Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type IV Classification (family/domain) cptAB/Cpta(toxin)
Location 2530533..2531193 Replicon chromosome
Accession NZ_CP024780
Organism Pectobacterium brasiliense strain BZA12

Toxin (Protein)


Gene name cptA Uniprot ID A0A837DIN4
Locus tag CTV95_RS11430 Protein ID WP_039275532.1
Coordinates 2530533..2530946 (-) Length 138 a.a.

Antitoxin (Protein)


Gene name cptB Uniprot ID A0A1D7Z1Z6
Locus tag CTV95_RS11435 Protein ID WP_005971623.1
Coordinates 2530927..2531193 (-) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CTV95_RS11405 2526331..2527659 + 1329 WP_039282120.1 MHS family MFS transporter -
CTV95_RS11410 2527864..2528250 + 387 WP_039282122.1 thioesterase family protein -
CTV95_RS11415 2528593..2529111 + 519 WP_014914178.1 flavodoxin FldB -
CTV95_RS11420 2529140..2529463 + 324 WP_014914177.1 hypothetical protein -
CTV95_RS11425 2529529..2530464 - 936 WP_010301818.1 23S rRNA (adenine(1618)-N(6))-methyltransferase RlmF -
CTV95_RS11430 2530533..2530946 - 414 WP_039275532.1 protein YgfX Toxin
CTV95_RS11435 2530927..2531193 - 267 WP_005971623.1 FAD assembly factor SdhE Antitoxin
CTV95_RS11440 2531429..2532430 + 1002 WP_100017576.1 tRNA-modifying protein YgfZ -
CTV95_RS11445 2532485..2533132 - 648 WP_100017577.1 hemolysin III family protein -
CTV95_RS11450 2533562..2534170 + 609 WP_100017578.1 HD domain-containing protein -
CTV95_RS11455 2534225..2535229 + 1005 WP_100017579.1 LacI family DNA-binding transcriptional regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Inner membrane protein YgfX

(2-132)

Antitoxin

Flavinator of succinate dehydrogenase

(8-79)


Sequences

Toxin        


Download         Length: 138 a.a.        Molecular weight: 16311.26 Da        Isoelectric Point: 10.7911

>T88502 WP_039275532.1 NZ_CP024780:c2530946-2530533 [Pectobacterium brasiliense]
VAQWRCDLRVSWRMQLLSLVVHGLLVLLILLAPWPDGYAWLWLCLVTMVMFGFIRSQRNIKSRQGEIVLLSETTLNWRQQ
EWQIVKRPWLLKNGVLLSLQAVNGKDKQQLWLASDSMGDDEWRHLRQILLQQKHWAR

Download         Length: 414 bp

>T88502 NZ_CP024780:c2530946-2530533 [Pectobacterium brasiliense]
GTGGCCCAGTGGCGATGTGACCTTCGCGTTTCCTGGCGCATGCAACTGTTATCATTGGTTGTGCATGGCCTATTAGTATT
GCTCATTCTGCTGGCACCCTGGCCGGACGGCTATGCGTGGCTATGGCTATGCCTGGTCACGATGGTGATGTTCGGTTTTA
TCCGTAGCCAACGGAATATTAAATCCCGACAGGGGGAAATCGTTCTGCTCAGCGAAACGACCCTGAACTGGCGGCAGCAG
GAATGGCAGATCGTTAAACGACCGTGGTTGCTGAAGAATGGCGTATTACTGTCATTGCAAGCGGTTAACGGTAAAGACAA
GCAGCAGCTGTGGCTGGCATCGGACAGCATGGGCGATGACGAATGGCGCCACTTGCGTCAAATTCTTTTGCAGCAGAAAC
ACTGGGCAAGATAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10507.94 Da        Isoelectric Point: 5.1392

>AT88502 WP_005971623.1 NZ_CP024780:c2531193-2530927 [Pectobacterium brasiliense]
MEIDNKSRIHWACRRGMRELDIAIMPFFEHDYDTLNDTDKRTFVRLLQSDDPDLFNWLMNHGEPEDGELKRMISLIQTRN
KDRGPVAM

Download         Length: 267 bp

>AT88502 NZ_CP024780:c2531193-2530927 [Pectobacterium brasiliense]
ATGGAAATCGATAATAAATCACGCATTCATTGGGCATGCCGCCGTGGTATGCGCGAATTGGATATCGCGATCATGCCGTT
TTTTGAGCATGACTATGACACACTTAATGACACTGATAAGCGCACGTTTGTACGCTTGTTACAAAGCGACGATCCCGATT
TATTCAACTGGCTGATGAACCACGGTGAACCGGAGGACGGAGAGCTGAAACGCATGATTTCCCTTATTCAGACGCGAAAT
AAAGATCGTGGCCCAGTGGCGATGTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A837DIN4

Antitoxin

Source ID Structure
AlphaFold DB A0A1D7Z1Z6

References