Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacT-ataR/DUF1778(antitoxin)
Location 505845..506587 Replicon chromosome
Accession NZ_CP024842
Organism Pectobacterium versatile strain 3-2

Toxin (Protein)


Gene name tacT Uniprot ID A0A1D7Z1H7
Locus tag OA04_RS02320 Protein ID WP_005973620.1
Coordinates 505845..506324 (-) Length 160 a.a.

Antitoxin (Protein)


Gene name ataR Uniprot ID A0A1D7Z1H8
Locus tag OA04_RS02325 Protein ID WP_005973618.1
Coordinates 506315..506587 (-) Length 91 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
OA04_RS02280 501625..501885 + 261 WP_005973638.1 AlpA family transcriptional regulator -
OA04_RS02285 501882..502106 + 225 WP_005973635.1 hypothetical protein -
OA04_RS02290 502115..502504 + 390 Protein_430 ash family protein -
OA04_RS02295 502468..502665 + 198 WP_005973632.1 host cell division inhibitor Icd-like protein -
OA04_RS02300 502658..502852 + 195 WP_005973630.1 hypothetical protein -
OA04_RS02305 502849..503115 + 267 WP_005973627.1 hypothetical protein -
OA04_RS02310 503112..503453 + 342 WP_005973624.1 DUF5375 family protein -
OA04_RS02315 503464..505791 + 2328 WP_107332225.1 toprim domain-containing protein -
OA04_RS02320 505845..506324 - 480 WP_005973620.1 GNAT family N-acetyltransferase Toxin
OA04_RS02325 506315..506587 - 273 WP_005973618.1 DUF1778 domain-containing protein Antitoxin
OA04_RS02330 506878..507129 + 252 WP_005973616.1 prevent-host-death protein -
OA04_RS02335 507119..507403 + 285 WP_005973612.1 type II toxin-antitoxin system RelE/ParE family toxin -
OA04_RS02340 507840..509045 - 1206 WP_102119601.1 ISL3 family transposase -
OA04_RS02345 509421..509849 + 429 WP_107332226.1 GNAT family N-acetyltransferase -
OA04_RS02350 509940..511061 + 1122 WP_107332227.1 cupin domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 495499..509045 13546


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(28-147)

Antitoxin

Vibrio phage ICP1, Orf50

(10-85)


Sequences

Toxin        


Download         Length: 160 a.a.        Molecular weight: 17504.13 Da        Isoelectric Point: 8.9715

>T88798 WP_005973620.1 NZ_CP024842:c506324-505845 [Pectobacterium versatile]
VGITAPELLLPQHAVVDFRSSEPSLDDWLKRKALKNQTMGASRTFVVCESSANQVIGFYALATGSVQRQSVSGALRRNMP
DPLPVLVLGRLAVDERYHRQGIGAGLLKDAILRSRQVAEQVGTKALLVHALSEDAKDFYLHWGFTSSEIQPNTLLLPLW

Download         Length: 480 bp

>T88798 NZ_CP024842:c506324-505845 [Pectobacterium versatile]
GTGGGAATAACGGCACCTGAATTATTATTACCTCAGCATGCCGTGGTTGATTTCCGAAGTTCAGAACCGTCACTGGATGA
CTGGCTGAAGCGTAAGGCGCTCAAGAATCAAACCATGGGCGCATCACGCACTTTTGTCGTGTGTGAATCGAGTGCTAATC
AGGTTATTGGCTTTTACGCGCTGGCAACCGGCAGCGTACAGCGCCAATCCGTATCGGGTGCGTTACGACGCAATATGCCT
GATCCGCTGCCCGTATTAGTCTTGGGTCGTCTGGCGGTAGATGAACGTTATCACCGTCAGGGGATTGGCGCGGGACTATT
AAAAGATGCGATCTTGCGTTCCCGGCAGGTTGCTGAACAGGTGGGAACGAAAGCGTTATTAGTTCATGCGCTGTCTGAGG
ACGCAAAAGATTTTTATCTGCATTGGGGCTTTACGTCCTCGGAAATCCAGCCTAACACATTGCTTCTACCACTCTGGTAA

Antitoxin


Download         Length: 91 a.a.        Molecular weight: 10306.80 Da        Isoelectric Point: 4.7174

>AT88798 WP_005973618.1 NZ_CP024842:c506587-506315 [Pectobacterium versatile]
MRTEAKEAPINIRAKSSQRELIDVAAKMLSKSRTDFILEAACREAEEVLLDQRLFLVDESQFDAFITALEKPVATNERLQ
ALLDRKSPWE

Download         Length: 273 bp

>AT88798 NZ_CP024842:c506587-506315 [Pectobacterium versatile]
ATGAGAACAGAGGCAAAAGAGGCACCGATCAACATTAGGGCGAAATCATCACAACGGGAACTGATAGACGTTGCCGCGAA
AATGCTTTCAAAGTCACGTACTGATTTTATCCTTGAGGCTGCATGTCGTGAGGCGGAAGAGGTGCTATTGGATCAACGCC
TGTTTCTGGTTGATGAATCACAATTTGATGCCTTTATTACCGCGTTAGAAAAACCTGTCGCCACCAATGAGCGGTTACAG
GCGTTATTAGACAGGAAATCACCGTGGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D7Z1H7

Antitoxin

Source ID Structure
AlphaFold DB A0A1D7Z1H8

References