88803

Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type VII Classification (family/domain) HepT-MntA/HepT(toxin)
Location 1629219..1630018 Replicon chromosome
Accession NZ_CP024842
Organism Pectobacterium versatile strain 3-2

Toxin (Protein)


Gene name hepT Uniprot ID A0A094S5N0
Locus tag OA04_RS07385 Protein ID WP_044203394.1
Coordinates 1629219..1629638 (-) Length 140 a.a.

Antitoxin (Protein)


Gene name mntA Uniprot ID A0A094SX92
Locus tag OA04_RS07390 Protein ID WP_039473810.1
Coordinates 1629635..1630018 (-) Length 128 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OA04_RS07365 1624330..1624971 + 642 WP_010281304.1 uridine kinase -
OA04_RS07370 1625078..1625659 + 582 WP_039482649.1 dCTP deaminase -
OA04_RS07375 1625723..1627558 + 1836 WP_103860269.1 outer membrane assembly protein AsmA -
OA04_RS07380 1627823..1629175 + 1353 WP_107332578.1 anaerobic C4-dicarboxylate transporter DcuC -
OA04_RS07385 1629219..1629638 - 420 WP_044203394.1 DUF86 domain-containing protein Toxin
OA04_RS07390 1629635..1630018 - 384 WP_039473810.1 nucleotidyltransferase domain-containing protein Antitoxin
OA04_RS07395 1630131..1631717 - 1587 WP_107332579.1 TerC family protein -
OA04_RS07400 1632447..1633544 + 1098 WP_107332580.1 UDP-N-acetylglucosamine--undecaprenyl-phosphate N-acetylglucosaminephosphotransferase -
OA04_RS07405 1633662..1634798 + 1137 WP_039473807.1 polysaccharide export protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Ribonuclease HepT-like

(13-130)

Antitoxin

Polymerase beta, nucleotidyltransferase

(4-93)


Sequences

Toxin        


Download         Length: 140 a.a.        Molecular weight: 16057.39 Da        Isoelectric Point: 7.3228

>T88803 WP_044203394.1 NZ_CP024842:c1629638-1629219 [Pectobacterium versatile]
MTDILLNKSSTIQRCLRRIREEFDTEEGFRQNFTKQDSVILNIQRACEAAIDIANYLIRIKQLGIPQSSRDSFALLAANQ
IITVDLSDNLQKMVGLRNIAVHDYQALNLDIVIHVISHRLSDFERFIKQIARYSDSQHL

Download         Length: 420 bp

>T88803 NZ_CP024842:c1629638-1629219 [Pectobacterium versatile]
ATGACAGATATCTTGCTCAACAAAAGCAGCACCATACAGAGATGCCTACGTCGTATTCGTGAGGAATTCGATACTGAGGA
AGGGTTTCGTCAAAACTTCACCAAGCAAGATTCCGTCATACTTAACATACAGCGTGCCTGTGAAGCCGCTATTGATATCG
CTAATTATCTTATCCGTATCAAGCAGTTAGGTATACCACAAAGTAGCCGCGATAGCTTCGCGCTTCTTGCTGCAAACCAG
ATTATTACGGTTGATCTGTCTGACAATTTGCAAAAAATGGTGGGATTAAGAAATATTGCCGTGCATGACTACCAGGCGCT
CAATCTGGATATTGTCATCCACGTCATTTCTCATCGTTTAAGCGACTTTGAACGTTTTATCAAACAAATAGCCCGGTACA
GCGACAGCCAGCACCTTTAG

Antitoxin


Download         Length: 128 a.a.        Molecular weight: 14372.57 Da        Isoelectric Point: 4.7463

>AT88803 WP_039473810.1 NZ_CP024842:c1630018-1629635 [Pectobacterium versatile]
MFDKIVLTLKKQMPDIKIIYLFGSQATGNARADSDIDIAIMATRALDPVERWELSNQLAKEVGHDVDLIDLLQASTVLKM
EIVRNGKLLYDAETAAGEFEMTTLSMYQHLQKERADIIRSFNQDLKA

Download         Length: 384 bp

>AT88803 NZ_CP024842:c1630018-1629635 [Pectobacterium versatile]
ATGTTCGATAAGATCGTTTTGACACTGAAAAAACAGATGCCCGACATCAAAATTATTTATCTCTTTGGTTCCCAGGCTAC
AGGCAATGCCAGAGCGGACAGCGACATTGATATCGCCATCATGGCTACAAGAGCACTGGATCCCGTTGAACGCTGGGAGC
TATCTAATCAATTAGCAAAAGAAGTGGGTCATGACGTCGATCTTATCGATTTATTGCAGGCTTCAACGGTATTAAAAATG
GAGATCGTTCGTAACGGCAAGCTGCTTTATGATGCGGAAACAGCAGCGGGGGAATTTGAAATGACAACACTTTCAATGTA
CCAGCATCTGCAAAAAGAGCGTGCGGATATCATTCGTAGCTTTAATCAGGATCTAAAAGCATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A094S5N0

Antitoxin

Source ID Structure
AlphaFold DB A0A094SX92

References