Detailed information of TA system TA088805

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-RelB
• Location: 2901163..2901689
• Replicon: chromosome
• Accession: NZ_CP024842
• Organism: Pectobacterium versatile strain 3-2

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: OA04_RS13195
• Protein ID: WP_107333022.1
• Coordinates: 2901402..2901689 (+)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: -
• Locus tag: OA04_RS13190
• Protein ID: WP_107333021.1
• Coordinates: 2901163..2901402 (+)
• Length: 80 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OA04_RS13170	2896586..2897809	+	1224	WP_107333019.1	hypothetical protein	-
OA04_RS13175	2897816..2898160	-	345	WP_107333020.1	antitermination protein	-
OA04_RS13180	2898500..2899942	+	1443	WP_043135453.1	IS1182 family transposase	-
OA04_RS13185	2900239..2900856	+	618	WP_019083811.1	LysE family transporter	-
OA04_RS13190	2901163..2901402	+	240	WP_107333021.1	type II toxin-antitoxin system RelB/DinJ family antitoxin	Antitoxin
OA04_RS13195	2901402..2901689	+	288	WP_107333022.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
OA04_RS13200	2901707..2902066	+	360	WP_107333023.1	hypothetical protein	-
OA04_RS13205	2902265..2902624	-	360	WP_039475580.1	ankyrin repeat domain-containing protein	-
OA04_RS13210	2903009..2903473	-	465	WP_107333717.1	GyrI-like domain-containing protein	-
OA04_RS13215	2903621..2904343	-	723	WP_107333024.1	alpha/beta fold hydrolase	-
OA04_RS13220	2904587..2904916	-	330	WP_010294841.1	DHCW motif cupin fold protein	-
OA04_RS13225	2904983..2905519	-	537	WP_107333025.1	rhodanese family protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	inside	Genomic island	-	-	2889801..2903473	13672

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (5-84)

Antitoxin

• RelB antitoxin/Antitoxin DinJ (3-79)

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11302.14 Da
• Isoelectric Point: 10.1960

>T88805 WP_107333022.1 NZ_CP024842:2901402-2901689 [Pectobacterium versatile]
MSYFLDFDERALKEWRKLGETVRNQFKKKLTDILDAPRIEANKLRGMPDCYKIKLRSAGYRLVYQVQDEKVVVFVVSVGK
RERSEAYDDAIKRLR

Nucleotide

• Length: 288 bp

>T88805 NZ_CP024842:2901402-2901689 [Pectobacterium versatile]
ATGTCGTACTTTCTGGATTTTGACGAACGCGCACTAAAGGAATGGCGCAAACTGGGCGAGACTGTTCGTAATCAATTCAA
AAAGAAACTGACTGATATTCTGGATGCCCCACGTATTGAAGCCAACAAACTGCGTGGGATGCCAGATTGCTACAAAATAA
AACTACGCTCTGCTGGCTACCGATTGGTCTACCAGGTTCAGGATGAAAAGGTGGTAGTTTTTGTTGTGTCAGTTGGCAAA
CGTGAGCGATCCGAAGCATATGATGACGCGATAAAACGATTACGCTAA

Antitoxin

Protein

• Length: 80 a.a.
• Molecular weight: 9037.34 Da
• Isoelectric Point: 4.5112

>AT88805 WP_107333021.1 NZ_CP024842:2901163-2901402 [Pectobacterium versatile]
MGSINLRIDDDLKTRSYAALEKLGVTPSEALRLTLEYIAENERLPFKQALLSDEDAELVEIVRERLRNPKPVRVTLDDL

Nucleotide

• Length: 240 bp

>AT88805 NZ_CP024842:2901163-2901402 [Pectobacterium versatile]
ATGGGCAGCATTAATCTCCGTATCGATGATGATCTTAAAACACGCTCCTACGCCGCACTCGAAAAATTGGGAGTTACGCC
TTCAGAAGCATTGCGTCTTACATTGGAATACATTGCTGAAAATGAACGACTTCCTTTTAAACAGGCATTACTTAGTGATG
AAGATGCTGAGCTGGTTGAAATTGTTCGTGAACGTCTTCGCAACCCCAAGCCAGTACGCGTGACGTTGGATGATCTTTAA