Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/ParE-RelB
Location 271738..272257 Replicon chromosome
Accession NZ_CP024712
Organism Pseudomonas syringae pv. actinidiae strain MAFF212063

Toxin (Protein)


Gene name relE Uniprot ID S6W9N2
Locus tag CT122_RS01185 Protein ID WP_017684310.1
Coordinates 271967..272257 (+) Length 97 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID S6UWW5
Locus tag CT122_RS01180 Protein ID WP_002551444.1
Coordinates 271738..271977 (+) Length 80 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CT122_RS01150 266919..267266 - 348 WP_017684314.1 helix-turn-helix domain-containing protein -
CT122_RS01155 267539..268033 - 495 WP_005621707.1 hypothetical protein -
CT122_RS01160 268193..268732 + 540 WP_099978976.1 GNAT family N-acetyltransferase -
CT122_RS01165 268920..269552 + 633 WP_057436493.1 DUF4062 domain-containing protein -
CT122_RS01170 269545..270984 + 1440 WP_017710283.1 putative DNA binding domain-containing protein -
CT122_RS01175 271104..271562 + 459 WP_099978975.1 GNAT family N-acetyltransferase -
CT122_RS01180 271738..271977 + 240 WP_002551444.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CT122_RS01185 271967..272257 + 291 WP_017684310.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CT122_RS01195 272483..273220 - 738 WP_099978974.1 hypothetical protein -
CT122_RS01200 273577..273918 + 342 WP_003380754.1 hypothetical protein -
CT122_RS01205 273995..274607 + 613 Protein_225 histidine phosphatase family protein -
CT122_RS01210 274788..275030 + 243 WP_003380750.1 hypothetical protein -
CT122_RS01215 275020..275303 + 284 Protein_227 type II toxin-antitoxin system RelE/ParE family toxin -
CT122_RS01220 275367..275909 - 543 WP_020312301.1 hypothetical protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-81)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-64)


Sequences

Toxin        


Download         Length: 97 a.a.        Molecular weight: 11145.98 Da        Isoelectric Point: 10.0984

>T88422 WP_017684310.1 NZ_CP024712:271967-272257 [Pseudomonas syringae pv. actinidiae]
MTYSLEFDARALKEWHKLGDTVRQQLKKKLATILVAPRVEANRLHALPDCYKIKLRSSGYRLVYQVIDQEVVVFVVAVDK
RERDEVYRKAADRLGG

Download         Length: 291 bp

>T88422 NZ_CP024712:271967-272257 [Pseudomonas syringae pv. actinidiae]
ATGACTTATAGCCTCGAATTTGATGCGCGAGCTCTGAAGGAATGGCACAAATTAGGCGATACCGTGCGTCAGCAGCTCAA
GAAAAAGCTGGCTACGATTCTGGTTGCTCCGCGTGTTGAAGCAAATCGCCTGCATGCGTTGCCCGACTGCTACAAAATCA
AGCTGCGCAGCAGCGGCTATCGGCTGGTTTATCAGGTTATTGACCAAGAGGTTGTGGTCTTCGTGGTTGCTGTGGACAAG
CGTGAGCGAGATGAGGTTTACCGTAAGGCGGCTGATCGGTTGGGTGGGTAA

Antitoxin


Download         Length: 80 a.a.        Molecular weight: 8955.34 Da        Isoelectric Point: 4.6017

>AT88422 WP_002551444.1 NZ_CP024712:271738-271977 [Pseudomonas syringae pv. actinidiae]
MASINVRIDDDLKARAYLELEKLGVTPSELLRQTLQYVAERGQLPFKTVLMTEEDEALLATVRERLAAPQRVKVSLDDL

Download         Length: 240 bp

>AT88422 NZ_CP024712:271738-271977 [Pseudomonas syringae pv. actinidiae]
ATGGCGTCTATTAATGTTCGTATCGACGACGATCTCAAGGCTCGTGCTTATCTCGAGCTTGAAAAGCTTGGCGTCACCCC
TTCGGAACTGCTGCGCCAAACCCTGCAGTACGTGGCAGAGCGCGGCCAGTTGCCGTTCAAGACCGTACTGATGACCGAGG
AAGACGAAGCCTTGCTTGCAACAGTGCGCGAGCGCCTTGCGGCTCCGCAACGGGTCAAGGTTTCACTGGATGACTTATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure
AlphaFold DB A0A0K8M1I3

Antitoxin

Source ID Structure
AlphaFold DB A0A0K8M1G9

References