Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) tacAT/DUF1778(antitoxin)
Location 2252549..2253327 Replicon chromosome
Accession NZ_CP024780
Organism Pectobacterium brasiliense strain BZA12

Toxin (Protein)


Gene name TacT2 Uniprot ID -
Locus tag CTV95_RS10250 Protein ID WP_100017466.1
Coordinates 2252549..2253037 (-) Length 163 a.a.

Antitoxin (Protein)


Gene name TacA2 Uniprot ID -
Locus tag CTV95_RS10255 Protein ID WP_100017467.1
Coordinates 2253034..2253327 (-) Length 98 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CTV95_RS10210 2247613..2247807 - 195 WP_010299634.1 DUF3950 domain-containing protein -
CTV95_RS10215 2247993..2248334 + 342 WP_100017460.1 hypothetical protein -
CTV95_RS10225 2249241..2249984 + 744 WP_100017462.1 molybdopterin-guanine dinucleotide biosynthesis protein MobC -
CTV95_RS10230 2250043..2250261 + 219 WP_038903500.1 type II toxin-antitoxin system antitoxin CcdA -
CTV95_RS10235 2250264..2250569 + 306 WP_100017463.1 type II toxin-antitoxin system toxin CcdB -
CTV95_RS10240 2250676..2251725 - 1050 WP_100017464.1 hypothetical protein -
CTV95_RS10245 2251734..2252264 - 531 WP_100017465.1 response regulator -
CTV95_RS10250 2252549..2253037 - 489 WP_100017466.1 GNAT family N-acetyltransferase Toxin
CTV95_RS10255 2253034..2253327 - 294 WP_100017467.1 DUF1778 domain-containing protein Antitoxin
CTV95_RS10260 2253723..2253848 - 126 WP_100017468.1 helix-turn-helix domain-containing protein -
CTV95_RS10265 2253819..2254064 + 246 WP_100017469.1 type II toxin-antitoxin system antitoxin CcdA -
CTV95_RS10275 2254185..2254478 - 294 WP_100017470.1 DUF1778 domain-containing protein -
CTV95_RS10280 2254683..2255183 - 501 WP_014914371.1 serine acetyltransferase -
CTV95_RS10285 2255210..2256604 - 1395 WP_100017471.1 DUF4832 domain-containing protein -
CTV95_RS10290 2256643..2257050 - 408 WP_039510884.1 hypothetical protein -
CTV95_RS10295 2257053..2258165 - 1113 WP_100017472.1 glycosyltransferase family 4 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 2246162..2268740 22578


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

GNAT domain

(44-143)

Antitoxin

Vibrio phage ICP1, Orf50

(4-95)


Sequences

Toxin        


Download         Length: 163 a.a.        Molecular weight: 17430.37 Da        Isoelectric Point: 7.7792

>T88501 WP_100017466.1 NZ_CP024780:c2253037-2252549 [Pectobacterium brasiliense]
MISAPEPLRAGHILSSFCCGVESMDNWLKLRAMKNQVTGASRTFVSCDDSKVLAYYSLASSAVATNAAPGRFRRNMPDPI
PVVVLGRLAVDMSLHGQGVGRALVRDAGLRVIQVADIIGIRGMLVHALSDEARDFYLRVGFEPSPIDPMMLMVTLGDLVG
SI

Download         Length: 489 bp

>T88501 NZ_CP024780:c2253037-2252549 [Pectobacterium brasiliense]
ATGATTTCCGCCCCTGAGCCACTCCGCGCCGGACATATACTTTCCTCATTCTGTTGCGGCGTTGAGTCTATGGACAACTG
GCTAAAACTACGCGCGATGAAAAATCAGGTCACTGGCGCGTCACGAACTTTCGTCAGTTGCGATGATTCAAAAGTGTTGG
CGTATTACTCATTGGCTTCCAGTGCTGTGGCAACGAATGCCGCCCCCGGACGCTTTCGCCGCAATATGCCCGATCCGATC
CCGGTGGTAGTGCTGGGACGTCTGGCGGTGGATATGTCATTGCATGGTCAAGGTGTTGGCCGGGCATTGGTAAGAGATGC
TGGGCTAAGAGTTATTCAGGTGGCGGATATTATCGGCATTCGCGGGATGTTGGTTCATGCGCTGTCTGATGAAGCGCGAG
ATTTTTACCTACGGGTGGGATTTGAACCGTCACCGATAGATCCTATGATGCTGATGGTGACGTTGGGGGACTTGGTGGGG
AGTATTTAG

Antitoxin


Download         Length: 98 a.a.        Molecular weight: 10902.47 Da        Isoelectric Point: 10.1968

>AT88501 WP_100017467.1 NZ_CP024780:c2253327-2253034 [Pectobacterium brasiliense]
MPATNSVSVKRETLNLRIKPAERDLIDRAAKARGKNRTDFVLEAARAAAEEALIDQRIIMADPDAYQEFLARLDQTPSPN
AALRKTMQTPAPWEQKK

Download         Length: 294 bp

>AT88501 NZ_CP024780:c2253327-2253034 [Pectobacterium brasiliense]
ATGCCAGCGACGAACAGCGTTTCTGTTAAACGTGAAACACTAAATTTACGCATCAAACCCGCAGAACGCGATCTAATCGA
TCGTGCTGCGAAGGCCAGAGGAAAAAATCGCACTGATTTTGTTCTTGAGGCTGCGCGTGCCGCCGCAGAAGAGGCGTTGA
TCGATCAGCGCATCATCATGGCAGATCCCGATGCTTATCAGGAATTCCTTGCTCGCTTGGATCAAACTCCCTCGCCGAAT
GCCGCGTTGCGCAAAACCATGCAAACACCTGCACCGTGGGAACAGAAAAAATGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References