Detailed information of TA system    

insolicoBioinformatically predicted

Overview

TA module


Type II Classification (family/domain) relBE/RelE(toxin)
Location 1618409..1618901 Replicon chromosome
Accession NZ_CP024700
Organism Fusobacterium pseudoperiodonticum strain KCOM 1263

Toxin (Protein)


Gene name relE Uniprot ID -
Locus tag CTM74_RS08540 Protein ID WP_099987789.1
Coordinates 1618635..1618901 (+) Length 89 a.a.

Antitoxin (Protein)


Gene name relB Uniprot ID -
Locus tag CTM74_RS08535 Protein ID WP_099987788.1
Coordinates 1618409..1618627 (+) Length 73 a.a.

Genomic Context

Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CTM74_RS08510 1614030..1614506 + 477 WP_099987783.1 TRAP transporter small permease -
CTM74_RS08515 1614518..1615789 + 1272 WP_099987784.1 TRAP transporter large permease -
CTM74_RS08520 1615804..1616769 + 966 WP_099987785.1 phosphoglycerate dehydrogenase family protein -
CTM74_RS08525 1616865..1617533 + 669 WP_161940324.1 GntR family transcriptional regulator -
CTM74_RS08530 1617635..1618249 - 615 WP_099987787.1 DUF479 domain-containing protein -
CTM74_RS08535 1618409..1618627 + 219 WP_099987788.1 CopG family transcriptional regulator Antitoxin
CTM74_RS08540 1618635..1618901 + 267 WP_099987789.1 type II toxin-antitoxin system RelE/ParE family toxin Toxin
CTM74_RS08545 1619023..1620513 + 1491 WP_099987790.1 cobyric acid synthase -
CTM74_RS08550 1620533..1621459 + 927 WP_099987791.1 DUF4299 family protein -
CTM74_RS08555 1621462..1622460 + 999 WP_099987792.1 cobalamin biosynthesis protein CobD -
CTM74_RS08560 1622547..1622825 - 279 WP_005966535.1 HU family DNA-binding protein -

Associated MGEs

MGE
detail		 Similar
MGEs		 Relative
position		 MGE Type Cargo ARG Virulence gene Coordinates Length (bp)


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Domains

Predicted by InterproScan

Toxin

Toxin-antitoxin system, RelE/ParE toxin family

(5-87)

Antitoxin

Protein of unknown function DUF6290

(3-72)


Sequences

Toxin        


Download         Length: 89 a.a.        Molecular weight: 10296.11 Da        Isoelectric Point: 10.1967

>T88354 WP_099987789.1 NZ_CP024700:1618635-1618901 [Fusobacterium pseudoperiodonticum]
MKYNVEYSKTAMNTIKKLDSLTSKLIRTWIEKNLIDTENPRIKGKALTGDLKGLWRYRVGDYRILADIQDDKIVILILDI
GHRSKIYL

Download         Length: 267 bp

>T88354 NZ_CP024700:1618635-1618901 [Fusobacterium pseudoperiodonticum]
ATGAAATATAATGTGGAATATTCTAAAACTGCTATGAATACTATAAAGAAATTGGATAGTTTAACTTCAAAGTTAATAAG
AACTTGGATAGAGAAAAATTTAATTGATACAGAAAATCCTAGAATAAAAGGTAAAGCCTTAACAGGTGATTTAAAAGGAT
TGTGGCGTTATAGAGTAGGAGATTATAGGATATTAGCTGATATTCAAGATGATAAAATAGTTATCTTAATTTTGGATATA
GGACATAGAAGCAAAATATATTTATAA

Antitoxin


Download         Length: 73 a.a.        Molecular weight: 8494.66 Da        Isoelectric Point: 4.8356

>AT88354 WP_099987788.1 NZ_CP024700:1618409-1618627 [Fusobacterium pseudoperiodonticum]
MGTTATLRLDETEKAIIQNYASSKGMTMSEFMKKVVLDYIEDEYDLKIYKEYLKEKENSTLKTYSHKEVWGE

Download         Length: 219 bp

>AT88354 NZ_CP024700:1618409-1618627 [Fusobacterium pseudoperiodonticum]
ATGGGAACAACAGCAACATTAAGATTAGATGAAACAGAAAAAGCAATCATACAAAATTATGCAAGTAGTAAAGGAATGAC
TATGTCTGAATTTATGAAAAAAGTAGTTCTTGATTATATTGAAGATGAATATGATTTAAAAATTTATAAAGAATATTTAA
AAGAAAAAGAAAATAGTACTTTAAAGACTTATTCACATAAAGAAGTTTGGGGAGAATAG

Similar Proteins

Only experimentally validated proteins are listed.

Protein Organism Identities (%) Coverage (%) Ha-value
Protein Organism Identities (%) Coverage (%) Ha-value

Structures

Toxin

Source ID Structure

Antitoxin

Source ID Structure

References