Detailed information of TA system TA088351

Bioinformatically predicted

Overview

TA module

• Type: IV
• Classification (family/domain): abiEi-abiEii/AbiEii(toxin)
• Location: 611549..612999
• Replicon: chromosome
• Accession: NZ_CP024699
• Organism: Fusobacterium pseudoperiodonticum strain KCOM 1261

Toxin (Protein)

• Gene name: abiEi
• Uniprot ID: -
• Locus tag: CTM72_RS02945
• Protein ID: WP_100024428.1
• Coordinates: 612145..612999 (+)
• Length: 285 a.a.

Antitoxin (Protein)

• Gene name: abiEii
• Uniprot ID: -
• Locus tag: CTM72_RS02940
• Protein ID: WP_100024427.1
• Coordinates: 611549..612148 (+)
• Length: 200 a.a.

Genomic Context

Locus tag	Coordinates	Strand	Size (bp)	Protein ID	Product	Description
CTM72_RS02930	609554..610366	+	813	WP_035939111.1	transketolase	-
CTM72_RS02935	610389..611318	+	930	WP_008820715.1	transketolase family protein	-
CTM72_RS02940	611549..612148	+	600	WP_100024427.1	abortive infection protein	Antitoxin
CTM72_RS02945	612145..612999	+	855	WP_100024428.1	nucleotidyl transferase AbiEii/AbiGii toxin family protein	Toxin
CTM72_RS02950	613195..613962	-	768	WP_100024429.1	DUF695 domain-containing protein	-
CTM72_RS02955	613994..614866	-	873	WP_100024430.1	DUF2262 domain-containing protein	-
CTM72_RS02960	614884..615489	-	606	WP_194250669.1	hypothetical protein	-
CTM72_RS02965	615622..616845	+	1224	WP_100024432.1	replication-associated recombination protein A	-

Associated MGEs

MGE detail	Similar MGEs	Relative position	MGE Type	Cargo ARG	Virulence gene	Coordinates	Length (bp)

Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.

Domains

Predicted by InterproScan

Toxin

• Nucleotidyl transferase AbiEii toxin, Type IV TA system (34-253)

Antitoxin

No domain identified.

Sequences

Toxin

Protein

• Length: 285 a.a.
• Molecular weight: 32672.75 Da
• Isoelectric Point: 5.3319

>T88351 WP_100024428.1 NZ_CP024699:612145-612999 [Fusobacterium pseudoperiodonticum]
MKTSEQIKGAIRNISKKTGVNPNSLLQMCLFEGILEKLSKSKYSENFILKGGLLISSLIGVDMRSTMDMDITLRGIPLNE
ISIRKILNEILAIEIDADIEYKLIKLSPIRQEDMYEDFCASISCIFGKINASLNIDITTGDVITPREINYSYSKILEEGR
IPIMTYTIETILAEKFETISSRNISTTRARDFYDLYMIYSIFKDKINKDVLKKAIERTSKYRGSFETALQYKEIVELFRE
SETSKELWKKYTQNNPYAKNVDFLDTISVYEEIGTVLNIKDDTK

Nucleotide

• Length: 855 bp

>T88351 NZ_CP024699:612145-612999 [Fusobacterium pseudoperiodonticum]
ATGAAAACATCAGAACAGATAAAAGGAGCAATTAGGAATATATCTAAGAAAACAGGAGTTAATCCGAACTCTCTCCTTCA
GATGTGCTTATTTGAAGGAATACTTGAAAAACTCTCCAAATCAAAATATAGTGAAAATTTTATATTAAAAGGTGGACTTC
TTATATCCTCACTTATCGGTGTTGATATGCGTAGTACGATGGATATGGATATCACGCTTAGAGGCATTCCGCTAAATGAA
ATTTCTATAAGAAAAATCTTAAATGAAATATTAGCGATTGAAATTGACGCAGATATCGAATATAAGTTGATTAAACTATC
ACCAATAAGACAAGAAGATATGTATGAAGATTTTTGTGCAAGCATATCCTGTATTTTTGGTAAAATAAATGCAAGCTTAA
ATATAGATATAACGACAGGAGATGTTATTACTCCAAGAGAAATAAATTATTCCTATTCAAAAATCTTAGAAGAAGGTAGA
ATACCAATTATGACCTATACTATAGAAACTATACTTGCTGAAAAATTTGAAACCATTTCAAGCAGAAATATTAGTACAAC
AAGAGCAAGAGATTTCTATGATTTATATATGATATATAGCATTTTTAAAGATAAAATTAATAAAGATGTATTAAAAAAAG
CAATAGAAAGAACGAGTAAATACAGAGGTTCTTTTGAAACAGCTTTACAATATAAGGAAATAGTGGAGTTGTTCCGAGAA
AGCGAAACATCAAAAGAATTATGGAAAAAATATACACAGAATAACCCATATGCTAAAAATGTTGATTTTTTAGATACTAT
ATCAGTCTATGAAGAAATAGGTACTGTATTAAATATAAAAGATGATACTAAATAG

Antitoxin

Protein

• Length: 200 a.a.
• Molecular weight: 23003.92 Da
• Isoelectric Point: 9.8241

>AT88351 WP_100024427.1 NZ_CP024699:611549-612148 [Fusobacterium pseudoperiodonticum]
MSKRELLLKKIKENNGIITTKEALNLGIHKDILKELTVKEEIEKIANGLYALSNENIDEYLYFSYRIPKGIFSHETAAYL
QGLSTRMPLVYVMTVKVGDNVSRVKSARDNIIFKYVKKDYYDIGKITITSPFGREISVYDKERTILDIIKDKGRIDTQVF
SEAIKSYFAGKEKNLLKLLKYAIKMNMEQALKQYTEVLL

Nucleotide

• Length: 600 bp

>AT88351 NZ_CP024699:611549-612148 [Fusobacterium pseudoperiodonticum]
ATGAGTAAACGAGAACTTCTGCTGAAGAAAATAAAAGAAAATAATGGAATTATAACTACAAAAGAGGCTTTAAATCTTGG
TATTCATAAGGATATCCTAAAAGAATTAACCGTAAAAGAAGAAATTGAAAAAATAGCCAATGGACTCTATGCACTTTCAA
ATGAGAACATTGATGAGTATCTTTATTTCTCATATAGAATACCTAAAGGTATTTTTTCTCATGAAACAGCAGCATATTTA
CAAGGATTATCAACACGAATGCCACTTGTTTATGTGATGACTGTAAAGGTAGGGGATAATGTCAGCAGAGTTAAATCTGC
AAGAGATAATATTATTTTTAAGTATGTAAAAAAAGATTATTACGATATTGGGAAAATAACTATAACCAGTCCTTTTGGCA
GAGAAATATCAGTGTATGACAAAGAAAGAACCATACTTGATATTATCAAAGATAAGGGCAGAATAGATACACAAGTATTT
AGTGAAGCAATAAAATCTTACTTTGCAGGTAAGGAGAAAAATTTATTAAAACTCTTGAAATATGCTATTAAGATGAATAT
GGAGCAAGCTTTAAAACAATATACAGAGGTGCTATTATGA