Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) ccdAB/CcdA(antitoxin)
Location 1494524..1495077 Replicon chromosome
Accession NZ_CP024780
Organism Pectobacterium brasiliense strain BZA12

Toxin (Protein)


Gene name ccdB Uniprot ID -
Locus tag CTV95_RS06870 Protein ID WP_039558371.1
Coordinates 1494524..1494838 (-) Length 105 a.a.

Antitoxin (Protein)


Gene name ccdA Uniprot ID -
Locus tag CTV95_RS06875 Protein ID WP_039558370.1
Coordinates 1494841..1495077 (-) Length 79 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CTV95_RS06830 1490459..1490626 - 168 WP_010280855.1 YqaE/Pmp3 family membrane protein -
CTV95_RS06835 1491068..1491664 + 597 WP_039287353.1 YolA family protein -
CTV95_RS06840 1491719..1492198 - 480 WP_100017132.1 hypothetical protein -
CTV95_RS06845 1492441..1492827 + 387 WP_040034858.1 lysozyme inhibitor LprI family protein -
CTV95_RS06850 1493068..1493865 + 798 WP_040034856.1 DgsA anti-repressor MtfA -
CTV95_RS06860 1494225..1494389 + 165 Protein_1339 DUF4102 domain-containing protein -
CTV95_RS06870 1494524..1494838 - 315 WP_039558371.1 CcdB family protein Toxin
CTV95_RS06875 1494841..1495077 - 237 WP_039558370.1 type II toxin-antitoxin system CcdA family antitoxin Antitoxin
CTV95_RS06880 1495397..1496341 - 945 WP_040034854.1 DUF1738 domain-containing protein -
CTV95_RS06885 1496727..1497449 + 723 WP_072014229.1 MurR/RpiR family transcriptional regulator -
CTV95_RS06890 1497627..1499054 + 1428 WP_010284508.1 glycoside hydrolase family 1 protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Genomic island - - 1490459..1505982 15523


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin CcdB

(2-103)

Antitoxin

Post-segregation antitoxin CcdA

(9-78)


Sequences

Toxin        


Download         Length: 105 a.a.        Molecular weight: 11466.37 Da        Isoelectric Point: 6.9727

>T88496 WP_039558371.1 NZ_CP024780:c1494838-1494524 [Pectobacterium brasiliense]
MQFTVYGNTGKSVVYPLLLDVTSDIIGQLNRRIVIPLLPIEKYPAGRRPDRLVPVVTLTDGKEYAVMTHELASIPVQALG
AVFCDASQYRSQVKAAIDFLIDGF

Download         Length: 315 bp

>T88496 NZ_CP024780:c1494838-1494524 [Pectobacterium brasiliense]
ATGCAATTCACTGTATACGGTAATACTGGGAAAAGCGTCGTTTACCCGCTGTTGCTCGATGTCACGAGCGATATTATTGG
ACAATTGAATCGTCGGATAGTGATCCCATTGCTCCCTATTGAAAAGTATCCGGCAGGCCGCCGACCGGATCGCCTTGTCC
CCGTCGTCACGCTGACGGACGGCAAAGAATACGCCGTAATGACCCACGAGCTGGCAAGTATCCCTGTCCAGGCCCTGGGT
GCGGTGTTTTGTGATGCTTCGCAGTACCGTTCTCAGGTAAAGGCTGCAATAGACTTCCTCATCGACGGGTTCTGA

Antitoxin


Download         Length: 79 a.a.        Molecular weight: 9041.08 Da        Isoelectric Point: 6.4631

>AT88496 WP_039558370.1 NZ_CP024780:c1495077-1494841 [Pectobacterium brasiliense]
MTAKQRNTQSVTMTVERALLVRAREVGINLSATLSTALDAELRRHEAKKWQEENREAIDALNRFHDENGCFSDEYRTF

Download         Length: 237 bp

>AT88496 NZ_CP024780:c1495077-1494841 [Pectobacterium brasiliense]
ATGACCGCGAAACAACGCAACACGCAGAGCGTGACCATGACGGTGGAGCGTGCCTTACTGGTAAGAGCGCGTGAAGTGGG
TATTAACCTGAGTGCTACTCTGTCAACCGCACTGGATGCGGAGCTTCGCCGTCATGAAGCGAAAAAATGGCAGGAAGAAA
ACAGGGAGGCTATCGACGCATTAAATCGTTTTCATGATGAAAACGGCTGTTTCAGTGATGAATACAGGACGTTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References