Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-Axe/YoeB-RelB
Location 1452301..1452808 Replicon chromosome
Accession NZ_CP024749
Organism Fusobacterium nucleatum subsp. vincentii strain KCOM 2931

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag CS401_RS07055 Protein ID WP_100028242.1
Coordinates 1452548..1452808 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag CS401_RS07050 Protein ID WP_100028241.1
Coordinates 1452301..1452555 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CS401_RS07035 1448947..1449309 + 363 WP_100028238.1 arsenate reductase family protein -
CS401_RS07040 1449457..1450731 + 1275 WP_100028239.1 branched-chain amino acid transport system II carrier protein -
CS401_RS07045 1450965..1452173 + 1209 WP_147383279.1 tyrosine--tRNA ligase -
CS401_RS07050 1452301..1452555 + 255 WP_100028241.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CS401_RS07055 1452548..1452808 + 261 WP_100028242.1 Txe/YoeB family addiction module toxin Toxin
CS401_RS07060 1452825..1453307 + 483 WP_100028587.1 GNAT family N-acetyltransferase -
CS401_RS07065 1453498..1454148 + 651 WP_023035894.1 endonuclease III -
CS401_RS07070 1454227..1455423 + 1197 WP_008796538.1 cysteine desulfurase NifS -
CS401_RS07075 1455496..1455882 + 387 WP_008796539.1 Fe-S cluster assembly scaffold protein NifU -
CS401_RS07080 1455966..1457243 + 1278 WP_100028243.1 D-alanyl-D-alanine carboxypeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(6-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10323.83 Da        Isoelectric Point: 9.3654

>T88492 WP_100028242.1 NZ_CP024749:1452548-1452808 [Fusobacterium nucleatum subsp. vincentii]
MNNLVWTHKAWQDYLYWQTQDKKTLKKINELVKDIERNGALNGIGKPEVLKNENAYSRRIDEKNRLVYRIVDGFIWIIAC
KGHYEE

Download         Length: 261 bp

>T88492 NZ_CP024749:1452548-1452808 [Fusobacterium nucleatum subsp. vincentii]
ATGAATAATTTAGTATGGACACATAAGGCTTGGCAAGATTACCTATATTGGCAAACTCAAGATAAAAAAACTTTAAAGAA
GATAAATGAATTAGTCAAAGATATTGAAAGAAATGGAGCTTTAAATGGGATAGGCAAGCCAGAAGTATTAAAAAATGAAA
ATGCATATAGTAGGAGAATTGATGAAAAAAATAGACTAGTTTATAGAATTGTAGACGGGTTTATATGGATAATTGCTTGT
AAAGGTCATTATGAGGAATAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9796.12 Da        Isoelectric Point: 4.4453

>AT88492 WP_100028241.1 NZ_CP024749:1452301-1452555 [Fusobacterium nucleatum subsp. vincentii]
MLAINYTTLRTNLKSYFDKAVDNDEDIIITRKNERNVVLLSLDKYNEFLKAMRNLEYMTKIREGIAELEAGKGEIHDLIE
ADDE

Download         Length: 255 bp

>AT88492 NZ_CP024749:1452301-1452555 [Fusobacterium nucleatum subsp. vincentii]
ATGTTAGCAATTAATTATACAACTTTGAGAACCAATTTAAAAAGCTATTTTGATAAAGCAGTAGATAATGATGAAGATAT
TATTATAACAAGAAAAAATGAAAGAAATGTTGTTCTATTAAGTCTTGATAAATATAATGAGTTTTTAAAAGCTATGAGAA
ATCTTGAATATATGACAAAAATAAGAGAAGGAATAGCTGAATTAGAGGCAGGAAAAGGAGAAATCCATGATTTAATAGAG
GCTGATGATGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References