Detailed information of TA system
Bioinformatically predictedOverview
TA module
Type | II | Classification (family/domain) | relBE/ParE-RelB |
Location | 271738..272257 | Replicon | chromosome |
Accession | NZ_CP024712 | ||
Organism | Pseudomonas syringae pv. actinidiae strain MAFF212063 |
Toxin (Protein)
Gene name | relE | Uniprot ID | S6W9N2 |
Locus tag | CT122_RS01185 | Protein ID | WP_017684310.1 |
Coordinates | 271967..272257 (+) | Length | 97 a.a. |
Antitoxin (Protein)
Gene name | relB | Uniprot ID | S6UWW5 |
Locus tag | CT122_RS01180 | Protein ID | WP_002551444.1 |
Coordinates | 271738..271977 (+) | Length | 80 a.a. |
Genomic Context
Locus tag | Coordinates | Strand | Size (bp) | Protein ID | Product | Description |
---|---|---|---|---|---|---|
CT122_RS01150 | 266919..267266 | - | 348 | WP_017684314.1 | helix-turn-helix domain-containing protein | - |
CT122_RS01155 | 267539..268033 | - | 495 | WP_005621707.1 | hypothetical protein | - |
CT122_RS01160 | 268193..268732 | + | 540 | WP_099978976.1 | GNAT family N-acetyltransferase | - |
CT122_RS01165 | 268920..269552 | + | 633 | WP_057436493.1 | DUF4062 domain-containing protein | - |
CT122_RS01170 | 269545..270984 | + | 1440 | WP_017710283.1 | putative DNA binding domain-containing protein | - |
CT122_RS01175 | 271104..271562 | + | 459 | WP_099978975.1 | GNAT family N-acetyltransferase | - |
CT122_RS01180 | 271738..271977 | + | 240 | WP_002551444.1 | type II toxin-antitoxin system RelB/DinJ family antitoxin | Antitoxin |
CT122_RS01185 | 271967..272257 | + | 291 | WP_017684310.1 | type II toxin-antitoxin system RelE/ParE family toxin | Toxin |
CT122_RS01195 | 272483..273220 | - | 738 | WP_099978974.1 | hypothetical protein | - |
CT122_RS01200 | 273577..273918 | + | 342 | WP_003380754.1 | hypothetical protein | - |
CT122_RS01205 | 273995..274607 | + | 613 | Protein_225 | histidine phosphatase family protein | - |
CT122_RS01210 | 274788..275030 | + | 243 | WP_003380750.1 | hypothetical protein | - |
CT122_RS01215 | 275020..275303 | + | 284 | Protein_227 | type II toxin-antitoxin system RelE/ParE family toxin | - |
CT122_RS01220 | 275367..275909 | - | 543 | WP_020312301.1 | hypothetical protein | - |
Associated MGEs
MGE detail |
Similar MGEs |
Relative position |
MGE Type | Cargo ARG | Virulence gene | Coordinates | Length (bp) |
---|
Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.
Sequences
Toxin
Download Length: 97 a.a. Molecular weight: 11145.98 Da Isoelectric Point: 10.0984
>T88422 WP_017684310.1 NZ_CP024712:271967-272257 [Pseudomonas syringae pv. actinidiae]
MTYSLEFDARALKEWHKLGDTVRQQLKKKLATILVAPRVEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVVVFVVAVDK
RERDEVYRKAADRLGG
MTYSLEFDARALKEWHKLGDTVRQQLKKKLATILVAPRVEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVVVFVVAVDK
RERDEVYRKAADRLGG
Download Length: 291 bp
>T88422 NZ_CP024712:271967-272257 [Pseudomonas syringae pv. actinidiae]
ATGACTTATAGCCTCGAATTTGATGCGCGAGCTCTGAAGGAATGGCACAAATTAGGCGATACCGTGCGTCAGCAGCTCAA
GAAAAAGCTGGCTACGATTCTGGTTGCTCCGCGTGTTGAAGCAAATCGCCTGCATGCGTTGCCCGACTGCTACAAAATCA
AGCTGCGCAGCAGCGGCTATCGGCTGGTTTATCAGGTTATTGACCAAGAGGTTGTGGTCTTCGTGGTTGCTGTGGACAAG
CGTGAGCGAGATGAGGTTTACCGTAAGGCGGCTGATCGGTTGGGTGGGTAA
ATGACTTATAGCCTCGAATTTGATGCGCGAGCTCTGAAGGAATGGCACAAATTAGGCGATACCGTGCGTCAGCAGCTCAA
GAAAAAGCTGGCTACGATTCTGGTTGCTCCGCGTGTTGAAGCAAATCGCCTGCATGCGTTGCCCGACTGCTACAAAATCA
AGCTGCGCAGCAGCGGCTATCGGCTGGTTTATCAGGTTATTGACCAAGAGGTTGTGGTCTTCGTGGTTGCTGTGGACAAG
CGTGAGCGAGATGAGGTTTACCGTAAGGCGGCTGATCGGTTGGGTGGGTAA
Antitoxin
Download Length: 80 a.a. Molecular weight: 8955.34 Da Isoelectric Point: 4.6017
>AT88422 WP_002551444.1 NZ_CP024712:271738-271977 [Pseudomonas syringae pv. actinidiae]
MASINVRIDDDLKARAYLELEKLGVTPSELLRQTLQYVAERGQLPFKTVLMTEEDEALLATVRERLAAPQRVKVSLDDL
MASINVRIDDDLKARAYLELEKLGVTPSELLRQTLQYVAERGQLPFKTVLMTEEDEALLATVRERLAAPQRVKVSLDDL
Download Length: 240 bp
>AT88422 NZ_CP024712:271738-271977 [Pseudomonas syringae pv. actinidiae]
ATGGCGTCTATTAATGTTCGTATCGACGACGATCTCAAGGCTCGTGCTTATCTCGAGCTTGAAAAGCTTGGCGTCACCCC
TTCGGAACTGCTGCGCCAAACCCTGCAGTACGTGGCAGAGCGCGGCCAGTTGCCGTTCAAGACCGTACTGATGACCGAGG
AAGACGAAGCCTTGCTTGCAACAGTGCGCGAGCGCCTTGCGGCTCCGCAACGGGTCAAGGTTTCACTGGATGACTTATAG
ATGGCGTCTATTAATGTTCGTATCGACGACGATCTCAAGGCTCGTGCTTATCTCGAGCTTGAAAAGCTTGGCGTCACCCC
TTCGGAACTGCTGCGCCAAACCCTGCAGTACGTGGCAGAGCGCGGCCAGTTGCCGTTCAAGACCGTACTGATGACCGAGG
AAGACGAAGCCTTGCTTGCAACAGTGCGCGAGCGCCTTGCGGCTCCGCAACGGGTCAAGGTTTCACTGGATGACTTATAG
Similar Proteins
Only experimentally validated proteins are listed.
Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
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Protein | Organism | Identities (%) | Coverage (%) | Ha-value |
---|
Structures
Toxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0K8M1I3 |
Antitoxin
Source | ID | Structure |
---|---|---|
AlphaFold DB | A0A0K8M1G9 |