Detailed information of TA system TA088506

Bioinformatically predicted

Overview

TA module

• Type: II
• Classification (family/domain): stbDE/ParE-DnaT
• Location: 2911632..2912163
• Replicon: chromosome
• Accession: NZ_CP024780
• Organism: Pectobacterium brasiliense strain BZA12

Toxin (Protein)

• Gene name: stbE
• Uniprot ID: -
• Locus tag: CTV95_RS13145
• Protein ID: WP_100017717.1
• Coordinates: 2911632..2911919 (-)
• Length: 96 a.a.

Antitoxin (Protein)

• Gene name: stbD
• Uniprot ID: A0A1V2R9J2
• Locus tag: CTV95_RS13150
• Protein ID: WP_039282788.1
• Coordinates: 2911909..2912163 (-)
• Length: 85 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CTV95_RS13115	2906752..2908143	+	1392	WP_039282780.1	outer membrane channel protein TolC	-
CTV95_RS13125	2908562..2909236	+	675	WP_010280216.1	DUF1190 family protein	-
CTV95_RS13130	2909248..2910408	+	1161	WP_100017716.1	glutathionylspermidine synthase family protein	-
CTV95_RS13140	2910668..2911453	-	786	WP_039282782.1	4,5-DOPA dioxygenase extradiol	-
CTV95_RS13145	2911632..2911919	-	288	WP_100017717.1	type II toxin-antitoxin system RelE/ParE family toxin	Toxin
CTV95_RS13150	2911909..2912163	-	255	WP_039282788.1	plasmid stabilization protein	Antitoxin
CTV95_RS13155	2912442..2913758	+	1317	WP_100017718.1	IS4 family transposase	-
CTV95_RS13165	2914303..2915190	-	888	WP_100017719.1	16S rRNA (cytidine(1402)-2'-O)-methyltransferase	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)
	-	flank	IS/Tn	-	-	2912442..2913758	1316

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Toxin-antitoxin system, RelE/ParE toxin family (6-82)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 96 a.a.
• Molecular weight: 11039.98 Da
• Isoelectric Point: 10.8186

>T88506 WP_100017717.1 NZ_CP024780:c2911919-2911632 [Pectobacterium brasiliense]
MTYKLKFVPSAMKEWKKLGHPVREQFKKKLVERLENPRVPSAQLHGRKDQYKIKLRSAGYRLVYLVQDETITVMVMGVGK
REGSQIYSDTKGRSA

Nucleotide

• Length: 288 bp

>T88506 NZ_CP024780:c2911919-2911632 [Pectobacterium brasiliense]
ATGACCTATAAGTTAAAATTTGTACCTTCTGCAATGAAGGAATGGAAAAAGCTAGGGCATCCTGTCCGGGAACAGTTCAA
GAAAAAGTTGGTTGAGCGTTTGGAAAATCCTCGTGTTCCTTCAGCACAGCTTCATGGCCGTAAAGACCAGTATAAAATTA
AACTGAGGTCCGCTGGCTACAGGCTGGTGTATTTGGTCCAGGATGAGACTATTACTGTGATGGTTATGGGAGTTGGAAAG
CGCGAAGGTAGCCAGATTTATTCTGATACGAAAGGTCGCTCTGCTTAA

Antitoxin

Protein

• Length: 85 a.a.
• Molecular weight: 9208.38 Da
• Isoelectric Point: 3.7947

>AT88506 WP_039282788.1 NZ_CP024780:c2912163-2911909 [Pectobacterium brasiliense]
MAFNILTNTAASITELKRDPMGTVRAAEGETIAILNRNEPAFYCVPPAVFAYLMELAEDAELGRTVDDRMSELADAEEIS
LDDL

Nucleotide

• Length: 255 bp

>AT88506 NZ_CP024780:c2912163-2911909 [Pectobacterium brasiliense]
ATGGCTTTCAACATCCTAACTAACACAGCCGCCAGTATTACTGAGTTGAAACGTGACCCGATGGGGACGGTTCGGGCTGC
TGAAGGTGAAACTATCGCTATACTGAACCGGAATGAGCCGGCATTCTACTGTGTGCCTCCTGCCGTATTCGCTTATTTAA
TGGAACTGGCTGAAGATGCAGAGCTGGGGCGTACCGTTGATGATCGGATGTCAGAGTTAGCTGACGCGGAAGAGATTTCG
CTCGATGACCTATAA

Structures

Antitoxin

• AlphaFold DB: A0A1V2R9J2