Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-Axe/YoeB-RelB
Location 1482272..1482779 Replicon chromosome
Accession NZ_CP024705
Organism Fusobacterium pseudoperiodonticum strain KCOM 2653

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag CTN00_RS07455 Protein ID WP_099002724.1
Coordinates 1482519..1482779 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag CTN00_RS07450 Protein ID WP_099991173.1
Coordinates 1482272..1482526 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CTN00_RS07415 1477798..1478007 + 210 Protein_1419 hypothetical protein -
CTN00_RS07420 1478229..1478771 + 543 WP_099985464.1 hypothetical protein -
CTN00_RS07425 1479060..1479866 + 807 WP_099997300.1 hypothetical protein -
CTN00_RS07430 1479892..1480326 + 435 WP_099985463.1 hypothetical protein -
CTN00_RS07435 1480349..1481005 + 657 WP_099991172.1 hypothetical protein -
CTN00_RS07440 1481012..1481392 + 381 WP_099985461.1 hypothetical protein -
CTN00_RS07445 1481409..1481840 + 432 WP_099985460.1 hypothetical protein -
CTN00_RS07450 1482272..1482526 + 255 WP_099991173.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CTN00_RS07455 1482519..1482779 + 261 WP_099002724.1 Txe/YoeB family addiction module toxin Toxin
CTN00_RS07460 1482789..1483292 + 504 WP_099996930.1 GNAT family N-acetyltransferase -
CTN00_RS07465 1483321..1483806 + 486 WP_099996931.1 GNAT family N-acetyltransferase -
CTN00_RS07470 1484047..1484697 + 651 WP_005966059.1 endonuclease III -
CTN00_RS07475 1484777..1485970 + 1194 WP_099996932.1 cysteine desulfurase NifS -
CTN00_RS07480 1486044..1486430 + 387 WP_005973708.1 Fe-S cluster assembly scaffold protein NifU -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10338.93 Da        Isoelectric Point: 9.6577

>T88363 WP_099002724.1 NZ_CP024705:1482519-1482779 [Fusobacterium pseudoperiodonticum]
MNNLVWTHKAWQDYLYWQTQDKKTLKKINELVKDIERNGVLKGIGKPEVLKNESAYSRRIDEKNRLVYRIVDGFIWIIAC
KGHYEE

Download         Length: 261 bp

>T88363 NZ_CP024705:1482519-1482779 [Fusobacterium pseudoperiodonticum]
ATGAATAATTTGGTATGGACGCATAAGGCTTGGCAAGATTACTTATATTGGCAAACTCAGGATAAAAAAACTTTGAAAAA
GATAAATGAATTAGTCAAAGATATTGAAAGAAATGGAGTTTTAAAAGGAATAGGCAAGCCAGAAGTATTAAAAAATGAAA
GTGCATACAGTAGAAGAATTGATGAAAAAAATAGACTGGTTTATAGAATTGTAGATGGTTTTATATGGATAATTGCTTGT
AAAGGTCATTATGAGGAATAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9794.19 Da        Isoelectric Point: 4.5370

>AT88363 WP_099991173.1 NZ_CP024705:1482272-1482526 [Fusobacterium pseudoperiodonticum]
MLAINYTTLRTNLKSYFDKAVDNDEDIIITRKNERNVVLLSLDKYNEFLKAMRNLEYMTKIREGIAELEAGKGVIHDLIE
VDDE

Download         Length: 255 bp

>AT88363 NZ_CP024705:1482272-1482526 [Fusobacterium pseudoperiodonticum]
ATGTTAGCAATTAATTATACAACTTTGAGAACCAATTTAAAAAGTTATTTTGATAAAGCAGTTGATAACGATGAAGATAT
TATTATAACAAGAAAAAATGAGAGAAATGTTGTTCTATTAAGTCTTGATAAATATAATGAGTTTTTAAAAGCTATGAGGA
ATCTTGAATATATGACAAAAATAAGAGAAGGAATAGCTGAATTAGAAGCAGGAAAAGGAGTAATTCATGATTTAATAGAG
GTTGATGATGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References