Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2146329..2146474 Replicon chromosome
Accession NZ_CP024707
Organism Klebsiella pneumoniae strain cr-hvkp3

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2146365..2146467 (+)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2146329..2146474 (-)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CTM43_RS10410 2141459..2143519 + 2061 WP_004151449.1 oligopeptidase B -
CTM43_RS10415 2143523..2144182 - 660 WP_002911407.1 exodeoxyribonuclease X -
CTM43_RS10420 2144261..2144491 - 231 WP_002911406.1 DNA polymerase III subunit theta -
CTM43_RS10425 2144604..2144978 + 375 WP_004151448.1 CopC domain-containing protein YobA -
CTM43_RS10430 2144982..2145851 + 870 WP_004175431.1 copper homeostasis membrane protein CopD -
CTM43_RS10435 2145868..2146206 + 339 WP_002911404.1 YebY family protein -
- 2146329..2146474 - 146 - - Antitoxin
- 2146365..2146467 + 103 - - Toxin
CTM43_RS28320 2146842..2146985 - 144 WP_002911398.1 Ecr family regulatory small membrane protein -
CTM43_RS10445 2147090..2148058 - 969 WP_004151446.1 VirK/YbjX family protein -
CTM43_RS10450 2148215..2148868 + 654 WP_004891053.1 protein-serine/threonine phosphatase -
CTM43_RS10455 2148865..2149056 - 192 WP_002911395.1 YebW family protein -
CTM43_RS10460 2149154..2149393 - 240 WP_002911393.1 YebV family protein -
CTM43_RS10465 2149509..2150942 - 1434 WP_004148845.1 16S rRNA (cytosine(1407)-C(5))-methyltransferase RsmF -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 103 bp

>T88368 NZ_CP024707:2146365-2146467 [Klebsiella pneumoniae]
GCAAGGCGACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATACA
GGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 146 bp

>AT88368 NZ_CP024707:c2146474-2146329 [Klebsiella pneumoniae]
TAAAGATAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAG
TTGGCATTAATGCAGGCTAAGTCGCCTTGCACTATAAGAATAGTTTAACGCGTCAGCTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References