Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) mosAT/AbiEii-AbiEi
Location 2698759..2700457 Replicon chromosome
Accession NZ_CP024780
Organism Pectobacterium brasiliense strain BZA12

Toxin (Protein)


Gene name mosT Uniprot ID -
Locus tag CTV95_RS12235 Protein ID WP_100017633.1
Coordinates 2699528..2700457 (+) Length 310 a.a.

Antitoxin (Protein)


Gene name mosA Uniprot ID -
Locus tag CTV95_RS12230 Protein ID WP_039543258.1
Coordinates 2698759..2699541 (+) Length 261 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CTV95_RS12205 2695675..2696799 - 1125 WP_038918036.1 site-specific integrase -
CTV95_RS12210 2696917..2697141 - 225 WP_039355190.1 DUF1778 domain-containing protein -
CTV95_RS12220 2697631..2697840 - 210 WP_039491410.1 helix-turn-helix domain-containing protein -
CTV95_RS12225 2697837..2698298 - 462 WP_039543259.1 hypothetical protein -
CTV95_RS22450 2698325..2698557 - 233 Protein_2362 ash family protein -
CTV95_RS12230 2698759..2699541 + 783 WP_039543258.1 type IV toxin-antitoxin system AbiEi family antitoxin domain-containing protein Antitoxin
CTV95_RS12235 2699528..2700457 + 930 WP_100017633.1 nucleotidyl transferase AbiEii/AbiGii toxin family protein Toxin
CTV95_RS12240 2700838..2701740 - 903 WP_039313377.1 LysR family transcriptional regulator -
CTV95_RS12245 2701869..2702132 + 264 WP_100017634.1 DUF2798 domain-containing protein -
CTV95_RS12250 2702213..2702998 - 786 WP_198406552.1 phosphonate metabolism protein PhnP -
CTV95_RS12255 2703037..2703606 - 570 WP_100018523.1 ribose 1,5-bisphosphokinase -
CTV95_RS12260 2703725..2703937 - 213 Protein_2369 alpha-D-ribose 1-methylphosphonate 5-triphosphate diphosphatase -
CTV95_RS12265 2703934..2704155 - 222 Protein_2370 ATP-binding cassette domain-containing protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Nucleotidyl transferase AbiEii toxin, Type IV TA system

(13-262)

Antitoxin

Transcriptional regulator, AbiEi 3 antitoxin, Type IV TA system

(95-247)


Sequences

Toxin        


Download         Length: 310 a.a.        Molecular weight: 35042.40 Da        Isoelectric Point: 6.3871

>T88504 WP_100017633.1 NZ_CP024780:2699528-2700457 [Pectobacterium brasiliense]
MDQRDIYARQVRLLMTALPHVAKESCFALKGGTAINLFMQDFPRLSVDIDLVYQTFIDRDTDLAAIDDALMRITESLNGR
PGITAIRQDNKADEKRIIVNTANAQIKIEVSPVWRGLLLPPAEIPVCEQVEMEFGFTTMNVVSLADLYGGKICAALDRQH
PRDLFDVLNMLEKPGLTRELFDGFLCYLAGHPRPIAELLAPNWDIARITTLYQQEFSGMTQQETSLESLLSVTTLLPQAL
KSHFTAQDKQFLLSYKQNTPDWSLYRYPDIQHLPAIRWKQRNLSALHAKNPAKFSAAVGKLEKVLEQHF

