Detailed information of TA system    

insolicoBioinformatically predicted

Overview


TA module


Type VIII Classification (family/domain) SdsR-RyeA/-
Location 2240260..2240401 Replicon chromosome
Accession NZ_CP024677
Organism Citrobacter freundii strain UMH16

Toxin (RNA)


Gene name SdsR
Locus tag -
Coordinates 2240263..2240366 (-)

Antitoxin (RNA)


Gene name RyeA
Locus tag -
Coordinates 2240260..2240401 (+)

Genomic Context


Locus tag Coordinates Strand Size (bp) Protein ID Product Description
CUC48_RS26295 2235537..2235752 + 216 WP_057064237.1 hypothetical protein -
CUC48_RS11220 2235810..2236136 + 327 WP_032944383.1 Rrf2 family transcriptional regulator -
CUC48_RS11225 2236278..2238749 + 2472 WP_121581679.1 exonuclease -
CUC48_RS11230 2238813..2239073 + 261 WP_072211989.1 hypothetical protein -
CUC48_RS11235 2239051..2240130 + 1080 WP_121581681.1 phage integrase Arm DNA-binding domain-containing protein -
- 2240260..2240401 + 142 - - Antitoxin
- 2240263..2240366 - 104 - - Toxin
CUC48_RS11240 2240522..2240860 - 339 WP_003034934.1 YebY family protein -
CUC48_RS11245 2240881..2241753 - 873 WP_032935389.1 copper homeostasis membrane protein CopD -
CUC48_RS11250 2241757..2242131 - 375 WP_003034928.1 CopC domain-containing protein YobA -
CUC48_RS11255 2242275..2242505 + 231 WP_003034925.1 DNA polymerase III subunit theta -
CUC48_RS11260 2242612..2243268 + 657 WP_003841657.1 carbon-nitrogen hydrolase family protein -
CUC48_RS11265 2243292..2243954 + 663 WP_003833802.1 exodeoxyribonuclease X -

Associated MGEs


MGE
detail
Similar
MGEs
Relative
position
MGE Type Cargo ARG Virulence gene Coordinates Length (bp)
- inside Prophage - - 2190270..2246023 55753


Relative position:
(1) inside: TA loci is completely located inside the MGE;
(2) overlap: TA loci is partially overlapped with the MGE;
(3) flank: The TA loci is located in the 5 kb flanking regions of MGE.


Sequences


Toxin        


Download         Length: 104 bp

>T88283 NZ_CP024677:c2240366-2240263 [Citrobacter freundii]
GGCAGGGTAACTTAGCCTGCATTAATGCCAACTTTTAGCGCACGGCTCTCTCCCAAGAGCCATTTCCCTGGACCGAATAC
AGGAATCGTATTCGGTCTCTTTTT

Antitoxin


Download         Length: 142 bp

>AT88283 NZ_CP024677:2240260-2240401 [Citrobacter freundii]
GAGAAAAAGAGACCGAATACGATTCCTGTATTCGGTCCAGGGAAATGGCTCTTGGGAGAGAGCCGTGCGCTAAAAGTTGG
CATTAATGCAGGCTAAGTTACCCTGCCATTTAAGAATAGATGACAGCGCCAGGTTTTCCAGT

Structures


Antitoxin

Download structure file

Antitoxin

Download structure file

References