Detailed information of TA system TA088801

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): cptAB/Cpta(toxin)
• Location: 789407..790067
• Replicon: chromosome
• Accession: NZ_CP024842
• Organism: Pectobacterium versatile strain 3-2

Toxin (Protein)

• Gene name: cptA
• Uniprot ID: -
• Locus tag: OA04_RS03620
• Protein ID: WP_103861404.1
• Coordinates: 789654..790067 (+)
• Length: 138 a.a.

Antitoxin (Protein)

• Gene name: cptB
• Uniprot ID: A0A1V2R9A9
• Locus tag: OA04_RS03615
• Protein ID: WP_039355397.1
• Coordinates: 789407..789673 (+)
• Length: 89 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OA04_RS03595	785385..786389	-	1005	WP_107332302.1	substrate-binding domain-containing protein	-
OA04_RS03600	786444..787052	-	609	WP_095701613.1	HD domain-containing protein	-
OA04_RS03605	787331..787978	+	648	WP_103183036.1	hemolysin III family protein	-
OA04_RS03610	788170..789171	-	1002	WP_107332303.1	tRNA-modifying protein YgfZ	-
OA04_RS03615	789407..789673	+	267	WP_039355397.1	FAD assembly factor SdhE	Antitoxin
OA04_RS03620	789654..790067	+	414	WP_103861404.1	protein YgfX	Toxin
OA04_RS03625	790136..791071	+	936	WP_107332304.1	23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF	-
OA04_RS03630	791137..791460	-	324	WP_010301820.1	hypothetical protein	-
OA04_RS03635	791489..792007	-	519	WP_103971790.1	flavodoxin FldB	-
OA04_RS03640	792347..792733	-	387	WP_107332305.1	acyl-CoA thioesterase	-
OA04_RS03645	792958..794286	-	1329	WP_103861399.1	MHS family MFS transporter	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Inner membrane protein YgfX (2-132)

Antitoxin

• Flavinator of succinate dehydrogenase (8-79)

Sequences

Toxin

Protein

• Length: 138 a.a.
• Molecular weight: 16359.31 Da
• Isoelectric Point: 10.7911

>T88801 WP_103861404.1 NZ_CP024842:789654-790067 [Pectobacterium versatile]
VAQWRCDLRVSWRMQLLSLVVHGLLVLFILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQ
EWQIVKRPWLLKNGVLLSLQAVNAKDKQQLWLASDSMGDDEWRHLRQLLLQQKHWAR

Nucleotide

• Length: 414 bp

>T88801 NZ_CP024842:789654-790067 [Pectobacterium versatile]
GTGGCCCAGTGGCGATGTGACCTTCGCGTTTCCTGGCGCATGCAGCTGCTGTCATTGGTGGTGCATGGCCTCTTAGTATT
ATTCATTCTGCTGGCACCGTGGCCGGACGGCTATGCGTGGCTATGGCTATGCCTGGTCACGATGGTGATGTTCGGTTTTA
TCCGTAGCCAAAGGAATATTAAATCCCGACAGGGGGAAATCGTTCTGCTCAGCGAAACGACCCTGAACTGGCGGCAGCAG
GAATGGCAAATCGTTAAGCGGCCGTGGCTGCTGAAGAATGGCGTGTTGCTGTCATTACAAGCGGTTAACGCTAAAGACAA
GCAACAGCTGTGGCTGGCATCGGACAGCATGGGCGATGATGAATGGCGTCACTTGCGTCAGCTTCTTTTGCAGCAGAAAC
ACTGGGCAAGATAG

Antitoxin

Protein

• Length: 89 a.a.
• Molecular weight: 10506.99 Da
• Isoelectric Point: 6.2223

>AT88801 WP_039355397.1 NZ_CP024842:789407-789673 [Pectobacterium versatile]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPKDGELKRMISLIQTRN
KDRGPVAM

Nucleotide

• Length: 267 bp

>AT88801 NZ_CP024842:789407-789673 [Pectobacterium versatile]
ATGGAAATCGATAATAAATCACGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAATTGGATATCGCGATCATGCCGTT
TTTTGAGCATGACTATGACACACTTAATGACACTGATAAGCGTACGTTTGTACGTTTGTTACAAAGCGACGATCCCGATT
TATTCAACTGGCTGATGAACCACGGTGAACCGAAGGACGGAGAGCTGAAACGCATGATTTCCCTTATTCAGACGCGAAAT
AAAGACCGTGGCCCAGTGGCGATGTGA

Structures

Antitoxin

• AlphaFold DB: A0A1V2R9A9