Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2024013..2024284 Replicon chromosome
Accession NZ_CP024801
Organism Escherichia coli strain AMA1167

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2024143..2024246 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2024013..2024284 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CUC42_RS10310 2020568..2021230 - 663 WP_000944256.1 exodeoxyribonuclease X -
CUC42_RS10315 2021254..2021910 - 657 WP_000011658.1 carbon-nitrogen hydrolase family protein -
CUC42_RS10320 2022012..2022242 - 231 WP_000916763.1 DNA polymerase III subunit theta -
CUC42_RS10325 2022381..2022755 + 375 WP_000204699.1 CopC domain-containing protein YobA -
CUC42_RS10330 2022759..2023631 + 873 WP_000879280.1 copper homeostasis membrane protein CopD -
CUC42_RS10335 2023644..2023985 + 342 WP_000976492.1 YebY family protein -
- 2024013..2024284 - 272 - - Antitoxin
- 2024143..2024246 + 104 - - Toxin
CUC42_RS10340 2024381..2025037 + 657 WP_000812724.1 protein-serine/threonine phosphatase -
CUC42_RS10345 2025038..2025229 - 192 WP_001296140.1 YebW family protein -
CUC42_RS10350 2025334..2025570 - 237 WP_001295499.1 DUF1480 family protein -
CUC42_RS10355 2025688..2027127 - 1440 WP_000057023.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 1981100..2027133 46033


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T88533 NZ_CP024801:2024143-2024246 [Escherichia coli]
GGCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 272 bp

>AT88533 NZ_CP024801:c2024284-2024013 [Escherichia coli]
AAAGTCAGCGAAGGAAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCCCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTGAAATGTTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTTTAT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References