Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-YafN
Location 1806543..1807068 Replicon chromosome
Accession NZ_CP024712
Organism Pseudomonas syringae pv. actinidiae strain MAFF212063

Toxin (Protein)


Gene name relE Uniprot ID A0A0K8M609
Locus tag CT122_RS08365 Protein ID WP_017684329.1
Coordinates 1806543..1806833 (-) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID A0A0K8M645
Locus tag CT122_RS08370 Protein ID WP_017684328.1
Coordinates 1806823..1807068 (-) Length 82 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CT122_RS08345 1801815..1802285 - 471 WP_003382605.1 MaoC family dehydratase -
CT122_RS08355 1802681..1804369 + 1689 WP_003382606.1 long-chain-fatty-acid--CoA ligase FadD2 -
CT122_RS08360 1804724..1806415 + 1692 WP_003382607.1 long-chain-fatty-acid--CoA ligase FadD1 -
CT122_RS08365 1806543..1806833 - 291 WP_017684329.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CT122_RS08370 1806823..1807068 - 246 WP_017684328.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CT122_RS08375 1807241..1811152 + 3912 WP_099979114.1 ATP-dependent RNA helicase HrpA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-83)

Antitoxin


No domain identified.



Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11019.86 Da        Isoelectric Point: 10.4180

>T88423 WP_017684329.1 NZ_CP024712:c1806833-1806543 [Pseudomonas syringae pv. actinidiae]
MTFKLEFLPSALKEWKKLGHTVSAQLKKKLLERLELPRNAGDALHGMPDHYKIKLRSAGYRLVYRVEDDRVVVTVVAVGK
RERGDIYDSAKDRLSP

Download         Length: 291 bp

>T88423 NZ_CP024712:c1806833-1806543 [Pseudomonas syringae pv. actinidiae]
TTGACCTTTAAGCTCGAGTTTCTGCCTTCAGCCCTGAAAGAGTGGAAAAAACTGGGGCATACCGTTAGTGCTCAACTCAA
GAAAAAGCTTTTGGAGCGGCTCGAATTACCTCGAAATGCGGGCGATGCGCTGCATGGCATGCCCGATCACTACAAAATCA
AGTTGCGCAGTGCTGGTTACAGACTGGTTTACCGGGTGGAAGATGATCGGGTAGTAGTGACCGTCGTCGCTGTAGGCAAG
CGCGAACGAGGCGATATCTACGATTCAGCCAAGGACAGGCTGTCTCCCTGA

Antitoxin


Download         Length: 82 a.a.        Molecular weight: 8860.38 Da        Isoelectric Point: 4.9721

>AT88423 WP_017684328.1 NZ_CP024712:c1807068-1806823 [Pseudomonas syringae pv. actinidiae]
MQNIFADIAVSVSELKKNPSAVLSGAQGLPVAVLNHNKVMGYMVPAEVFEAMMKRLDDLDLADLIKARQHEKPVSVDILD
L

Download         Length: 246 bp

>AT88423 NZ_CP024712:c1807068-1806823 [Pseudomonas syringae pv. actinidiae]
ATGCAAAATATCTTTGCGGACATCGCGGTCAGCGTCTCTGAACTGAAGAAAAACCCGTCAGCCGTCCTGAGCGGCGCACA
AGGCTTGCCCGTCGCAGTACTCAATCACAATAAAGTCATGGGCTACATGGTGCCTGCCGAGGTGTTTGAAGCAATGATGA
AGCGCCTTGATGACCTCGATCTGGCCGACCTGATCAAAGCCAGGCAACATGAAAAGCCGGTATCGGTAGATATACTTGAC
CTTTAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K8M609

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8M645

References