Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-Axe/YoeB-RelB
Location 2116606..2117113 Replicon chromosome
Accession NZ_CP024702
Organism Fusobacterium pseudoperiodonticum strain KCOM 1282

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag CTM86_RS10430 Protein ID WP_099002724.1
Coordinates 2116853..2117113 (+) Length 87 a.a.

Antitoxin (Protein)


Gene name Axe Uniprot ID -
Locus tag CTM86_RS10425 Protein ID WP_099991173.1
Coordinates 2116606..2116860 (+) Length 85 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CTM86_RS10390 2112039..2112341 + 303 WP_099991171.1 hypothetical protein -
CTM86_RS10395 2112563..2113105 + 543 WP_099985464.1 hypothetical protein -
CTM86_RS10400 2113394..2114200 + 807 WP_099991298.1 hypothetical protein -
CTM86_RS10405 2114226..2114660 + 435 WP_099985463.1 hypothetical protein -
CTM86_RS10410 2114683..2115339 + 657 WP_099991172.1 hypothetical protein -
CTM86_RS10415 2115346..2115726 + 381 WP_099985461.1 hypothetical protein -
CTM86_RS10420 2115743..2116174 + 432 WP_099985460.1 hypothetical protein -
CTM86_RS10425 2116606..2116860 + 255 WP_099991173.1 type II toxin-antitoxin system Phd/YefM family antitoxin Antitoxin
CTM86_RS10430 2116853..2117113 + 261 WP_099002724.1 Txe/YoeB family addiction module toxin Toxin
CTM86_RS10435 2117123..2117626 + 504 WP_099991174.1 GNAT family N-acetyltransferase -
CTM86_RS10440 2117655..2118140 + 486 WP_099991175.1 GNAT family N-acetyltransferase -
CTM86_RS10445 2118137..2118787 + 651 WP_005966059.1 endonuclease III -
CTM86_RS10450 2118867..2120060 + 1194 WP_099991176.1 cysteine desulfurase NifS -
CTM86_RS10455 2120134..2120520 + 387 WP_005973708.1 Fe-S cluster assembly scaffold protein NifU -
CTM86_RS10460 2120716..2122029 + 1314 WP_099989644.1 D-alanyl-D-alanine carboxypeptidase -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(4-84)

Antitoxin

Type II toxin-antitoxin system, antitoxin Phd/YefM

(1-67)


Sequences

Toxin        


Download         Length: 87 a.a.        Molecular weight: 10338.93 Da        Isoelectric Point: 9.6577

>T88358 WP_099002724.1 NZ_CP024702:2116853-2117113 [Fusobacterium pseudoperiodonticum]
MNNLVWTHKAWQDYLYWQTQDKKTLKKINELVKDIERNGVLKGIGKPEVLKNESAYSRRIDEKNRLVYRIVDGFIWIIAC
KGHYEE

Download         Length: 261 bp

>T88358 NZ_CP024702:2116853-2117113 [Fusobacterium pseudoperiodonticum]
ATGAATAATTTGGTATGGACGCATAAGGCTTGGCAAGATTACTTATATTGGCAAACTCAGGATAAAAAAACTTTGAAAAA
GATAAATGAATTAGTCAAAGATATTGAAAGAAATGGAGTTTTAAAAGGAATAGGCAAGCCAGAAGTATTAAAAAATGAAA
GTGCATACAGTAGAAGAATTGATGAAAAAAATAGACTGGTTTATAGAATTGTAGATGGTTTTATATGGATAATTGCTTGT
AAAGGTCATTATGAGGAATAG

Antitoxin


Download         Length: 85 a.a.        Molecular weight: 9794.19 Da        Isoelectric Point: 4.5370

>AT88358 WP_099991173.1 NZ_CP024702:2116606-2116860 [Fusobacterium pseudoperiodonticum]
MLAINYTTLRTNLKSYFDKAVDNDEDIIITRKNERNVVLLSLDKYNEFLKAMRNLEYMTKIREGIAELEAGKGVIHDLIE
VDDE

Download         Length: 255 bp

>AT88358 NZ_CP024702:2116606-2116860 [Fusobacterium pseudoperiodonticum]
ATGTTAGCAATTAATTATACAACTTTGAGAACCAATTTAAAAAGTTATTTTGATAAAGCAGTTGATAACGATGAAGATAT
TATTATAACAAGAAAAAATGAGAGAAATGTTGTTCTATTAAGTCTTGATAAATATAATGAGTTTTTAAAAGCTATGAGGA
ATCTTGAATATATGACAAAAATAAGAGAAGGAATAGCTGAATTAGAAGCAGGAAAAGGAGTAATTCATGATTTAATAGAG
GTTGATGATGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References