Download         Length: 930 bp

>T88504 NZ_CP024780:2699528-2700457 [Pectobacterium brasiliense]
ATGGATCAGCGTGATATTTATGCCCGACAGGTCAGGCTGTTAATGACCGCCCTGCCTCATGTAGCGAAAGAGTCCTGTTT
CGCGCTGAAAGGCGGCACAGCTATCAATCTGTTTATGCAGGATTTCCCTCGCCTATCAGTAGATATCGATCTGGTTTATC
AAACCTTCATAGATCGTGATACCGATCTAGCCGCTATTGACGATGCCTTGATGCGCATTACCGAATCGCTGAACGGCAGG
CCGGGGATCACCGCAATTCGACAGGATAATAAAGCCGATGAAAAGCGCATCATCGTTAACACCGCTAATGCACAGATAAA
GATTGAAGTCAGTCCGGTTTGGCGTGGATTGCTGTTGCCTCCAGCAGAAATACCGGTATGCGAGCAGGTAGAAATGGAAT
TCGGCTTTACCACCATGAATGTCGTTTCACTGGCAGATCTTTACGGCGGTAAAATCTGCGCCGCGCTCGATCGCCAGCAT
CCACGCGATCTGTTTGACGTGCTAAATATGCTGGAGAAACCGGGCCTCACACGCGAGCTCTTTGATGGCTTTCTTTGCTA
TCTGGCTGGTCATCCCCGCCCCATCGCTGAACTACTGGCTCCAAACTGGGACATTGCACGAATCACAACACTGTACCAAC
AAGAATTTTCGGGCATGACGCAACAGGAAACGTCGCTGGAATCGCTTTTGTCAGTAACGACTTTACTGCCGCAAGCATTG
AAATCCCATTTTACCGCTCAGGATAAACAGTTTTTACTGAGCTATAAGCAAAACACCCCTGACTGGTCGCTATACCGCTA
TCCTGATATTCAACATCTTCCCGCCATTCGCTGGAAACAGCGTAATTTATCAGCTTTACATGCTAAAAATCCGGCCAAAT
TTAGCGCGGCAGTAGGTAAGCTTGAGAAGGTTCTGGAACAACATTTTTAG

Antitoxin


Download         Length: 261 a.a.        Molecular weight: 29323.71 Da        Isoelectric Point: 9.7263

>AT88504 WP_039543258.1 NZ_CP024780:2698759-2699541 [Pectobacterium brasiliense]
MTNYLNWLMQNTLPGQVLLQSWLTRNGIDRKLSYVYVQNGWLRRIAHGVYCRTGREPDWVDAVYCLQTQWEKPVRVAGLT
SLALQGYSHYTEPGKPQIWLTLPAYIKLPGWFTAFKPSATFVVLYTSGLSVDVMPFTTKLRIGDRRLTGSVPELAAYEIA
SGVPTQISFEHADALFQGLNLLSPRKLQPLLSASHSVKTNRVMLYLAQRNGHPYFQYLDKSGIETGAGKRQIIPGGWLEP
DYQITVPREFKSKGIEDGSA

Download         Length: 783 bp

>AT88504 NZ_CP024780:2698759-2699541 [Pectobacterium brasiliense]
TTGACAAATTATCTAAACTGGCTGATGCAAAACACCCTGCCCGGTCAGGTATTGCTCCAGTCATGGCTTACCCGCAACGG
CATAGACCGTAAGCTCTCTTACGTCTATGTCCAAAACGGTTGGCTCAGGCGGATCGCTCACGGCGTTTACTGCCGGACGG
GTCGTGAACCAGACTGGGTGGATGCGGTTTACTGCCTGCAAACTCAATGGGAAAAACCTGTGCGGGTAGCAGGGCTGACC
AGCCTTGCGCTACAGGGCTATTCCCATTATACCGAACCGGGTAAACCTCAAATTTGGCTCACGCTCCCGGCTTATATAAA
GCTACCGGGATGGTTCACCGCCTTTAAACCATCCGCCACCTTTGTCGTGCTCTATACATCAGGCCTGTCGGTTGATGTGA
TGCCATTCACGACAAAACTGAGAATCGGCGATCGGCGGCTGACTGGCAGCGTGCCAGAACTTGCCGCATATGAAATCGCC
AGCGGCGTTCCCACACAAATATCATTTGAGCATGCAGATGCATTGTTTCAGGGGCTGAACCTTCTCAGCCCGCGTAAATT
ACAGCCGCTACTCTCAGCCAGCCATTCGGTAAAAACCAACCGGGTGATGCTCTACCTTGCCCAGCGCAATGGACATCCTT
ATTTTCAGTATCTCGATAAAAGTGGTATAGAAACAGGCGCTGGAAAGCGGCAAATTATCCCCGGCGGCTGGCTGGAACCG
GATTACCAAATCACCGTTCCCAGGGAATTTAAATCGAAAGGAATCGAAGATGGATCAGCGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References