Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4233149..4233294 Replicon chromosome
Accession NZ_CP024838
Organism Klebsiella pneumoniae strain CRKP-1215

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4233185..4233287 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4233149..4233294 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CU074_RS21115 4228279..4230339 + 2061 WP_004151449.1 oligopeptidase B -
CU074_RS21120 4230343..4231002 - 660 WP_002911407.1 exodeoxyribonuclease X -
CU074_RS21125 4231081..4231311 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CU074_RS21130 4231424..4231798 + 375 WP_039819395.1 CopC domain-containing protein YobA -
CU074_RS21135 4231802..4232671 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
CU074_RS21140 4232688..4233026 + 339 WP_002911404.1 YebY family protein -
- 4233149..4233294 - 146 - - Antitoxin
- 4233185..4233287 + 103 - - Toxin
CU074_RS29325 4233663..4233806 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
CU074_RS21150 4233911..4234879 - 969 WP_014907334.1 VirK/YbjX family protein -
CU074_RS21155 4235036..4235689 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
CU074_RS21160 4235686..4235877 - 192 WP_002911395.1 YebW family protein -
CU074_RS21165 4235975..4236214 - 240 WP_002911393.1 YebV family protein -
CU074_RS21170 4236330..4237763 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T88779 NZ_CP024838:4233185-4233287 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT88779 NZ_CP024838:c4233294-4233149 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References