Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 1575310..1575455 Replicon chromosome
Accession NZ_CP024834
Organism Klebsiella pneumoniae strain CRKP-2297

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 1575346..1575448 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 1575310..1575455 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CU075_RS07900 1570440..1572500 + 2061 WP_004151449.1 oligopeptidase B -
CU075_RS07905 1572504..1573163 - 660 WP_002911407.1 exodeoxyribonuclease X -
CU075_RS07910 1573242..1573472 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CU075_RS07915 1573585..1573959 + 375 WP_039819395.1 CopC domain-containing protein YobA -
CU075_RS07920 1573963..1574832 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
CU075_RS07925 1574849..1575187 + 339 WP_002911404.1 YebY family protein -
- 1575310..1575455 - 146 - - Antitoxin
- 1575346..1575448 + 103 - - Toxin
CU075_RS29115 1575824..1575967 - 144 WP_038431282.1 Ecr family regulatory small membrane protein -
CU075_RS07935 1576072..1577040 - 969 WP_014907334.1 VirK/YbjX family protein -
CU075_RS07940 1577197..1577850 + 654 WP_024622748.1 protein-serine/threonine phosphatase -
CU075_RS07945 1577847..1578038 - 192 WP_002911395.1 YebW family protein -
CU075_RS07950 1578136..1578375 - 240 WP_002911393.1 YebV family protein -
CU075_RS07955 1578491..1579924 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T88750 NZ_CP024834:1575346-1575448 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT88750 NZ_CP024834:c1575455-1575310 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References