Detailed information of TA system TA088793

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): relBE/ParE-YafN
• Location: 88017..88552
• Replicon: chromosome
• Accession: NZ_CP024842
• Organism: Pectobacterium versatile strain 3-2

Toxin (Protein)

• Gene name: relE
• Uniprot ID: -
• Locus tag: OA04_RS00360
• Protein ID: WP_107332095.1
• Coordinates: 88017..88304 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: relB
• Uniprot ID: Q6DB37
• Locus tag: OA04_RS00365
• Protein ID: WP_010281712.1
• Coordinates: 88301..88552 (-)
• Length: 84 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
OA04_RS00350	83600..84952	+	1353	WP_103862838.1	glutathione-disulfide reductase	-
OA04_RS00355	85096..87879	-	2784	WP_107332094.1	AAA family ATPase	-
OA04_RS00360	88017..88304	-	288	WP_107332095.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
OA04_RS00365	88301..88552	-	252	WP_010281712.1	type II toxin-antitoxin system Phd/YefM family antitoxin	Antitoxin
OA04_RS00370	88809..89714	+	906	WP_107332096.1	siderophore-interacting protein	-
OA04_RS00375	89749..90504	-	756	WP_107332097.1	thiol:disulfide interchange protein DsbG	-
OA04_RS00380	90783..91406	+	624	WP_107332098.1	LysE family translocator	-
OA04_RS00385	91467..92507	-	1041	WP_107332099.1	HipA domain-containing protein	-
OA04_RS00390	92504..92818	-	315	WP_107332100.1	HipA N-terminal domain-containing protein	-
OA04_RS00395	92803..93129	-	327	WP_103862833.1	helix-turn-helix domain-containing protein	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (4-82)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11070.17 Da
• Isoelectric Point: 10.3856

>T88793 WP_107332095.1 NZ_CP024842:c88304-88017 [Pectobacterium versatile]
MSYRVKFREDALKEWLKLDKAIQQQFAKKLKKCCENPHIPAATLRGMKDCYKIKLRASGFRLVYEVIDDILVIAVVAVGK
RERSGVYHLASERMR

Nucleotide

• Length: 288 bp

>T88793 NZ_CP024842:c88304-88017 [Pectobacterium versatile]
ATGAGTTATCGCGTCAAATTCAGGGAAGATGCGCTAAAAGAATGGCTAAAACTCGATAAAGCTATCCAACAGCAATTCGC
CAAAAAACTAAAAAAATGCTGCGAAAATCCCCATATTCCTGCGGCAACGTTACGAGGGATGAAGGACTGCTACAAAATCA
AGCTCCGAGCGTCAGGCTTTCGTTTGGTTTACGAAGTCATTGACGACATATTGGTTATCGCCGTGGTGGCGGTAGGCAAA
CGTGAGCGTAGTGGCGTTTATCATCTGGCGAGTGAACGAATGAGGTAG

Antitoxin

Protein

• Length: 84 a.a.
• Molecular weight: 9117.47 Da
• Isoelectric Point: 4.0637

>AT88793 WP_010281712.1 NZ_CP024842:c88552-88301 [Pectobacterium versatile]
MPNIILSDTSASVSELKKNPMATVNAGDGLPVAILNRNQPAFYCIPADLYEKMLDALDDQELVKLIGERKNQPLVDVDLD
SFL

Nucleotide

• Length: 252 bp

>AT88793 NZ_CP024842:c88552-88301 [Pectobacterium versatile]
ATGCCGAATATTATATTAAGCGATACCAGTGCTAGCGTCAGTGAACTGAAAAAGAACCCAATGGCGACGGTCAATGCTGG
AGATGGCCTACCTGTCGCTATCTTGAACCGCAACCAGCCTGCGTTTTATTGCATTCCTGCGGATCTCTACGAAAAAATGC
TGGATGCGCTGGACGACCAAGAATTGGTTAAGCTGATCGGTGAACGTAAAAACCAGCCGCTGGTTGACGTGGATTTGGAT
AGTTTCCTATGA

Structures

Antitoxin

• AlphaFold DB: A0A0M2EZP0