4703743..4704405 - 663 WP_000944256.1 exodeoxyribonuclease X -
AM341_RS23990 4704429..4705085 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
AM341_RS23995 4705187..4705417 - 231 WP_000916763.1 DNA polymerase III subunit theta -
AM341_RS24000 4705556..4705930 + 375 WP_000168747.1 CopC domain-containing protein YobA -
AM341_RS24005 4705934..4706806 + 873 WP_000879289.1 copper homeostasis membrane protein CopD -
AM341_RS24010 4706819..4707160 + 342 WP_000976476.1 YebY family protein -
- 4707188..4707459 - 272 - - Antitoxin
- 4707318..4707421 + 104 - - Toxin
AM341_RS24015 4707556..4708212 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
AM341_RS24020 4708213..4708404 - 192 WP_000457842.1 YebW family protein -
AM341_RS24025 4708509..4708745 - 237 WP_001295499.1 DUF1480 family protein -
AM341_RS24030 4708863..4710302 - 1440 WP_001352260.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T88917 NZ_CP024859:4707318-4707421 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT88917 NZ_CP024859:c4707459-4707188 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References