Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 4713857..4714125 Replicon chromosome
Accession NZ_CP024717
Organism Escherichia coli strain LS4

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 4713985..4714087 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 4713857..4714125 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CUB99_RS24430 4710410..4711072 - 663 WP_000944256.1 exodeoxyribonuclease X -
CUB99_RS24435 4711096..4711752 - 657 WP_000011664.1 carbon-nitrogen hydrolase family protein -
CUB99_RS24440 4711854..4712084 - 231 WP_000916763.1 DNA polymerase III subunit theta -
CUB99_RS24445 4712223..4712597 + 375 WP_000168747.1 CopC domain-containing protein YobA -
CUB99_RS24450 4712601..4713473 + 873 WP_000879317.1 copper homeostasis membrane protein CopD -
CUB99_RS24455 4713486..4713827 + 342 WP_000976472.1 YebY family protein -
- 4713857..4714125 - 269 - - Antitoxin
- 4713985..4714087 + 103 - - Toxin
CUB99_RS24460 4714222..4714878 + 657 WP_000812745.1 protein-serine/threonine phosphatase -
CUB99_RS24465 4714879..4715070 - 192 WP_001296140.1 YebW family protein -
CUB99_RS24470 4715175..4715411 - 237 WP_001295499.1 DUF1480 family protein -
CUB99_RS24475 4715528..4716967 - 1440 WP_001296139.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T88445 NZ_CP024717:4713985-4714087 [Escherichia coli]
GCAAGGCAACTAAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTGTTCGGTCTCTTTTT

Antitoxin


Download         Length: 269 bp

>AT88445 NZ_CP024717:c4714125-4713857 [Escherichia coli]
AAAGTCAGCGAAGGGAATGCTTCTGGCTTTTAACAGATAAAAAGAGACCGAACACGATTCCTGTATTCGGTCCAGGGAAA
TGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGGCATTAATGCAGGCTTAGTTGCCTTGCTCTTTAAGAATAGATGACG
ACGCCAGGTTTTCCAGTTTGCGTGCAAAATGGTCAATAAAAAGCGTGGTGGTCATCAGCTTAAATATTAAAAACCGCCCG
TTCTGGTGAAAGAACTGAGGCGGTTTTTT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References