Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 1666797..1667350 Replicon chromosome
Accession NZ_CP024780
Organism Pectobacterium brasiliense strain BZA12

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag CTV95_RS07635 Protein ID WP_100017271.1
Coordinates 1666797..1667111 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag CTV95_RS07640 Protein ID WP_100017272.1
Coordinates 1667114..1667350 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CTV95_RS07615 1663371..1664303 - 933 WP_100017266.1 hypothetical protein -
CTV95_RS07620 1664307..1665302 - 996 WP_100017268.1 nucleotidyltransferase -
CTV95_RS07625 1665452..1666351 - 900 WP_100017269.1 SMEK domain-containing protein -
CTV95_RS07630 1666467..1666763 + 297 WP_100017270.1 mobilization protein mobC -
CTV95_RS07635 1666797..1667111 - 315 WP_100017271.1 CcdB family protein Toxin
CTV95_RS07640 1667114..1667350 - 237 WP_100017272.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
CTV95_RS07645 1667670..1668614 - 945 WP_100017273.1 DUF1738 domain-containing protein -
CTV95_RS07650 1669095..1669391 + 297 WP_100017274.1 DUF3892 domain-containing protein -
CTV95_RS07655 1669596..1670198 - 603 WP_065684227.1 tyrosine-type recombinase/integrase -
CTV95_RS07660 1670383..1671969 - 1587 WP_157765229.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Integrative and Conjugative Element - - 1631731..1673904 42173


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11563.53 Da        Isoelectric Point: 7.9859

>T88498 WP_100017271.1 NZ_CP024780:c1667111-1666797 [Pectobacterium brasiliense]
MQFTVYGNTGKSVIYPLLLDVTSDIIGQLNRRIVIPLLPIEKYPAGRRPDRLVPVIRLTDGKEYAVMTHELASIPVQALG
AVFCDASQYRTQVKAAIDFLIDGF

Download         Length: 315 bp

>T88498 NZ_CP024780:c1667111-1666797 [Pectobacterium brasiliense]
ATGCAATTCACTGTATACGGTAATACCGGGAAAAGCGTCATTTACCCGCTGTTGCTCGATGTCACGAGCGATATTATCGG
GCAATTGAATCGTCGGATAGTAATCCCATTGCTCCCTATTGAAAAGTATCCGGCAGGCCGCCGACCAGATCGCCTTGTCC
CCGTCATCAGGCTGACGGATGGCAAAGAATACGCCGTAATGACCCACGAGCTGGCCAGTATCCCTGTCCAGGCTCTGGGT
GCGGTGTTTTGTGATGCGTCGCAGTACCGTACTCAGGTAAAGGCTGCAATAGACTTCCTCATCGATGGGTTCTGA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 8983.05 Da        Isoelectric Point: 7.1672

>AT88498 WP_100017272.1 NZ_CP024780:c1667350-1667114 [Pectobacterium brasiliense]
MTGKQRNTQSVTMTVERALLVRAREAGINLSATLTTALDAELRRHEAKKWQEENREALAALNRFHDEQGCFSDEYRTF

Download         Length: 237 bp

>AT88498 NZ_CP024780:c1667350-1667114 [Pectobacterium brasiliense]
ATGACCGGGAAACAACGCAACACGCAGAGCGTGACCATGACAGTAGAACGTGCCTTACTGGTAAGAGCGCGTGAAGCGGG
CATTAATCTGAGTGCTACCCTGACAACCGCCCTGGATGCAGAGCTTCGCCGTCATGAAGCGAAAAAATGGCAGGAAGAAA
ACAGGGAGGCTCTCGCAGCACTAAATCGTTTTCATGATGAGCAGGGTTGTTTCAGCGATGAATACAGGACGTTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References