Detailed information of TA system TA088808

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): tad-ata/COG5606-COG4679
• Location: 3538175..3538838
• Replicon: chromosome
• Accession: NZ_CP024842
• Organism: Pectobacterium versatile strain 3-2

Toxin (Protein)

• Gene name: tad
• Uniprot ID: -
• Locus tag: OA04_RS16155
• Protein ID: WP_103940843.1
• Coordinates: 3538175..3538519 (+)
• Length: 115 a.a.

Antitoxin (Protein)

• Gene name: ata
• Uniprot ID: -
• Locus tag: OA04_RS16160
• Protein ID: WP_103940841.1
• Coordinates: 3538521..3538838 (+)
• Length: 106 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OA04_RS16135	3534973..3535281	-	309	WP_107333253.1	hypothetical protein	-
OA04_RS16140	3535321..3535941	-	621	WP_107333254.1	FMN-dependent NADH-azoreductase	-
OA04_RS16145	3535976..3536749	-	774	WP_107333255.1	alpha/beta hydrolase	-
OA04_RS16150	3536915..3537943	+	1029	WP_107333256.1	helix-turn-helix domain-containing protein	-
OA04_RS16155	3538175..3538519	+	345	WP_103940843.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
OA04_RS16160	3538521..3538838	+	318	WP_103940841.1	helix-turn-helix domain-containing protein	Antitoxin
OA04_RS16165	3539052..3539267	-	216	WP_010279992.1	helix-turn-helix domain-containing protein	-
OA04_RS16175	3539853..3540431	-	579	WP_103183417.1	hypothetical protein	-
OA04_RS16180	3540901..3541227	+	327	WP_164498029.1	type II toxin-antitoxin system RelE/ParE family toxin	-
OA04_RS16185	3541232..3541570	+	339	WP_010279998.1	putative addiction module antidote protein	-
OA04_RS16190	3541662..3542264	-	603	WP_103941405.1	TetR/AcrR family transcriptional regulator	-
OA04_RS16195	3542382..3543305	+	924	WP_103940837.1	NADP-dependent oxidoreductase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	3535321..3562204	26883

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin HigB-like (12-105)

Antitoxin

• Cro/C1-type helix-turn-helix domain (34-86)

Sequences

Toxin

Protein

• Length: 115 a.a.
• Molecular weight: 12418.13 Da
• Isoelectric Point: 9.7825

>T88808 WP_103940843.1 NZ_CP024842:3538175-3538519 [Pectobacterium versatile]
MKSLYWVGSSKKDLQSLPADVQDVFGYALHLAQTGGKHTQAKPLKGFGGAGVLEVVEDYIGDTYRAVYTVKFGEAVYVLH
AFQKKSSSGIATQKPDMNTIRERLKTAENHAKGA

Nucleotide

• Length: 345 bp

>T88808 NZ_CP024842:3538175-3538519 [Pectobacterium versatile]
ATGAAATCACTCTACTGGGTTGGCAGTAGCAAAAAGGATCTCCAGTCGCTACCTGCAGATGTGCAGGATGTGTTCGGTTA
TGCACTTCATCTGGCTCAAACTGGTGGTAAACACACTCAAGCTAAGCCGCTGAAAGGTTTTGGTGGTGCGGGCGTATTAG
AAGTCGTTGAGGATTATATCGGCGATACTTATCGCGCAGTCTACACCGTCAAATTTGGAGAAGCAGTATACGTTCTACAT
GCTTTTCAGAAAAAATCGTCATCTGGAATTGCAACACAGAAACCCGATATGAACACCATTCGTGAACGCCTTAAAACCGC
AGAGAATCATGCAAAAGGAGCATAA

Antitoxin

Protein

• Length: 106 a.a.
• Molecular weight: 11372.41 Da
• Isoelectric Point: 10.8066

>AT88808 WP_103940841.1 NZ_CP024842:3538521-3538838 [Pectobacterium versatile]
MSQDIEVSSGNVYADLGNLHAEGMLVKAQLATLISSIIKSRRLTQAEAAKLLGIPQPKLSNLLRGQFRGISETKMLECLT
KLGRDIQIVVGKPRRTPGSVKVVFA

Nucleotide

• Length: 318 bp

>AT88808 NZ_CP024842:3538521-3538838 [Pectobacterium versatile]
ATGAGCCAGGATATTGAAGTCAGCAGCGGTAATGTATACGCCGACCTTGGTAACTTGCATGCTGAAGGTATGTTGGTTAA
AGCGCAGCTTGCTACCCTGATTAGCTCAATCATCAAAAGCCGCCGTCTCACACAGGCAGAAGCAGCGAAGCTATTGGGCA
TACCCCAACCAAAGCTATCCAACCTATTGCGTGGCCAATTCAGGGGAATCAGCGAAACCAAAATGCTGGAATGCCTTACG
AAGTTGGGACGCGATATACAGATCGTTGTAGGGAAGCCGCGCCGCACGCCGGGCAGCGTTAAAGTCGTGTTTGCATGA