Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 6716952..6717558 Replicon chromosome
Accession NZ_CP024785
Organism Nostoc flagelliforme CCNUN1

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag COO91_RS30950 Protein ID WP_100901646.1
Coordinates 6717184..6717558 (+) Length 125 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag COO91_RS30945 Protein ID WP_100901645.1
Coordinates 6716952..6717191 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
COO91_RS30925 6713005..6713778 + 774 WP_100901642.1 red chlorophyll catabolite reductase -
COO91_RS30930 6713811..6714866 + 1056 WP_100901643.1 nitrilase -
COO91_RS30935 6715011..6716429 + 1419 WP_100901644.1 aldehyde dehydrogenase family protein -
COO91_RS49960 6716426..6716746 + 321 WP_167407668.1 hypothetical protein -
COO91_RS30945 6716952..6717191 + 240 WP_100901645.1 hypothetical protein Antitoxin
COO91_RS30950 6717184..6717558 + 375 WP_100901646.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
COO91_RS52350 6717617..6717823 + 207 Protein_6086 hypothetical protein -
COO91_RS49965 6717813..6717998 + 186 WP_157816680.1 hypothetical protein -
COO91_RS30965 6718367..6718813 + 447 WP_100901647.1 DUF3598 family protein -
COO91_RS30970 6718934..6720322 + 1389 WP_100901648.1 histidine--tRNA ligase -
COO91_RS30975 6720563..6721783 + 1221 WP_100897431.1 ISL3 family transposase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 6720563..6721783 1220


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin HigB-2

(23-108)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 125 a.a.        Molecular weight: 14019.03 Da        Isoelectric Point: 6.3886

>T88517 WP_100901646.1 NZ_CP024785:6717184-6717558 [Nostoc flagelliforme CCNUN1]
MAEQPFIQVEASPTFNQNLRALAKKYRSIRNDIQPVIEQLEQGELPGDKIPGVGYAVFKLRVRNSDIQKGKSGGYRLIYY
VKTATGIILLTIYAKSEQVDIAADDIQSIITEYEQRAIKDKEDI

Download         Length: 375 bp

>T88517 NZ_CP024785:6717184-6717558 [Nostoc flagelliforme CCNUN1]
ATGGCTGAACAGCCTTTCATTCAAGTTGAAGCTTCGCCAACGTTCAACCAAAATTTACGCGCTCTTGCCAAGAAGTATCG
CAGTATTCGGAATGATATACAACCCGTCATCGAACAACTTGAGCAGGGAGAGTTGCCAGGAGATAAAATACCTGGGGTTG
GTTATGCGGTCTTCAAGTTAAGAGTCCGAAATAGCGACATTCAAAAAGGTAAAAGCGGTGGCTATCGTCTGATTTACTAT
GTCAAGACAGCAACGGGAATTATTTTGCTGACTATTTATGCAAAATCTGAACAAGTCGATATTGCCGCAGATGACATTCA
GAGCATCATTACAGAATATGAGCAACGCGCGATCAAAGATAAAGAGGATATCTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8894.10 Da        Isoelectric Point: 3.9417

>AT88517 WP_100901645.1 NZ_CP024785:6716952-6717191 [Nostoc flagelliforme CCNUN1]
MKAVKVMATINEQGQITLDYPLITDKNSRVEIIILIPEEEVLDDQSQAEVLADFRQAWHEAMTGQTIPVAQLWEGLENG

Download         Length: 240 bp

>AT88517 NZ_CP024785:6716952-6717191 [Nostoc flagelliforme CCNUN1]
ATGAAAGCAGTTAAAGTCATGGCAACGATTAATGAGCAAGGGCAAATAACTTTAGATTACCCTCTCATAACGGATAAAAA
TAGCCGTGTAGAAATTATTATTTTAATTCCAGAAGAGGAAGTTCTAGATGATCAATCTCAAGCAGAAGTCTTAGCAGATT
TCCGGCAAGCTTGGCACGAAGCCATGACTGGGCAAACTATCCCGGTGGCTCAACTTTGGGAAGGGCTTGAAAATGGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References