Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) yoeB-relB/Txe-DinJ
Location 764649..765181 Replicon chromosome
Accession NZ_CP024701
Organism Fusobacterium pseudoperiodonticum strain KCOM 1277

Toxin (Protein)


Gene name yoeB Uniprot ID -
Locus tag CTM78_RS03970 Protein ID WP_099989059.1
Coordinates 764915..765181 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CTM78_RS03965 Protein ID WP_099989058.1
Coordinates 764649..764915 (+) Length 89 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CTM78_RS03940 760284..760838 + 555 WP_099989054.1 DUF1007 family protein -
CTM78_RS03945 761082..761873 + 792 WP_147384119.1 nickel/cobalt transporter -
CTM78_RS03950 761875..762246 + 372 WP_099989055.1 hypothetical protein -
CTM78_RS03955 762259..762870 + 612 WP_099989056.1 Type 1 glutamine amidotransferase-like domain-containing protein -
CTM78_RS03960 762990..764204 + 1215 WP_099989057.1 MFS transporter -
CTM78_RS03965 764649..764915 + 267 WP_099989058.1 type II toxin-antitoxin system RelB/DinJ family antitoxin Antitoxin
CTM78_RS03970 764915..765181 + 267 WP_099989059.1 Txe/YoeB family addiction module toxin Toxin
CTM78_RS03975 765554..765778 - 225 WP_099971989.1 hypothetical protein -
CTM78_RS03980 766006..767220 + 1215 WP_099989060.1 exodeoxyribonuclease VII large subunit -
CTM78_RS03985 767201..768001 + 801 WP_099989061.1 tetratricopeptide repeat protein -
CTM78_RS03990 768026..768877 + 852 WP_099971992.1 DNA-processing protein DprA -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin YoeB

(5-85)

Antitoxin

RelB antitoxin/Antitoxin DinJ

(1-73)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10383.91 Da        Isoelectric Point: 9.3517

>T88355 WP_099989059.1 NZ_CP024701:764915-765181 [Fusobacterium pseudoperiodonticum]
MKISFSIQAWEEYLYFQTQDKKTLKKINELIKDIERNGALNGIGKPEKLTNNLTGLYSRRINDKDRLVYKLENDFIVILQ
CKGHYSDN

Download         Length: 267 bp

>T88355 NZ_CP024701:764915-765181 [Fusobacterium pseudoperiodonticum]
ATGAAAATTAGTTTTTCTATTCAAGCCTGGGAAGAATATTTATATTTTCAAACTCAAGATAAGAAAACATTGAAGAAAAT
AAATGAACTTATAAAAGATATTGAAAGAAATGGAGCATTGAATGGAATAGGTAAACCTGAAAAACTAACCAATAATTTAA
CAGGATTGTATAGTAGGAGAATCAATGACAAAGATAGATTAGTCTATAAATTAGAAAATGATTTTATAGTTATATTACAG
TGTAAAGGACATTATAGTGATAATTAG

Antitoxin


Download         Length: 89 a.a.        Molecular weight: 10158.86 Da        Isoelectric Point: 4.5609

>AT88355 WP_099989058.1 NZ_CP024701:764649-764915 [Fusobacterium pseudoperiodonticum]
MSMKLVNIRMDEDLKKEMEIVCNDLGINITTAFTIFAKKLTREKRIPFSVSIDPFYSDENIKALENSINEVKDGKVIMKT
IEELEAME

Download         Length: 267 bp

>AT88355 NZ_CP024701:764649-764915 [Fusobacterium pseudoperiodonticum]
ATGTCAATGAAATTAGTAAATATAAGAATGGATGAAGATTTGAAAAAAGAGATGGAAATTGTTTGTAATGATTTAGGTAT
TAATATAACAACTGCATTTACTATATTTGCAAAAAAATTAACAAGAGAAAAAAGAATTCCTTTTAGTGTTTCAATAGATC
CATTTTATTCAGATGAAAATATAAAAGCTTTAGAAAATTCAATTAATGAAGTAAAAGATGGTAAAGTTATTATGAAAACT
ATTGAAGAATTGGAGGCTATGGAATAA

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References