Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 506878..507403 Replicon chromosome
Accession NZ_CP024842
Organism Pectobacterium versatile strain 3-2

Toxin (Protein)


Gene name relE Uniprot ID A0A1D7Z1B4
Locus tag OA04_RS02335 Protein ID WP_005973612.1
Coordinates 507119..507403 (+) Length 95 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID C6D956
Locus tag OA04_RS02330 Protein ID WP_005973616.1
Coordinates 506878..507129 (+) Length 84 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OA04_RS02285 501882..502106 + 225 WP_005973635.1 hypothetical protein -
OA04_RS02290 502115..502504 + 390 Protein_430 ash family protein -
OA04_RS02295 502468..502665 + 198 WP_005973632.1 host cell division inhibitor Icd-like protein -
OA04_RS02300 502658..502852 + 195 WP_005973630.1 hypothetical protein -
OA04_RS02305 502849..503115 + 267 WP_005973627.1 hypothetical protein -
OA04_RS02310 503112..503453 + 342 WP_005973624.1 DUF5375 family protein -
OA04_RS02315 503464..505791 + 2328 WP_107332225.1 toprim domain-containing protein -
OA04_RS02320 505845..506324 - 480 WP_005973620.1 GNAT family N-acetyltransferase -
OA04_RS02325 506315..506587 - 273 WP_005973618.1 DUF1778 domain-containing protein -
OA04_RS02330 506878..507129 + 252 WP_005973616.1 prevent-host-death protein Antitoxin
OA04_RS02335 507119..507403 + 285 WP_005973612.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
OA04_RS02340 507840..509045 - 1206 WP_102119601.1 ISL3 family transposase -
OA04_RS02345 509421..509849 + 429 WP_107332226.1 GNAT family N-acetyltransferase -
OA04_RS02350 509940..511061 + 1122 WP_107332227.1 cupin domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 495499..509045 13546


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 95 a.a.        Molecular weight: 11010.96 Da        Isoelectric Point: 10.1716

>T88799 WP_005973612.1 NZ_CP024842:507119-507403 [Pectobacterium versatile]
MSYKLEFEEHALKEFKKLGAPVREQFTKKLKEVLQNPHVPANRLHGMADCYKIKLRSAGYRLVYQVLEHEIVVLVLAVGK
RERSEVYKTAKDRL

Download         Length: 285 bp

>T88799 NZ_CP024842:507119-507403 [Pectobacterium versatile]
ATGAGTTATAAGCTGGAGTTTGAAGAGCACGCGCTGAAAGAATTTAAGAAGCTGGGTGCGCCCGTGCGGGAGCAGTTCAC
CAAAAAGTTGAAAGAGGTTTTACAAAATCCCCACGTTCCCGCCAACCGACTTCATGGAATGGCTGACTGCTACAAAATCA
AACTTCGTTCCGCTGGCTATCGGTTAGTGTATCAAGTACTTGAGCATGAGATCGTGGTGCTGGTTTTAGCTGTGGGCAAA
CGGGAACGCTCAGAAGTTTATAAAACAGCGAAAGACCGACTATAA

Antitoxin


Download         Length: 84 a.a.        Molecular weight: 9079.35 Da        Isoelectric Point: 5.0807

>AT88799 WP_005973616.1 NZ_CP024842:506878-507129 [Pectobacterium versatile]
MSVQPILANAAVSISDFKKSPNAALKEANGEPVAVLTNGRISGYYVSPETWEALADYQEDIELAKIARSRMKGKRVKVDL
DEL

Download         Length: 252 bp

>AT88799 NZ_CP024842:506878-507129 [Pectobacterium versatile]
ATGTCCGTACAACCTATCCTTGCGAATGCTGCCGTAAGTATCAGCGACTTTAAAAAATCGCCCAATGCCGCGCTTAAAGA
AGCTAACGGCGAGCCTGTAGCCGTGCTCACCAATGGCCGTATCTCTGGCTATTATGTTTCCCCGGAAACATGGGAAGCGC
TGGCCGATTATCAGGAAGATATCGAACTTGCCAAAATCGCCCGTTCCCGGATGAAGGGGAAACGTGTGAAGGTCGATCTG
GATGAGTTATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D7Z1B4

Antitoxin

Source ID Structure
AlphaFold DB A0A0G4JQP6

References