Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RHH(antitoxin)
Location 5409612..5410153 Replicon chromosome
Accession NZ_CP024712
Organism Pseudomonas syringae pv. actinidiae strain MAFF212063

Toxin (Protein)


Gene name relE Uniprot ID A0A0K8LVV5
Locus tag CT122_RS25310 Protein ID WP_017683357.1
Coordinates 5409878..5410153 (+) Length 92 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0K8LU58
Locus tag CT122_RS25305 Protein ID WP_003382249.1
Coordinates 5409612..5409878 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CT122_RS25295 5406333..5408255 + 1923 WP_099978995.1 methyl-accepting chemotaxis protein -
CT122_RS25300 5408554..5409531 - 978 WP_100006011.1 IS5 family transposase -
CT122_RS25305 5409612..5409878 + 267 WP_003382249.1 ribbon-helix-helix domain-containing protein Antitoxin
CT122_RS25310 5409878..5410153 + 276 WP_017683357.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CT122_RS25325 5410725..5411993 + 1269 WP_007244158.1 OprD family porin -
CT122_RS25330 5412172..5412996 + 825 WP_003380380.1 NAD(P)-dependent oxidoreductase -
CT122_RS25335 5413056..5413940 + 885 WP_099978173.1 SMP-30/gluconolactonase/LRE family protein -
CT122_RS25340 5413997..5415022 + 1026 WP_019332509.1 TRAP transporter substrate-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- flank IS/Tn - - 5408554..5409531 977


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(4-90)

Antitoxin

Ribbon-helix-helix protein, CopG

(8-45)


Sequences

Toxin        


Download         Length: 92 a.a.        Molecular weight: 10770.41 Da        Isoelectric Point: 7.0123

>T88425 WP_017683357.1 NZ_CP024712:5409878-5410153 [Pseudomonas syringae pv. actinidiae]
MELMWTSKTLSDVTRLYDFLAVANQPAAAQTAQKLTAAPIMLLSNPRIGERLEEFEPRDVRRIQIGRYEMRYEIVDSTIY
LLRLWHTREDR

Download         Length: 276 bp

>T88425 NZ_CP024712:5409878-5410153 [Pseudomonas syringae pv. actinidiae]
ATGGAGCTGATGTGGACAAGCAAAACGCTATCTGACGTCACCCGCCTGTATGATTTTTTAGCGGTAGCAAACCAGCCCGC
TGCCGCCCAGACCGCACAGAAGCTTACAGCGGCGCCGATCATGCTCCTTTCCAACCCGCGGATTGGTGAGCGTCTGGAGG
AGTTTGAGCCCCGGGATGTGCGCAGAATTCAGATAGGCCGCTATGAAATGCGCTACGAAATTGTGGACTCAACAATTTAT
CTGTTGCGGCTGTGGCATACACGCGAGGATCGGTAA

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 9934.24 Da        Isoelectric Point: 5.7066

>AT88425 WP_003382249.1 NZ_CP024712:5409612-5409878 [Pseudomonas syringae pv. actinidiae]
MTTKTRSVTAHIPEQLAEKVDLMAERLERSKNWIVKQALSAWIDQEEERSRLTREALADVDAGRVIDHQAVQAWADSLST
ATPLPVPR

Download         Length: 267 bp

>AT88425 NZ_CP024712:5409612-5409878 [Pseudomonas syringae pv. actinidiae]
ATGACAACCAAGACCCGATCTGTAACAGCTCACATACCCGAACAATTGGCTGAAAAAGTCGACCTGATGGCAGAGCGACT
CGAACGCTCTAAAAACTGGATCGTCAAACAGGCCTTGTCTGCATGGATAGATCAGGAGGAAGAACGTAGTCGCCTCACTC
GCGAAGCATTAGCCGATGTCGATGCTGGCCGTGTGATTGACCATCAGGCTGTTCAGGCCTGGGCTGACAGTTTAAGCACC
GCTACGCCTCTGCCGGTTCCGCGCTGA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K8LVV5

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8LU58

References