Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) Hha-TomB/-
Location 1996725..1997350 Replicon chromosome
Accession NZ_CP024780
Organism Pectobacterium brasiliense strain BZA12

Toxin (Protein)


Gene name Hha Uniprot ID C6DB72
Locus tag CTV95_RS09135 Protein ID WP_005976087.1
Coordinates 1997147..1997350 (+) Length 68 a.a.

Antitoxin (Protein)


Gene name TomB Uniprot ID Q6D809
Locus tag CTV95_RS09130 Protein ID WP_010282247.1
Coordinates 1996725..1997093 (+) Length 123 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CTV95_RS09115 1992356..1995484 + 3129 WP_100017380.1 efflux RND transporter permease subunit -
CTV95_RS09120 1995717..1995965 + 249 WP_014914542.1 type B 50S ribosomal protein L31 -
CTV95_RS09125 1995983..1996126 + 144 WP_005976091.1 type B 50S ribosomal protein L36 -
CTV95_RS09130 1996725..1997093 + 369 WP_010282247.1 Hha toxicity modulator TomB Antitoxin
CTV95_RS09135 1997147..1997350 + 204 WP_005976087.1 hemolysin expression modulator Hha Toxin
CTV95_RS09145 1998214..1998534 + 321 WP_010282239.1 MGMT family protein -
CTV95_RS09150 1998554..1999135 - 582 WP_014914539.1 YbaY family lipoprotein -
CTV95_RS09155 1999348..2000211 + 864 WP_014914538.1 acyl-CoA thioesterase II -
CTV95_RS09160 2000351..2001637 - 1287 WP_014914537.1 ammonium transporter AmtB -
CTV95_RS09165 2001677..2002015 - 339 WP_002208627.1 P-II family nitrogen regulator -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Haemolysin expression modulating, HHA

(8-64)

Antitoxin

Biofilm formation regulator YbaJ

(1-118)


Sequences

Toxin        


Download         Length: 68 a.a.        Molecular weight: 8145.52 Da        Isoelectric Point: 8.9008

>T88499 WP_005976087.1 NZ_CP024780:1997147-1997350 [Pectobacterium brasiliense]
MKKIDYLMRLRKCTTIDTLERVIEKNKYELSNDELEMFFSAADHRLAELTMNKLYDKVPTAVWRYVR

Download         Length: 204 bp

>T88499 NZ_CP024780:1997147-1997350 [Pectobacterium brasiliense]
ATGAAAAAAATCGACTATTTGATGCGTTTGCGTAAATGCACAACCATTGACACTCTCGAACGCGTTATTGAAAAAAACAA
GTATGAACTCTCTAATGATGAACTGGAGATGTTCTTTTCCGCAGCCGATCATCGCCTGGCAGAACTGACGATGAACAAAC
TCTACGACAAAGTCCCTACTGCAGTATGGCGATACGTTCGTTAA

Antitoxin


Download         Length: 123 a.a.        Molecular weight: 14046.80 Da        Isoelectric Point: 4.4787

>AT88499 WP_010282247.1 NZ_CP024780:1996725-1997093 [Pectobacterium brasiliense]
MDEYTPKHYDIAQLRFLCENLCDESIATLGDSSHGWVNDPTSAINLQLNELIEHIATFILTFKIKYPNESELSEQVEKYL
DDTYVLFSNYGINDAELRRWQKSKAKLFGMFSGENICTPAKT

Download         Length: 369 bp

>AT88499 NZ_CP024780:1996725-1997093 [Pectobacterium brasiliense]
ATGGATGAGTACACACCAAAACATTATGATATTGCCCAACTCAGATTCTTATGTGAGAATCTGTGTGACGAAAGCATAGC
GACGTTAGGCGATAGCAGTCACGGCTGGGTCAATGATCCAACATCTGCGATCAATCTCCAATTAAATGAACTTATTGAGC
ATATCGCTACGTTTATTCTCACATTTAAAATAAAATACCCTAACGAAAGTGAGCTTTCAGAGCAGGTTGAAAAGTATTTG
GATGATACTTACGTCTTGTTTAGCAACTATGGTATTAATGATGCTGAACTACGGCGTTGGCAGAAGTCCAAAGCAAAATT
ATTCGGAATGTTCTCAGGGGAGAACATCTGTACGCCTGCTAAAACTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A1D7Z3F0

Antitoxin

Source ID Structure
AlphaFold DB A0A086EI31

References