Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/RHH(antitoxin) |
Location | 5409612..5410153 | Replicon | chromosome |
Accession | NZ_CP024712 | ||
Organism | Pseudomonas syringae pv. actinidiae strain MAFF212063 |
Toxin (Protein)
Gene name | relE | Uniprot ID | A0A0K8LVV5 |
Locus tag | CT122_RS25310 | Protein ID | WP_017683357.1 |
Coordinates | 5409878..5410153 (+) | Length | 92 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | A0A0K8LU58 |
Locus tag | CT122_RS25305 | Protein ID | WP_003382249.1 |
Coordinates | 5409612..5409878 (+) | Length | 89 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CT122_RS25295 | 5406333..5408255 | + | 1923 | WP_099978995.1 | methyl-accepting chemotaxis protein | - |
CT122_RS25300 | 5408554..5409531 | - | 978 | WP_100006011.1 | IS5 family transposase | - |
CT122_RS25305 | 5409612..5409878 | + | 267 | WP_003382249.1 | ribbon-helix-helix domain-containing protein | Antitoxin |
CT122_RS25310 | 5409878..5410153 | + | 276 | WP_017683357.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
CT122_RS25325 | 5410725..5411993 | + | 1269 | WP_007244158.1 | OprD family porin | - |
CT122_RS25330 | 5412172..5412996 | + | 825 | WP_003380380.1 | NAD(P)-dependent oxidoreductase | - |
CT122_RS25335 | 5413056..5413940 | + | 885 | WP_099978173.1 | SMP-30/gluconolactonase/LRE family protein | - |
CT122_RS25340 | 5413997..5415022 | + | 1026 | WP_019332509.1 | TRAP transporter substrate-binding protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|---|---|---|---|---|---|---|
- | flank | IS/Tn | - | - | 5408554..5409531 | 977 |
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 92 a.a. Molecular weight: 10770.41 Da Isoelectric Point: 7.0123
>T88425 WP_017683357.1 NZ_CP024712:5409878-5410153 [Pseudomonas syringae pv. actinidiae]
MELMWTSKTLSDVTRLYDFLAVANQPAAAQTAQKLTAAPIMLLSNPRIGERLEEFEPRDVRRIQIGRYEMRYEIVDSTIY
LLRLWHTREDR
MELMWTSKTLSDVTRLYDFLAVANQPAAAQTAQKLTAAPIMLLSNPRIGERLEEFEPRDVRRIQIGRYEMRYEIVDSTIY
LLRLWHTREDR
Download Length: 276 bp
>T88425 NZ_CP024712:5409878-5410153 [Pseudomonas syringae pv. actinidiae]
ATGGAGCTGATGTGGACAAGCAAAACGCTATCTGACGTCACCCGCCTGTATGATTTTTTAGCGGTAGCAAACCAGCCCGC
TGCCGCCCAGACCGCACAGAAGCTTACAGCGGCGCCGATCATGCTCCTTTCCAACCCGCGGATTGGTGAGCGTCTGGAGG
AGTTTGAGCCCCGGGATGTGCGCAGAATTCAGATAGGCCGCTATGAAATGCGCTACGAAATTGTGGACTCAACAATTTAT
CTGTTGCGGCTGTGGCATACACGCGAGGATCGGTAA
ATGGAGCTGATGTGGACAAGCAAAACGCTATCTGACGTCACCCGCCTGTATGATTTTTTAGCGGTAGCAAACCAGCCCGC
TGCCGCCCAGACCGCACAGAAGCTTACAGCGGCGCCGATCATGCTCCTTTCCAACCCGCGGATTGGTGAGCGTCTGGAGG
AGTTTGAGCCCCGGGATGTGCGCAGAATTCAGATAGGCCGCTATGAAATGCGCTACGAAATTGTGGACTCAACAATTTAT
CTGTTGCGGCTGTGGCATACACGCGAGGATCGGTAA
Antitoxin
Download Length: 89 a.a. Molecular weight: 9934.24 Da Isoelectric Point: 5.7066
>AT88425 WP_003382249.1 NZ_CP024712:5409612-5409878 [Pseudomonas syringae pv. actinidiae]
MTTKTRSVTAHIPEQLAEKVDLMAERLERSKNWIVKQALSAWIDQEEERSRLTREALADVDAGRVIDHQAVQAWADSLST
ATPLPVPR
MTTKTRSVTAHIPEQLAEKVDLMAERLERSKNWIVKQALSAWIDQEEERSRLTREALADVDAGRVIDHQAVQAWADSLST
ATPLPVPR
Download Length: 267 bp
>AT88425 NZ_CP024712:5409612-5409878 [Pseudomonas syringae pv. actinidiae]
ATGACAACCAAGACCCGATCTGTAACAGCTCACATACCCGAACAATTGGCTGAAAAAGTCGACCTGATGGCAGAGCGACT
CGAACGCTCTAAAAACTGGATCGTCAAACAGGCCTTGTCTGCATGGATAGATCAGGAGGAAGAACGTAGTCGCCTCACTC
GCGAAGCATTAGCCGATGTCGATGCTGGCCGTGTGATTGACCATCAGGCTGTTCAGGCCTGGGCTGACAGTTTAAGCACC
GCTACGCCTCTGCCGGTTCCGCGCTGA
ATGACAACCAAGACCCGATCTGTAACAGCTCACATACCCGAACAATTGGCTGAAAAAGTCGACCTGATGGCAGAGCGACT
CGAACGCTCTAAAAACTGGATCGTCAAACAGGCCTTGTCTGCATGGATAGATCAGGAGGAAGAACGTAGTCGCCTCACTC
GCGAAGCATTAGCCGATGTCGATGCTGGCCGTGTGATTGACCATCAGGCTGTTCAGGCCTGGGCTGACAGTTTAAGCACC
GCTACGCCTCTGCCGGTTCCGCGCTGA
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0K8LVV5 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0K8LU58 |